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난소적출 및 수종 Hormone투여가 치아및 치은의 Collagen 생합성에 미치는 영향에 관한 실험적 연구
박우찬,정동균 대한구강생물학회 1980 International Journal of Oral Biology Vol.4 No.1
The effects of ovariectomy, several hormones and fluoride on the collagen turnover in teeth, pulp and gingiva were studied employing the Sprague-Dawley female rats. The rats were divided into non-treated and treated group, and treated group on which had been performed ovariectomy operation, was further subdivided into 5 groups, i.e., control, estrogen, testosterone, prednisolone and fluoride administered group. Then, each group was treated with ^3H-proline and sacrificed according to a predetermined schedule. Pulp, teeth and gingiva were removed immediately and decalcified for 3 days. After digestion of samples, separation and quantitative analysis of proline and hydroxyproline were performed employing thin layer chromatography and radioactivity of seperated amino acid was assayed by liquid scintillation counter. The results were as follows ; 1. In non-treated group, the incorporation rate of ^3H-proline into hydroxy-proline was greater in pulp of teeth than in hard tissue of teeth and gingiva. Collagen turnover of lower root, lower pulp and gingiva was more rapid than any other tissues tested. 2. In all the tissues from ovariectomized rats, the incorporation of ^3H-proline into collagen was markedly decreased. 3. The decreased effect of ^3H-proline incorporation into collagen by ovariectomy was markedly antagonized with estrogen, moderately or slightly with testosterone in all the tissues tested, whereas fluoride had a slightly antagonizing effect only in th lower incisor roots. The effect of ovariectomy on collagen turnover was augmented or not influenced by prednisolone.
유방암 수술 결정을 위한 수술 전 자기공명영상의 임상적 의의
박우찬 한국유방암학회 2006 Journal of breast cancer Vol.9 No.4
Purpose: Currently MRI (Magnetic Resonance Imaging) is widely used for the preoperative staging of breast cancer. In this study, we assessed the impact of preoperative breast MRI on the surgical management of breast cancer in women. Methods: From March 2004 to October 2006, 162 cases were enrolled for preoperative MRI for the staging of breast cancer. The MRI findings and clinicopathological results were investigated and the accuracy of breast MRI was analyzed with respect to the detection of multiplicity, nipple involvement and bilaterality of the breast cancers. Results: For detecting multifocal lesions, the sensitivity and specificity of breast MRI were 100% and 48.5%, respectively, and the results of bresat ultrasound were 100% and 63.4%, respectively. For detecting nipple invasion, the sensitivity and specificity of breast MRI was 80% and 74.6%, and for ultrasound was 33.3% and 86.4%. In 27 cases (16.7%) the type of surgery was changed according to the preoperative MRI findings; however, in only 6 cases were the MRI findings in concordance with the pathological findings of the mastectomy specimen. Conclusion: In clinical application of breast MRI for preoperative staging, the decision to undertake surgery for breast cancer based on a MRI findings should be prudent due to its low specificity.
광선 추적법 텍스쳐 매핑을 위한 MIP-Map 수준 선택 알고리즘 연구
박우찬,김동석 한국게임학회 2010 한국게임학회 논문지 Vol.10 No.4
본 논문은 광선 추적법 텍스쳐 매핑에서 MIP-Map 알고리즘 사용 시 텍스쳐 이미지들의 MIP-Map 수준을 선택하는 효과적인 방식을 제안한다. 이는 렌더링 시 물체와 교차하는 광선의 길이만을 사용하여 해당 물체의 텍스쳐 MIP-Map 수준을 선택하는 방법이다. 본 방식은 MIP-Map을 지원하지 않는 방식에 비하여 텍스쳐 알리아싱 면에서 우수하고 성능 저하는 미비하다. This paper proposes an effective method to select MIP-Map level of texture images for ray-traced texture mapping. This MIP-Map level selection method requires only the total length of intersected ray. By supporting MIP-Map for texture mapping, we can reduce the texture aliasing effects, while our approach decreases rendering performance very slightly.
X-ray Data Analysis to Search for Magnetar Candidates in the Galactic Plane
박우찬,안홍준 한국우주과학회 2018 Journal of Astronomy and Space Sciences Vol.35 No.3
We report on our Galactic plane searches for magnetars in the archival Chandra X-ray Observatory (CXO) data. We summarize the properties of known magnetars and use them to establish a procedure for magnetar searches. The procedure includes four steps: source finding, spectral characterization, optical counterpart checks, and period searches. We searched 1,282 archival CXO observations, found 32,838 X-ray sources, and selected 25 intriguing candidates using the developed procedure. Although we do not firmly identify a magnetar among them, we significantly reduced the number of targets in future magnetar searches to be done with better X-ray telescopes.
동적 장면을 지원하는 효율적인 광선 추적 하드웨어에 대한 FPGA상에서의 구현
박우찬,이진영,김정길 한국반도체디스플레이기술학회 2022 반도체디스플레이기술학회지 Vol.21 No.4
In this paper, our ray tracing hardware is implemented on the latest high-capacity FPGA board. The system included ray tracing hardware for rendering and tree building hardware for handling dynamic scenes. The FPGA board used in the implementation is a Xilinx Alveo U250 accelerator card for data centers. This included 12 ray tracing hardware cores and 1 tree-building hardware core. As a result of testing in various scenes in Full HD resolution, the FPS performance of the proposed ray tracing system was measured from 8 to 28. The overall average is about 17.7 FPS.