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- 저자 : 김태일 ( Tae Il Kim ) (검색결과 633 건)
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사람 치은 섬유아세포에서의 Tannerella forsythia 전세균, 막단백질, 당지질에 의한 염증성 사이토카인 발현
김정은,이성훈,최봉규,구기태,김태일,이용무,구영,정종평,류인철,Kim, Jung-Eun,Lee, Sung-Hoon,Choi, Bong-Kyu,Koo, Ki-Tae,Kim, Tae-Il,Lee, Yong-Moo,Ku, Young,Chung, Chong-Pyoung,Rhyu, In-Chul 대한치주과학회 2008 Journal of Periodontal & Implant Science Vol.38 No.3
Purpose: The purpose of this study was to investigate induction of cytokine expression in human gingival fibroblasts (HGFs) by whole cell and the components of T. forsythia. Material and Methods: After HGFs were treated with lipopolysaccharide (LPS), membrane protein isolated from T. forsythia or culture media of T. forsythia, the induction of interleukin (IL)-1, IL-6 and IL-8 was examined with real-time PCR and ELISA. Their induction ability of cytokines was compared with whole bacteria. Result: The expression of IL-6 and IL-8 was significantly induced in HGFs by whole bacteria and membrane protein. The expression of IL-$1{\beta}$ was induced by membrane protein of T. forsythia, not by whole bacteria. LPS and condition media of T. forsythia slightly activated HGFs. Conclusion: The membrane protein of T. forsythia could be one of virulence factors.
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김태일(Kim Tae Il) 한국국가법학회 2012 국가법연구 Vol.8 No.2
May 21, 2009. The 'Case of grandma Kim' that was highlighted as an issue in Korea. It led to the result that recognized initially in Korea about death with dignity. Since the initial sentence that recognized the death with dignity by the Supreme Court, It was actively discussed by configure the related social council and activities or Taking the initiative by Shin sang jin. But it couldn't draw a conclusion by religious community, the medical profession and related legal system etc. However, recently, the try are showing again. Nowadays discussions and interests about death with dignity are increasing gradually to government and whole of society. Therefore, examine the each countries opposing discussion. And should be sought reasonable solutions for its admissibility and validity. And to prepare the related legislation, review all the matters to National Bioethics Committee and in charge of the advice and decision about family. And if they can control the process of treatment interruption through the Commission. Then, it will be able to achieve the social consensus about the basis of treatment's discontinuation and will be able to escape from present practice that made by agreement between the family and the individual physician under the unclear standard. The decision of the judgment between 'unrecoverable patients' and 'terminal patients' is the decision of the judgment between 'unrecoverable patients' and 'terminal patients' is including the clear procedures that be the basis of judgment for medical standards of judgment. Also, may be considered the ways that participation of at least two or more doctors. The unrecoverable patients, they do not have the opportunity to express their free opinions. So, substitute for specific others and need to consider the agent's consent. In this case, the legal controversy arises which is the agent's decision about life and the patients' own decision are same. In order to overcome this, the preparation of the legal basis is essential about agree on the consent of agents.
