가로경관 요소가 도시 활력에 미치는 영향 -서울시를 대상으로-

김규엽,이창근 한국기초조형학회 2024 기초조형학연구 Vol.25 No.6

The purpose of this study is to focus on urban vitality and streetscapes in order to revitalize declining cities and to analyze the relationship between streetscape elements and their effects on urban vitality. To this end, we performed correlation analysis and GIS spatial analysis applying the residential neighborhood unit and face block unit of neighborhood theory targeting Seoul City, selected streetscape variables with significant influence, and derived and visualized regions through cartogram analysis. Summarizing the analysis results, 1)In residential neighborhoods, street networks and development intensity had a significant impact on urban vitality. In particular, in the case of street networks, this suggests that there is a need to create a pleasant walking environment by shortening the length of blocks within the street to encourage pedestrians to pass between each block. 2)For face blocks, network, building age, and development intensity were found to have significant effects. As for the street network, it has been analyzed that as the length of sidewalks per area increases, urban vitality increases, so it is necessary to improve the pedestrian environment by expanding sidewalks. In the case of average building age, unlike the results of previous studies, in Korea, the more old buildings are concentrated, the more likely it is to be an underdeveloped area, which can lead to a decrease in urban vitality. Therefore, we should induce a strategy to increase urban vitality through redevelopment and regeneration projects, and consider ways to plan for harmony with surrounding new buildings centered on old buildings with high historical value and preservation value. Based on these analysis results, it is necessary to introduce GPS technology in the future and use real street floating population data and advanced statistical analysis techniques to analyze in detail the impact of streetscape on urban vitality. It is believed that it will be a better study if landscape elements that increase urban vitality are derived using various cities as examples.

도시공간의 장소성이 도시 활력에 미치는 영향 -서울특별시를 대상으로-

김규엽,홍지수 한국기초조형학회 2025 기초조형학연구 Vol.26 No.1

본 연구는 도시공간의 물리적 환경의 쇠퇴와 함께 인구감소, 고령화, 공동체 기능 붕괴 등의 도시문제를 해결하기 위해 도시의 공공공간과 도시 활력 간의 관계를 분석하고자 하였다. 도시공간의 장소성 요인이 도시 활력에 미치는 영향을 파악하는데 연구의 목적이 있다. 이를 위해 장소성 요인은 도시형태, 도시이미지, 접근성 유형으로 분류하고, 각 유형은 근린이론을 근거로 한 근린 규모별로 영향을 분석하였다. 연구의 대상지는 도시개발밀도 및 토지이용 혼합도가 높고 대중교통 시스템이 발달하여 도시 활력 이론의 검증에 적합한 서울특별시로 선정하였다. 서울특별시를 대상으로 페이스 블록, 주거 근린, 제도적 근린 단위로 분류된 근린 규모별 GIS 공간 매핑 및 중첩을 통해 분석을 진행한 결과는 다음과 같다. 1)도시형태는 제도적 근린(행정구) 단위에 속하며 토지피복의 집적율을 나타내는 CONTAG 지수는 중구, 동대문구에서 가장 높게 나타났으며, 토지피복의 다양성을 나타내는 SIDI 지수는 생활인구 밀도와 음의 상관관계를 가짐으로써 너무 다양한 토지피복이나 경관 분포는 오히려 도시 활력에 역효과를 낼 수 있음을 알 수 있었다. SIDI 지수의 영향이 높은 지역으로는 중구, 동대문구, 양천구, 구로구, 금천구, 동작구로 나타났다. 2)접근성은 페이스 블록(집계구) 단위에 속하며 가까운 지하철과의 거리 및 면적당 버스정류소 개수가 있는데 두 변수는 생활인구 밀도와 유의한 상관관계가 나타나지 않았다. 3)도시이미지의 경우 제도적 근린(행정구) 단위의 생활인구 밀도 데이터와 함께 분석하였고 랜드마크, 특정 장소, 공간 축으로 나누어 지오코딩 하였다. 강한 도시이미지로 도출된 행정구역은 강남, 명동, 홍대입구, 인사동, 여의도, 종로, 이태원으로 나타났고, 랜드마크는 서울시청과 동대문이 지역에 미치는 도시 활력에 대한 효과가 높았다. This study aimed to analyze the relationship between urban public space and urban vitality in order to solve urban problems such as population decline, aging, and collapse of community functions along with the decline of the physical environment of urban space. The purpose of this study is to identify the influence of the spatial factors of urban space on urban vitality. For this purpose, place factors were classified into urban form, urban image, and accessibility types. The impact of each type was analyzed according to neighborhood size based on neighborhood theory. The results of the analysis conducted through GIS spatial mapping and overlay by neighborhood scale classified into face blocks, residential neighborhoods, and institutional neighborhood units for Seoul Metropolitan City are as follows. 1)The urban form belongs to the institutional neighborhood (administrative district) unit, and the CONTAG index, which indicates the concentration ratio of land cover, was highest in Jung-gu and Dongdaemun-gu. The SIDI index, which indicates land cover diversity, had a negative correlation with living population density. Therefore, it was found that overly diverse land cover or landscape distribution can have an adverse effect on urban vitality. Areas with a high impact on the SIDI index were Jung-gu, Dongdaemun-gu, Yangcheon-gu, Guro-gu, Geumcheon-gu, and Dongjak-gu. 2) Accessibility belongs to the face block (aggregation district) unit and includes distance to the nearest subway and number of bus stops per area. However, the two variables did not show a significant correlation with living population density. 3) In the case of the city image, it was analyzed together with the living population density data at the institutional neighborhood (administrative district) unit and geocoded by dividing it into landmarks, specific places, and spatial axes. Administrative districts with a strong city image were Gangnam, Myeongdong, Hongik University Entrance, Insa-dong, Yeouido, Jongno, and Itaewon. Landmarks such as Seoul City Hall and Dongdaemun had a high effect on urban vitality in the region.

