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김혁 한국중국언어학회 2018 중국언어연구 Vol.0 No.74
This paper gives a new interpretation of ‘’ And ‘’the two characters. About ‘’, according to the evidence of gramatology and the inscriptions cases, this paper presented the view that ‘’ is the omitted form of ‘’(直). With regard to the problem of ‘’, from the question of the character itself, and according to Oracle Bone Inscription, the author puts forward the view that ‘’ is interpreted as JinDeng(今登). But there is only one example of ‘’ And ‘’the two characters. At the same time, when ‘’ is explained, the author has put forward three evidence, and there are many problems in all aspects. Therefore, the opinion that I put forward can not be completely determined at present. It is hoped that through further research and new unearthed data to supplement the evidence, we can solve the fundamental problems in the ‘’ And ‘’the two characters. 本文對甲骨文‘’、‘’兩個字進行了新的考釋。關於‘’字問題,筆者根據文字學證據和卜辭辭例,提出了將‘’字認為‘’(直)字異體的看法。關於‘’字問題,從字形本身的問題出發,同時根據甲骨文類組學(即歷組卜辭刻手的書寫習慣),提出了將‘’字認為‘’(今)‘’(登)的二字合書的看法。但是‘’、‘’兩個字各有一例,根本不能提出更多的例子。又,對‘’字進行考釋時筆者提出的三個證據,在文字、辭例等方面存在不少問題。因此,筆者提出的意見目前還不能完全確定。希望通過今後的深入研究和新出土資料的補證,能解決在‘’、‘’兩個字上存在的根本問題。
김혁,유정주 대한의사협회 2024 대한의사협회지 Vol.67 No.9
Background: This study aimed to summarize evidence of ursodeoxycholic acid (UDCA) use in the management of hepatobiliary diseases, present indications for UDCA use in Korea, and reimbursement criteria for UDCA use in the country. Current Concepts: UDCA is currently approved for the treatment and prevention of gallstone in obese patients with rapid weight loss after post-bariatric surgery, primary biliary cirrhosis (PBC), chronic liver disease with markedly elevated liver function test values, and chronic hepatitis C. However, the approval and reimbursement criteria for UDCA depend on the dose, specific diseases, and circumstances. UDCA is administered at doses of 100, 200, and 300 mg. The 100 mg dose is available over-the-counter, whereas a prescription is required for the 200 and 300 mg doses. The approval standards differed by dose: UDCA 100 mg for biliary diseases and chronic liver disease; UDCA 200 mg for gallstone, PBC, and chronic hepatitis C; and UDCA 300 mg for PBC, gallstone prevention in obese patients, and patients who had undergone gastrectomy. Co-administration of UDCA with antiviral drugs may require patients to bear some costs. UDCA can be combined with either milk thistle or biphenyl dimethyl dicarboxylate but not both. Discussion and Conclusion: UDCA is a relatively safe medication with many benefits. The current reimbursement standards for hepatobiliary diseases include chronic liver disease with elevated liver enzyme levels, gallstone, PBC, chronic hepatitis B, and chronic hepatitis C. Because UDCA is administered at varied doses, it is important to know the appropriate dose and regimen for each condition.
대계 추출물의 할성산소 소거능 및 Cytochrome P450 효소 저해효과
김혁,이효승,박원환,문진영,Kim, Hyuck,Yi, Hyo-Seung,Park, Won-Hwan,Moon, Jin-Young 대한본초학회 2007 대한본초학회지 Vol.22 No.1
Objectives: Our previous studies have clearly demonstrated that the scavenging activity of reactive oxygen species (ROS), protective effect of lipid peroxidation (LPO), and inhibition of cytochrome P450 isozymes (CYPs) from the Circium japonicum aqua-acupuncture solution (CJAS). But, Circium japonicum water extracted solution (CJWS) was weakly reported in cardiovascular diseases such as oxidative stress-mediated atherosclerosis or its value evaluated. Methods: CJWS was assessed to determine the mechanism of its scavenging activity of ROS and inhibitory effect of CYP 2E1. Results: CJWS exhibited a concentration-dependent scavenger of DPPH and superoxide anions radicals using different assay systems. In addition, CJWS showed dose-dependent free radical scavenging activity, including hydroxyl radicals, peroxynitrite, and nitric oxide. The CJWS was also found to be effective in protecting rat liver homogenate against LPO. Futhermore, the CJWS showed significant inhibition of CYP 2E1 induced by pyrazol in a rat liver microsome. Conclusion : ROS and CYPs may play a role in several diseases, such as cardiovascular disease and heart failure. Our study demonstrated that the CJWS has excellent scavenging activity of ROS. Hence, it is worthwhile to investigate the potential effectiveness of CJWS in preventing oxidative stress-mediated cardiovascular diseases.

