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미세침흡인으로 얻은 갑상선 유두암 세포에서 p27 발현과 경부림프절 전이의 연관성
이관주,이정의<SUP>1<,SUP>,김정수,김태규<SUP>2<,SUP>,이상철,김정구,안창준,김세준,이동호,Kwan Ju Lee,M,D,Jung Hea Lee,M,D,<SUP>1<,SUP>,Jeong Soo Kim,M,D,Tai Gyu Kim,M,D,<SUP>2<,SUP>,Sang Chul Lee,M,D,Jeong Goo Kim,M,D,Chang-Joon 대한갑상선-내분비외과학회 2009 The Koreran journal of Endocrine Surgery Vol.9 No.3
Purpose: The p27 gene as a tumor suppressor gene is associated with colorectal cancer, gastric cancer and breast cancer. Some studies have shown a relationship between the underexpression of p27 and lymph node metastasis in papillary thyroid carcinoma. The aim of this study is to evaluate the relationship between a p27 expression of the papillary thyroid cancer cells obtained by fine needle aspiration (FNA) and cervical lymph node metastasis. Methods: This study included 60 patients with papillary thyroid cancer and who underwent total thyroidectomy or lobectomy. Central lymph node dissection was routinely done. Out of these patients, 30 patients underwent a FNA procedure during the operation. Immunohistochemical staining for p27 antibody was performed on the papillary thyroid cancer tissues and cells. Results: Cervical lymph node metastasis is correlated with the tumor size and lymphovascular invasion (P<0.001). The underexpression of p27 for the papillary thyroid cancer tissues and cells was associated with lymph node metastasis (P=0.009). Conclusion: An evaluation of the p27 expression for the papillary thyroid cancer cells obtained by FNA may be useful as a predictor for lymph node metastasis before surgery. (Korean J Endocrine Surg 2009;9:155-160)
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이관주,정재희,홍민광,원용성,안창혁,송영택,Lee, Kwan-Ju,Chung, Jae-Hee,Hong, Min-Kwang,Won, Yong-Sung,An, Chang-Hyeok,Song, Young-Tack 대한소아외과학회 2001 소아외과 Vol.7 No.2
Childhood intussusception is usually idiopathic, and pathological lesions as the leading point are found in limited cases. Sixteen operative cases with leadpoints among 2,889 cases of childhood intussusecption treated at the surgical departments of the affiliated hospitals of Catholic University over 19 years are reviewed. The approximate incidence of pathological lesions as the leading point was 0.6%. The male to female ratio was 2:1. The mean age was 3.5 years. There was not an age preponderance. The symptoms were vomiting(63%), abdominal pain(38%), irritability(38%), bloody stools(25%), fever(25%) and abdominal mass(6%). The average duration of the symptoms was 2.4 days(1-10days). The most common lesion was Meckel's diverticulum, followed by malignant lymphomas, polyps, ectopic pancreas, and cecal duplication. An ileocolic type was most frequent, followed by ileoileocolic and ileoileal. Segmental resection or wedge resection of the ileum was done in 10 cases, ileocecectomy in 3, and right hemicolectomy in 3. Surgical reduction was done only in an ectopic pancreas, with no later recurrence. The average hospital stay was 10 days. Postoperative adhesive ileus occurred in two cases, and in one of them adhesiolysis was performed. One case of malignant lymphoma died at 28 days after surgery due to chemotherapy related complication.
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이관주,주영환,Lee, Kwan Ju,Chu, Young Hwan 한국전기화학회 2014 한국전기화학회지 Vol.17 No.2
Cation exchange membrane (Nafion) was modified to reduce the vanadium ion permeation through the membrane and to increase the vanadium redox flow battery (VRB) system performance by coating the graphene oxide (GO) which has nano-plate like morphology. Modified membrane properties were studied by measuring the ion exchange capacity (I.E.C), water uptake and proton conductivity. The thickness of the coated layer on the surface of the Nafion membrane was observed as $0.93{\mu}m$ by SEM. Proton conductivity and vanadium ion permeability of the modified membrane were decreased to 27% and 25% compared to that of the commercial Nafion membrane respectively. VRB single cell performance test was performed to compare the system performance of the VRB applied with commercial Nafion membrane and modified membrane. VRB system applied with modified membrane showed higher coulombic efficiency and energy efficiency than the VRB system applied with the commercial Nafion membrane due to the reduction of the vanadium ion permeation. From these result, we could suggest that the membrane modification by coating the GO on the surface of the Nafion membrane could be one of the promising strategies to reduce the vanadium ion permeation and to increase the VRB system performance effectively.
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