해수중 콘크리트 기둥의 열화 및 보강성능해석

김규엽(Kim, Kyoo Yup),송하원(Song, Ha Won),변근주(Byun, Keun Joo) 한국콘크리트학회 2001 한국콘크리트학회 학술대회 논문집 Vol.2001 No.11

韓國正常女兒의 風疹抗體價에 關한 疫學的 調査硏究

金圭燁,李興在,李謹洙 한양대학교 의과대학 1982 한양의대 학술지 Vol.2 No.1

Because the rubella is usually an uncomplicated self-limiting disease, it is often ignored by physician. However viral replication in lymphnodes results in viremia, which may cross the placenta and infect the retus in pregnant female, giving rise to the fetus with congenital rubella syndrome. In order to prevent congenital rubella syndrome, the attenuated virus vaccine have been developed and widely used. Today, the routine veccination of rubella has become a subject of dispute among physicians in Korea. To get the exact data for rubella antibodies among Korea female, the author has made a survey for positive rate of H-I antibodies against Rubella. The results were follows: 1. Rubella antibody positive rate of below 2 years of age and 3 year were 30.0%, 40,0% respectively and tant of 11 years and 12 years were 70.0%, 66.6% respectively. 2. There was a tendency to show proportionaly increasing positive rate in accordance with the increasing age until 7 years. 3. However the positive rate among 8 years to 12 years groups showed no definite increasing tendency with the increasing age. 4. Over all positive rate of 107 girls were 50.5%. 5. Judging from above data, the positive rate of child bearing age group might not be more than 70.0% in Korea. 6. The author could propose the rubella vaccination should be included in the routine vaccination schedule for Korean children.

Genetic Analysis of Medicinal Plants in Curcumae Longae Rhizoma Using DNA Markers

Kyu Yeob Kim(김규엽),Min Kyeoung Kim(김민경),Na Rae Kim(김나래),Nam Ju Lim(임남주),Jong Hwan Kim(김종환),Ju Hye Kang(강주혜) 한국약용작물학회 2018 한국약용작물학회 학술대회논문집 Vol.2018 No.2

DNA 분석을 이용한 감국 유전자 마커 개발

김민경,김규엽,김나래,임남주,김종환,강주혜 한국약용작물학회 2018 한국약용작물학술대회 발표집 Vol.2018 No.10

Background : Chrysanthemi Indici Flos (甘菊) is listed in 「The Korea Herbal Pharmacopoeia (KHP)」as the original plant of Chrysanthemum indicum L. C. indicum was one of the most representative medicinal plants in Asteraceae, Dried flowers of this plant have been valid chemical composition such as flavonoids, phenylpropanoids, terpenoids, and polysaccharides, possessing broad spectrum antibacterial, antiviral, antihypertensive and anti-oxidation functions. Meanwhile, C. indicum was a polymorphic species, its morphological characteristics showed great diversity due to the different geographical and environmental factors. For this reason, there was conducted to develop molecular markers to distinguishing these C. indicum with C. morifolium, C. zawadskii var. latilobum and Aster spathulifolius by using conventional polymerase chain reaction (PCR). Methods and Results : In this study, In order to clearly identify origin of Chrysanthemi Indici Flos, these samples (C. indicum, C. morifolium, C. zawadskii var. latilobum and A. spathulifolius) were analyzed from five barcoding regions of chloroplast DNA (rbcL, matK, rpoB, atpF-atpH) and nuclear ribosomal DNA (ITS2) to evaluate the ability of discrimination for each barcoding region. Based on genetic distance, the percent of variable sites were provided the highest ITS2 value (56.9%), followed by atpF-atpH (48.18%), matK (27.2%), psbK (8.2%), and rbcL (2.9%). Comparative analysis based on the complete genome sequence of the petL-petG region INDEL (insertion/deletion) that the gene annotations were registered to the GenBank (accession number: JN-867592.1, NC-020092.1, MF-034027.1, NF-279514.1). Conclusion : From the above results, we may suggest that the petL-petG region INDEL analysis were conducted for molecular authentication of four plants (C. indicum, C. morifolium, C. zawadskii var. latilobum and A. spathulifolius). The findings of results indicated that petL-petG region might be established INDEL analysis systems and hence were proved to be an effective tools for molecular evaluation and comparison of “Chrysanthemi Indici Flos” with other plants.

