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- 저자 : 박일규 ( Il Goo Park ) (검색결과 2 건)
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유우(乳牛)의 발굽 질환(疾患) 발생조사(發生調査) 및 치료(治療)에 관(關)한 연구(硏究)
신창호 ( Chang Ho Shin ),김성민 ( Sung Moon Kim ),배영재 ( Young Jae Bae ),박일규 ( Il Goo Park ),정태수 ( Tae Soo Jung ) 한국가축위생학회 1990 韓國家畜衛生學會誌 Vol.13 No.2
The present study was carried out to investigate the agent of foot disease of cattles, to develop the therapeutics. The results obtained were as follows; 1. Sixty eight heads of cattle affected foot rot during the observation period and the incidence rate shown 3.25%. 2. The high incidence was observed on September and October. 3. The disease was more frequently seen affecting in hindlimbs than forelimbs. 4. The disease was more frequently seen affecting in older cattles and higher milk production cow. 5. Isolated strains were shown E. coli (20.6%), Staphylococcus SPP (17.6%), stridium SPP (22.1%), Fusobacterium SPP (20.6%), Bacteroid SPP (19.1%).
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칼시토닌 고분자 미립자 투여에 따른 골다공증 유발 쥐의 골밀도 변화
최정원(Jeong won Choi),정제순(Je soon Jung),이상건(Sang Gun Lee),백두진(Doo Jin Paik),박일규(Il Kyu Park),박용구(Yong Goo Park),김미정(Mi Jung Kim) 대한임상노인학회 2003 대한임상노인의학회지 Vol.4 No.4
Objective: To evaluate bone protective effects of salmon calcitonin microspheres against cancellous bone loss in ovariectomized rats. Method: Thirty five osteoporosis-induced Sprague-Dawley rats were randomly divided into five groups (high dose calcitonin group (112 U/kg), low dose calcitonin group (56 U/kg), free calcitonin group, only ovariectomy group, control group). Ovariectomized rats were injected s.c. with salmon calcitonin microspheres(l12 U/kg or 56 U/kg) weekly, and free salmon calcitonin on alternate days. control rats and the remaining ovariectomized rats were injected s.c. on alternate days with saline vehicle. The effects and side effects in each group were assessed by the bone mineral density and bone histomorphomeσy. Results: 1. At four months after the ovariectomy, the bone mineral densities in high dose calcitonin group were 0.1640±0.0156 grn/㎠, the bone mineral densities in low dose calcitonin group were 0.1600±0.0114 gm/㎠, the bone mineral densities in calcitonin group were 0.1531±0.0168 gm/㎠, the bone mineral densities in ovariectomy group were 0.1404±0.0070 gm/㎠, the bone mineral densities in control group were 0.1896±0.0163 gm/㎠. The bone mineral densities of the femur in ovrariectomy groups compared with control group were decreased with time. The difference of the bone mineral densities between high and low dose calcitonin group and ovariectomy groups was significant (p<0.05). 2. We found that the bone trabeculi in bone histomophometry were more maintained in high dose calcitonin group compared with ovariectomy group. Conclusion: 1. Bone mineral densities of salmon calcitonin microsphere injected rats was higher than only ovariectomized rats in femur. 2. Bone mineral densities of salmon calcitonin microsphere injected rats had no significant differences than only ovariectomized rats in L5 vertebra. 3. In histologic examination, salmon calcitonin microsphere and free salmon calcitonin injected rats showed more prominent bony trabeculae than ovariectomized rats.
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