[인터뷰] 서지현: 검사_검찰은 어떻게 정의로워지는가?

서지현,지승호,권영탕(사진) 인물과사상사 2019 인물과 사상 Vol.- No.253

Influencing Factors to Results of the Urease Test: Age, Sampling Site, Histopathologic Findings, and Density of Helicobacter pylori

서지현,윤희상,박정제,염정숙,박지숙,전진수,임재영,박찬후,우향옥,고경혁,백승철,이우곤,조명제,이광호 대한소아소화기영양학회 2013 Pediatric gastroenterology, hepatology & nutrition Vol.16 No.1

Purpose: We investigated the positivity rate and the time period to the positive color change of the urease test in children and adults and assessed the correlation of the urease test to histopathologic findings. Methods: From 1995 to 2000, endoscopic biopsies of the antrum and body were collected from 811 children and 224 adults and subjected to urease tests and histopathology. Results: The positivity rate of the urease test was 49.4% for 0-4 years, 48.4% for 5-9 years, 47.3% for 10-15 years, and 62.5% for 20-29 years in the antrum. The positivity rate was 85.1% in 0-4 years, 82.3% in 5-9 years, 74.7% in 10-15 years, and 74.1% in 20-29 years for the body. In the antrum, the highest positivity rate was <1 hour for the group aged 10-29 years and 6-24 hours in the group <10 years old (p<0.0001). In the body, the highest positivity rate was <1 hour in adults and 6-24 hours in children (p<0.0001). The proportions of the positive reactions within 1 hour were similar for the antrum and the body. In the cases of more severe chronic gastritis, active gastritis, and Helicobacter pylori infiltration, a positive urease test reaction occurred more quickly (p<0.0001). Conclusion: There were significant differences in urease tests according to age and sampling site. The discrepancy between the antrum and the body was greater in younger children. These results might be related to the low density and patchy distribution of bacteria in children and in the body. (Pediatr Gastroenterol Hepatol Nutr 2013; 16: 34∼40)

소아 장중첩증과 혈중 비타민 C의 관계에 관한 연구

서지현,김점수,황지영,전진수,박지회,김은아,임재영,최명범,박찬후,우향옥,윤희상,Seo, Ji-Hyoun,Kim, Jeum-Su,Hwang, Ji-Young,Jun, Jin-Su,Park, Ji-Hoe,Kim, Eun-A,Lim, Jae-Young,Choi, Myoung-Bum,Park, Chan-Hoo,Woo, Hyang-Ok,Youn, Hee-Shang 대한소아소화기영양학회 2001 Pediatric gastroenterology, hepatology & nutrition Vol.4 No.2

Purpose: Adenovirus infection with swollen Peyer patches in the ileum, known as one of the causes of intussusception, may cause vitamin C depletion in human body because vitamin C is a first line antioxidant. Or low vitamin C status in human body makes the man more susceptible to infection of adenovirus in the ileum with a markedly swollen lymph node. In this study, we tried to find out the relationship between pediatric intussusceptions and vitamin C concentrations of whole blood and plasma. Methods: Whole blood and plasma vitamin C concentrations of fifty-seven patients with intussusceptions from May 1995 to December 1998 at the Gyeongsang National University Hospital were compared with those of 256 normal healthy children. Vitamin C was measured by the 2, 4-dinitrophenylhydrazine methods. Results: The average age of patients (male=39, female=18) with intussusceptions was fifteen months of age. Whole blood vitamin C concentrations of patients and healthy children were $1.49{\pm}0.64$ mg/dL, and $2.18{\pm}0.49$ mg/dL, respectively. Plasma vitamin C concentrations of patients and healthy children were $0.59{\pm}0.36$ mg/dL, $1.47{\pm}0.56$ mg/dL, respectively. But no differences in the vitamin C concentrations of whole blood and plasma according to age, degree of leukocytosis, fever, interval from onset, hematochezia, and need for operation were found. Conclusion: Whole blood and plasma vitamin C concentrations of patients with intussusceptions were lower than those of healthy children (P=0.0001). Prospective studies are needed to elucidate whether these results were consequences or causes of intussusceptions.