Evidence of hydrolyzed traditional Korean red ginseng by malted barley on activation of receptor interacting proteins 2 and IkappaB kinase-beta in mouse peritoneal macrophages

임홍균,김규엽,문필동 셀메드 세포교정의약학회 2012 셀메드 (CellMed) Vol.2 No.3

Red ginseng, which has a variety of biological and pharmacological activities including antioxidant, anti-inflammatory, antimutagenic and anticarcinogenic effects, has been used for thousands of years as a general tonic in traditional oriental medicine. Here, we tested the immune regulatory activities of hydrolyzed red ginseng by malted barley (HRG) on the expressions of receptor interacting proteins (Rip) 2 and IB kinase-β (IKK-β) in mouse peritoneal macrophages. We show that HRG increased the activations of Rip 2 and IKK-β for the first time. When HRG was used in combination with recombinant interferon-γ (rIFN-γ), there was a marked cooperative induction of nitric oxide (NO) production. The increased expression of inducible NO synthase from rIFN-γ plus HRG-stimulated cells was almost completely inhibited by pre-treatment with pyrrolidine dithiocarbamate (PDTC), an inhibitor of nuclear factor-B (NF-κB). In addition, the treatment of peritoneal macrophages with rIFN-γ plus HRG caused significant increases in tumor necrosis factor (TNF)-α mRNA expression and production. Because NO and TNF-α play an important role in the immune function and host defense, HRG treatment can modulate several aspects of the host defense mechanisms as a result of the stimulations of the inducible nitric oxide synthase and NF-B. In conclusion, our findings demonstrate that HRG increases the productions of NO and TNF-α from rIFN-γ-primed macrophages and suggest that Rip2/IKK-β plays a critical role in mediating these immune regulatory effects of HRG.

DNA 분자마커를 이용한 강황의 종 감별

김민경,김규엽,김나래,임남주,김종환,강주혜 한국약용작물학회 2018 한국약용작물학술대회 발표집 Vol.2018 No.10

Background : Curcumae Longae Rhizoma (薑黃) is listed in「The Korea Pharmacopoeia (K P)」as the original plant of Curcuma longa L (Zingiberaceae). Meanwhile, Zeodariae Rhizoma (莪朮) is listed in 「The Korea Pharmacopoeia (KP)」as the original plant of C. phaeocaulis, C. aromatica and C. Kwangsiensi (Zingiberaceae). Due to the morphological similarities of the dried roots of this plant to those of C. phaeocaulis, C. aromatica and C. Kwangsiensis which is used as a substitute herbal for C.longa, distinguish these four species is extremely difficult. Methods and Results : A total of 90 collected samples were used in this study, In order to clearly distinguish of Curcumae Longae Rhizoma and Zeodariae Rhizoma were analysis based on sequence of the chloroplast DNA (trnK, rbcL, trnL-F, atpB-rbcL) and nuclear ribosomal DNA (ITS2). The present study aimed to analyze the percent of variable sites were provided the highest trnK (2.3%), in oder to develop a species-specific primer that can distinguish C.longa form C. phaeocaulis, C. aromatica and C. Kwangsiensis. In addition, the complete chloroplast genome of C. longa were sequenced by a 454 sequencing platform, and the structure of the obtained chloroplast genome was also analyzed. the result used that INDEL (insertion/deletion) marker for distinguish C.longa form C. phaeocaulis, C. aromatica and C. Kwangsiensis. Conclusion : The INDEL markers were developed based on the divergence of each sequence, and it is possible now to identify the four species of Curcumae Longae Rhizoma with just a single performance of PCR. This will not only prevent misused of the plant, but also to maintain the quality of the herbal medicine as well as to verify and guarantee safety for public health.

Validation of Analytical Methods for Polycyclic Aromatic Hydrocarbons in Herbal Medicine using GC-MS/MS

한초연,류다연,김규엽,이호연,이철현,박좌행,조수열 한국분석과학회 2022 학술대회논문집 Vol.2022 No.11

Validation of Analytical Methods for Polycyclic Aromatic Hydrocarbons in Herbal Medicine

류다연,한초연,김규엽,이호연,이철현,박좌행,조수열 한국분석과학회 2022 학술대회논문집 Vol.2022 No.11