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Probiotics가 대장암 세포주의 IL-8 생성에 미치는 영향
최창환 ( Choe Chang Hwan ),이상길 ( Lee Sang Gil ),양경민 ( Yang Gyeong Min ),채보아 ( Chae Bo A ),김태일 ( Kim Tae Il ),김원호 ( Kim Won Ho ) 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<목적> Probiotics는 살아있는 organism으로서 사람이 복용하였을 때 건강에 이로운 효과를 나타내는 것을 말하며, 최근 염증성장질환의 치료에 있어서 probiotics의 효과에 대해 많은 연구가 이루어지고 있다. 살아있는 비병원성 Salmonella 균주를 이용한 연구 보고에 의하면, 대장암 세포주에 염증성 자극 후 인산화된 I-κBα의 ubiquitination을 이 균주가 억제하여 염증반응을 억제한다고 하였다. 하지만 이러한 항염증 기전
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위장관 ; Lipopolysaccharide로 유도된 HT-29 세포주의 염증에서 Lactobacillus rhamnosus GG의 항염증 작용과 기전
이상길 ( Sang Kil Lee ),양경민 ( Kyung Min Yang ),천재희 ( Jae Hee Cheon ),김태일 ( Tae Il Kim ),김원호 ( Won Ho Kim ) 대한소화기학회 2012 대한소화기학회지 Vol.60 No.2
Background/Aims: Probiotics are live non-pathogenic organisms that belong to the resident microflora, and confer health benefits by multiple mechanisms. Lactobacillus rhamnosus GG (LGG) is one of the probiotic bacteria that ameliorates intestinal injury and inflammation caused by various stimuli. We aimed to evaluate the anti-inflammatory effect and mechanism of LGG in lipopolysaccharide (LPS)-stimulated HT-29 cells. Methods: HT-29 cells were stimulated with interleukin (IL)-1β (2 ng/mL), tumor necrosis factor (TNF)-α (20 ng/mL), and LPS (20 μg/mL) in the presence or absence of LGG (107-109 colony forming units/mL). Production of the pro-inflammatory chemokine IL-8 was measured by ELISA and semi-quantitative PCR. Transcriptional activity of NF-κB-responsive gene was evaluated by luciferase assay with reporter gene. Toll-like receptor 4 (TLR4) mRNA expression was assessed by semi-quantitative PCR. The IκBα degradation was evaluated by western blot and intranuclear translocation of NF-κB was determined by western blot and immunofluorescence. Results: LGG did not affect the viability of HT-29 cells. Pretreatment of HT-29 cells with LGG significantly blocked TNF-α, and LPS induced IL-8 activation at both mRNA and protein level (p<0.05). Pretreatment of HT-29 cells with LGG attenuated LPS-induced NF-κB nuclear translocation and also blocked LPS-induced IκBα degradation. LGG also down-regulated TLR4 mRNA activated by LPS. Conclusions: LGG attenuates LPS induced inflammation, and this may be associated with TLR4/NF-κB down-regulation. (Korean J Gastroenterol 2012;60:86-93)
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혀 세정기가 부착된 수동칫솔이 치아와 혀의 세정도 및 구취 관리도에 미치는 영향
김태일,홍삼표,이신재,강봉선,오영상,김인경,오미현,Kim, Tae-Il,Hong, Sam-Pyo,Lee, Shin-Jae,Kang, Bong-Sun,Oh, Young-Sang,Kim, In-Kyung,Oh, Mi-Hyun 대한치주과학회 2008 Journal of Periodontal & Implant Science Vol.38 No.4
Purpose: The aim of this study was to investigate the effect of tongue cleaner-equipped manual toothbrush on tooth cleanness, tongue cleanness and malodor index. Materials and methods: 504 subjects were included in this study. At 1st visit, basic information such as age, sex, smoking amount and alcohol consumption was recorded. Self assessment by individual subjects was performed regarding satisfaction to old toothbrush and toothbrushing habit. Tooth cleanness, tongue cleanness and malodor index was assessed by professional researcher. Tongue cleaner-equipped manual toothbrush was given to each subject with proper toothbrushing instruction. After 1 month passed, self assessment and researcher assessment regarding the same index were performed and analyzed statistically by chi-square test. Results: At 1st visit subjects seem to ignore tongue cleansing and showed poor tooth cleanness index, tongue cleanness index and malodor index, however the same subjects were motivated to clean their tongue and teeth and presented statistically improved distribution pattern in tooth cleanness index, tongue cleanness index and malodor index after using tongue cleaner-equipped manual toothbrush(p<0.01). Satisfaction to tongue cleaner-equipped manual toothbrush was 98%. Conclusion: Tongue cleaner-equipped manual toothbrush would be an effective tool for maintaining good oral hygiene through improving tooth and tongue cleanness and preventing malodor formation.
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친환경축산에 앞장서는 생균제 산업 - 사료용 생균제의 개발 및 이용 현황
김태일,Kim, Tae-Il 한국단미사료협회 2004 사료산업 Vol.2 No.6
현대는 인간의 복지와 환경보호의 양면을 중요하게 여기는 시대이다. 생물을 담보로 생산성을 추구하는 모든 산업이 환경에 친화적이면서 인간복지에 기여하는 산업으로 접목되기를 강요하고 있는 시대다. 이러한 현상은 범세계적인 추세다. 이러한 대전제에 부응한 산업이 되었을 때 얻게되는 수익에서 수익의 합리성을 찾을 수 있고 지속적인 성장이 기대되는 산업으로 보장받을 수 있기 때문인 것으로 생각된다. (중략)
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