Association between Gastric pH and Helicobacter pylori Infection in Children

서지현,박형근,박지숙,염정숙,임재영,박찬후,우향옥,윤희상,전진수,고경혁,Seung Chul Baik,이우곤,조명제,이광호,백승철 대한소아소화기영양학회 2015 Pediatric gastroenterology, hepatology & nutrition Vol.18 No.4

Purpose: To assess gastric pH and its relationship with urease-test positivity and histological findings in children with Helicobacter pylori infection.Methods: Fasting gastric juices and endoscopic antral biopsy specimens were collected from 562 children and sub-jected to the urease test and histopathological examination. The subjects were divided into 3 age groups: 0-4, 5-9, and 10-15 years. The histopathological grade was assessed using the Updated Sydney System, while the gastric juice pH was determined using a pH meter.Results: The median gastric juice pH did not differ significantly among the age groups (p=0.655). The proportion of individuals with gastric pH >4.0 was 1.3% in the 0-4 years group, 6.1% in the 5-9 years group, and 8.2% in 10-15 years (p=0.101). The proportions of moderate and severe chronic gastritis, active gastritis, and H. pylori infiltration increased with age (p<0.005). Urease-test positivity was higher in children with hypochlorhydria (77.8%) than in those with normal gastric pH (31.7%) (p<0.001). Chronic and active gastritis were more severe in the former than the latter (p<0.001), but the degree of H. pylori infiltration did not differ (20.9% vs. 38.9%; p=0.186). Conclusion: Gastric pH while fasting is normal in most children regardless of age. Urease-test positivity may be related to hypochlorhydria in children, and hypochlorhydria is in turn related to H. pylori infection.

멕시코 국토 발전과 공간적 조정에 관한 시론적 연구: AMLO 정권하의 트렌 마야 프로젝트를 중심으로

서지현,오인혜 한국세계지역학회 2023 세계지역연구논총 Vol.41 No.4

Mexico has been noted as a somewhat exceptional case in the 2000s, when the Pink Tide wave was exerting a powerful influence in South America. Thus after losing to Mexico’s two conservative parties, PAN and PRI, in 2006 and 2012, expectations for AMLO and his regime, which was elected as the candidate of the MORENA party in 2018, were higher than ever. In particular, it can be said that the regime succeeded in coming to power by emphasising the disconnection from the neoliberal policies implemented by the previous regimes, but in the economic growth policy, it still showed a basis for adjusting and maintaining the existing policy stance rather than an exclusive break with neoliberalism. Against this backdrop, this study aims to examine the reasons why the infrastructure construction project promoted by the AMLO regime has caused social criticism and backlash in the actual process, despite the fact that it specifies the goal of overcoming spatial and social imbalances. This study argues that the emphasis on procedural legitimacy to blunt the backlash against the infrastructure projects actively promoted by the AMLO regime can be understood in the context of the re-establishment or readjustment of the state-market-society relationship, rather than an exclusive break with the previous neoliberal regime. In other words, it is understood as part of a 'spatial fix' to deepen capitalist accumulation as advocated by critical spatial geographers. This study is a preliminary study that aims to overcome the limitations of domestic research on Mexico that has been mainly dealt with in the political, economic, and cultural contexts, and to contribute to the spatial and social discussions. Therefore, it is of academic significance in that it introduces the theoretical discussions of critical geographers who can understand capitalist accumulation and unbalanced land development and applies them to the case of Mexico.