우측상대정맥 없이 좌측 상대정맥이 좌심방으로 유입되는 활로씨 사징증의 수술치험 1례
김혁,김병일,김남수,김영학,정원상,강정호,지행옥,이철범,전석철,Kim, Hyuk,Kim, Byoung-Il,Kim, Nam-Su,Kim, Young-Hak,Chung, Won-Sang,Kang, Jung-Ho,Jee, Heng-Ok,Lee, Chul-Bum,Jeon, Seok-Chol 대한흉부심장혈관외과학회 1999 Journal of Chest Surgery Vol.32 No.12
A persistent left superior vena cava draining into the coronary sinus is the most benign and widely encountered abnormality and can easily be explained embryologically as the persistence of the usual pattern of vnous circulation in the embryo,. However a persistent left superior vena cava draining into the left atrium with absent right superior vena cava is an extremely rare anomaly. We report this situation in an infant with tetralogy of Fallot. The most common approach has traditionally been intraatrial baffle repair to create a tunnel to the right atrium or rerouting of the left superior vena cava flow by directly anastomosing the left superior vena cava to the right atrium In the present study the left superior vena cava was transposed to the left pulmonary artery after the correction of tetralogy of Fallot. The most common approach has traditionally been intraatrial baffle repair to create a tunnel to the right atrium or rerouting of the left superior vena cava flow by directly anastomosing the left superior vena cava to the right atrium. In the present study the left superior vena cava was transposed to the left pulmonary artery after the correction of tetralogy of Fallot.

김혁,유재현,서필원,이원용,백완기,박국양,이영탁,박영관,홍승록,이영균,Kim, Hyuk,Yu, Jae-Hyeon,Seo, Pil-Won,Lee, Won-Yong,Baek, Wan-Ki,Park, Kook-Yang,Lee, Young-Tak,Park, Young-Kwan,Hong, Sung-Nok,Lee, Yung-Kyoon 대한흉부심장혈관외과학회 1994 Journal of Chest Surgery Vol.27 No.4
Between 1985 and 1993, 29 children from 1 to 15 years of age have undergone cardiac valve replacements at Buchon Sejong Hospital. The patients were composed of 20 males and 9 females and 17 patient had congenital heart disease and 12 patients had acquired heart disease. Two of these patients have had second valve replacements due to paravalvular leakage and valve thrombosis. Single valve replacements were 29 and double valve replacements were 2. All the patients had received prosthetic valves except one. Among the 25 patients who had definite post-operative records, the overall mortality was 12%[4% was early mortality and 8% was late mortality].25 patients were followed up with coumadin anticoagulation for total 633 patient-months[minimum 2 months to maximum 93 months, mean 25.3 months] and actuarial survival rate was 88.5 $\pm$ 6.3% at 7 years and event free rate was 70.3 $\pm$ 11.7% at 7 years. These results suggest that pediatric valve replacements can now be performed at a low operative risk although various problems are still remained and the choice of valve is prosthetic valve mainly due to its durability at the present time.
자발성 혈흉을 동반한 후종격동 신경섬유초종 -1예 보고-
김혁,양주민,정기천,김영학,강정호,정원상 대한흉부외과학회 2004 Journal of Chest Surgery Vol.37 No.12
Neurogenic tumors are common in posterior mediastinal tumors. In most cases, tumors were accidentally showed on simple chest X-ray. In some cases, they were presented by symptoms which were induced by nerve compression or airway compression. But as in our case, neurogenic tumor with spontaneous hemothorax is very rare. A 45-year-old man admitted to emergency room of other hospital because of acute right chest pain and dyspnea. A chest X-ray showed a right pleural effusion. Hemothorax was diagnosed after closed thoracostomy. Following chest CT showed posterior mediastinal mass. The patient was transferred to our hospital. T spine MRI showed dumbbell shaped mass. Diagostic impression was neurogenic tumor. The pathologic result was neurilemmoma after surgical resection. 신경종은 후종격동 종양의 흔한 형태이며 주로 증상 없이 단순흉부촬영상 우연히 발견되거나 흉통이나 요통 등의 신경압박증상이나 기관지를 압박하여 나타나는 증상 등에 의해 발현되기 쉽다. 하지만 본 증례와 같이 자발성 혈흉을 일으키는 경우는 극히 드물다. 환자는 45세 남자로 갑자기 생긴 흉통 및 호흡곤란을 증상으로 타 병원 응급실 내원하여 시행한 단순흉부촬영상 우측 늑막삼출이 의심되어 폐쇄성 흉관삽입술 후 혈흉으로 진단되었고 흉부 전산화단층촬영상 후종격동 종양 소견 보여 본원으로 전원되었다. 전원 후 시행한 흉추 자기공명영상촬영상 아령모양의 신경종 의심되어 수술적 절제를 시행하였고 병리조직검사상 신경섬유초종으로 판명되었다.