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건강도시 가입지역의 가입 이후 시기변화에 따른 자신의 건강상태 영향 요인의 변화 연구
김윤환 보건의료산업학회 2024 보건의료산업학회지 Vol.18 No.1
Objectives: This study aimed to analyze the influencing factors and changes in the influencing factors on individuals’ health status in the period after joining the Healthy City region, focusing on metropolitan areas. Methods: Data were obtained from the 2012, 2015, and 2020 Seoul survey of household member for Yongsan-gu and Gwanak-gu, which have joined Healthy Cities since 2010. Difference tests and multiple regression analyses were performed to analyze the differences in variables according to the period in each region, and the factors influencing health status according to period changes. Results: In Yongsan-gu and Gwanak-gu, the social life happiness index, financial status happiness index, and relationship/friend relationship happiness index had a positive(+) influence at all times in both regions. In addition, even during the same period, some variables differed according to time changes within a region. Conclusions: Even if individuals joined a healthy city in the same period, there were differences in the factors affecting health status according to region period. There were also within-region according to the period. Therefore, it is necessary to promote Healthy City projects by considering the health of residents.
김윤환 가톨릭중앙의료원 가톨릭암센터 1996 암심포지움 Vol.- No.1
간암의 조기 진단방안으로 초음파를 당연히 이용하여야 하며, 이 검사는 전처치가 필요하지 않으며, 타검사에 비해 저렴한 가격으로 간암을 조기발견하는데 크게 기여를 할수 있다. 그러나. B형 및 C형 간염 바이러스 보균자중 고위험군에서는 정기적 초음파 검사와 더불어 CT를 반드시 1년에 한번이상 시행하여야 하며, 따라서 진단율에 있어 CT에 비해 상대적으로 낮은 초음파검사의 민감도를 극복할수 있다고 사료된다.
김윤환,Tae Hyeong Kim,Min Soo Kang,Jin-Ok Ahn,Jung Hoon Choi,Jin-Young Chung 대한수의학회 2020 Journal of Veterinary Science Vol.21 No.4
Background: Atopic dermatitis (AD) is a common chronic inflammatory skin disease. To understand AD, there have been many trials establishing AD animal models. Although various trials to establish AD animal models have been existed, even the mechanisms of AD in animal models are not enough clarified. Objectives: This study assessed AD characteristics induced in Nishiki-nezumi Cinnamon/Nagoya (Nc/Nga) mice following trinitrochlorobenzene (TNCB) treatment for different periods and house dust mite (HDM) treatment to compare each model's immunological patterns, especially with cytokine antibody array tool. Methods: In this study, we exposed Nc/Nga mice to TNCB or HDM extract to induce AD. Nc/Nga mice were divided into 4 groups: control, TNCB 2 weeks-treated, TNCB 8 weeks-treated, and HDM-treated groups. After AD induction, all mice were evaluated by serum immunoglobulin E (IgE) concentration and serum cytokine antibody assays, scoring of skin lesions, scoring of scratching frequency, and histological analysis. Results: The results showed significant differences between groups in serum IgE concentration, skin lesion scores, and scratching frequency. The analysis results for serum cytokine antibody arrays showed that in the TNCB 8 weeks- and HDM-treated groups, but not in the TNCB 2 weeks-treated group, expressions of genes related to the immune response were enriched. Among the histological results, the skin lesions in the HDM-treated group were most similar to those of AD. Conclusions: We confirmed that immunological pattern of AD mice was markedly different between HDM and TNCB treated groups. In addition, the immunological pattern was quietly different dependent on TNCB treated duration.