Peperomia 4종의 무늬 발현 양상별 잎의 형태 및 색소 특성 연구

서지현 한국화훼학회 2024 화훼연구 Vol.32 No.2

본 연구는 무늬 식물의 발현 양상을 확인하기 위해 Peperomia 속의 무늬가 없는 P. rotundifolia와 무늬 발생 양상이 서로다른 P. argyreia, P. obtusifolia ‘Variegata’, P. marmorata ‘Pink Lady’4종을 대상으로 잎의 형태적 특성과 색소 구성특성을 비교 분석하였다. 연구 결과, P. argyreia은 배경색과무늬색의 색차(△E)가 크게 나타났지만, 단면 세포에서는 엽록소가 고르게 분포하고, 색소 구성에서 무늬 유무에 따른 차이가 없었다. 반면, c ‘Variegata’는 색소 구성에서 배경색과무늬색 사이에 유의적인 차이를 보였다. 단면 세포에서도 엽록소 분포의 차이가 뚜렷이 관찰되었다. 붉은 색의 무늬를 가진 P. marmorata ‘Pink Lady’는 안토시아닌을 포함하고 있어, 다른 품종들과는 다르게 색소체 생성에 따른 무늬 발현 양상을 보였다. 결론적으로, P. argyreia는 표피의 공기층에 의해 무늬가 발현되는 구조적 패턴을 가지며, P. obtusifolia ‘Variegata’와 P. marmorata ‘Pink Lady’는 엽록소와 카르티노이드, 안토시아닌 등 색소적 특징에 의해 무늬를 발현시키는 것으로 확인되었다. 이처럼 품종 특이적으로 다른 무늬발생 양상을 가진 식물은 관상 가치를 유지하기 위한 광환경이 다르게 요구될 것으로 판단된다. To identify the expression pattern of variegated plants, this study compared the morphological characteristics and pigment composition of leaves of four species of Peperomia with different development patterns: nonpatterned P. rotundifolia, P. argyreia, P. obtusifolia ‘Variegata’, and P. marmorata ‘Pink Lady’. Results showed a large color difference (△E) between the background and pattern colors in P. argyreia; however, chlorophyll was evenly distributed in cross-sectional cells, with no difference in pigment composition observed in the presence or absence of a pattern. Conversely, P. obtusifolia ‘Variegata’ showed significant differences in pigment composition between the background and pattern colors. Differences in chlorophyll distribution were also evident in cross-sectioned cells. P. marmorata ‘Pink Lady’, which has a reddish pattern, contained anthocyanins and had a different expression pattern due to plastid production. In conclusion, P. argyreia has a structural pattern caused by the air layer of the epidermis, while the patterns in P. obtusifolia ‘Variegata’ and P. marmorata ‘Pink Lady’ develop due to the presence of pigments, such as chlorophyll, carotenoids, and anthocyanins. Plants with these cultivar-specific patterns of variegation development may require different light conditions to maintain their ornamental value.

풀뿌리 환경주의의 관점에서 본 라틴아메리카 토지의 의미 변화: 멕시코 EZLN과 브라질 MST 사례를 중심으로

서지현 한국라틴아메리카학회 2024 라틴아메리카연구 Vol.37 No.1

In Latin America, the land has been an important issue in driving political and social change since the end of the 15th century, when European conquistadores began their colonial rule, to the present. The purpose of this study is to examine the changing meaning of land, by looking at cases of the Latin America’s most representative rural social movements, i.e. EZLN in Mexico and MST in Brazil. In particular, this study distinguishes two currents of environmentalism in Latin America: elitist environmentalism and grassroots environmentalism. The former understands nature as a natural resource that can be developed or nature that needs to be preserved from a human-centric point of view, based on the ‘modern Western view of nature.’The latter understands the environment from the perspective of 'socionature', which is not simply a nature that is used and appreciated by human beings, but a morethanhuman ecological space, that is, a space where humans and nature coexist. In this context, the meaning of land demanded by Mexico's EZLN and Brazil's MST can be better understood from the perspective of grassroots environmentalism. Both the EZLN and the MST call for land reform, which is not limited to the sense that land is arable land in the economic and social sense that must be secured for capitalist production in the process of agricultural modernisation or under a globalised system of agricultural production. Rather, their demand for land is closely related to the demand for productive justice that can sustain a human life through alternative modes of production, rather than the current mainstream model of development, and the demand for recognition of the political space(territory) that can determine these alternative modes of production and ways of life. Thus, land in these movements can be understood as territory as a political and ecological space for alternative development, beyond the meaning of economic and social arable land.

Changes in Anti-Group A Rotavirus Antibody Seroprevalence and Levels in the Western Gyeongnam Province of Korea Over 16 Years

서지현,박정제,임재영,전진수,박찬후,우향옥,윤희상,권영철,강형련,백승철,이우곤,조명제,이광호,김원용 대한의학회 2013 Journal of Korean medical science Vol.28 No.1

To observe how anti-group A rotavirus antibody seropositivity rates and levels have changed in the western region of Gyeongnam Province, 2,030 serum samples collected at four collection periods (1989-1990, 1994-1995, 1999-2000, and 2004-2005) were tested by Enzyme-Linked Immunosorbent Assay for IgG, and IgA antibodies reacting to recombinant VP6 protein. The seroprevalences exhibit no regular patterns over a 16-yr period. For all four collection periods, the anti-rVP6 IgG levels rose steadily during the first 5 months of life, after which they remained high. However, the 2-9 yr and 10-39 yr groups had significantly higher IgG levels in 1999-2000 and 2004-2005, respectively, than in the other collection periods. The 1-5 mo, 40- ≥ 60 yr, and 4-29 yr groups had significantly higher IgA levels in 1989-1990, 1999-2000, and 2004-2005, respectively. The 4 yr (25.0%), 5-9 yr (18.8%), 10-14 yr (41.1%), 20-29 yr (35.0%), and 30-39 yr (20.0%)groups in 2004-2005 had significant higher IgA seropositivity rate compared to the other three collection periods. These observations suggest that in the western region of Gyeongnam Province since the late 1990s, rotavirus reinfection has occurred more frequently than previously, with all ages being at risk.

외국대학 의과대학생들의 농어촌 지역 임상실습 경험이 미래 진로에 미치는 영향

서지현 대한의사협회 의료정책연구원 2023 의료정책포럼 Vol.21 No.2

Poor Health-Related Quality of Life and Proactive Primary Control Strategy May Act as Risk Factors for Acute Coronary Syndrome

서지현,이윤표,강석형,전혜진,편욱범,박성훈,정경미,정익모 대한심장학회 2015 Korean Circulation Journal Vol.45 No.2

Background and Objectives: Increasing evidence supports that psychological factors may be related to development of coronary arterydisease (CAD). Although psychological well-being, ill-being, and control strategy factors may play a significant role in CAD, rarely havethese factors been simultaneously examined previously. We assessed comprehensive psychological factors in patients with acute coronarysyndrome (ACS). Subjects and Methods: A total of 85 ACS patients (56 unstable angina, 29 acute myocardial infarction; 52.6±10.2 years; M/F=68/17)and 63 healthy controls (48.7±6.7 years, M/F=43/20) were included. Socio-demographic information, levels of psychological maladjustment,such as anxiety, hostility, and job stress, health-related quality of life (HRQoL), and primary and secondary control strategy use werecollected through self-report questionnaires. Results: There was no significant difference between the ACS group and control group in levels of anxiety, hostility, and job stress. However,ACS patients had significantly lower scores on the general health perception and bodily pain subscales of HRQoL than the control group. The ACS group, as compared with the controls, tended to use primary control strategies more, although not reaching statistical significanceby univariate analysis. Multivariate logistic regression analysis after adjusting age and gender identified the physical domain of HRQoL{odds ratio (OR)=0.40}, primary control strategy (OR=1.92), and secondary control strategy (OR=0.53) as independent predictors of ACS. Conclusion: Poor HRQoL and primary control strategy, proactive behaviors in achieving ones’ goal, may act as risk factors for ACS, whilesecondary control strategy to conform to current situation may act as a protective factor for ACS.