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F-18 FDG PET/CT에서 양성과 악성 근골격 종양의 감별진단-수신자 판단특성곡선을 이용한 maxSUV의 절단값 결정
공은정 ( Eun Jung Kong ),조인호 ( Ihn Ho Cho ),천경아 ( Kyung Ah Chun ),원규장 ( Kyu Chang Won ),이형우 ( Hyung Woo Lee ),최준혁 ( Jun Heok Choi ),신덕섭 ( Duk Seop Shin ) 대한핵의학회 2007 핵의학 분자영상 Vol.41 No.6
Purpose: We evaluated the standard uptake value (SUV) of F-18 FDG at PET/CT for differentiation of benign from malignant tumor in primary musculoskeletal tumors. Materials and Methods: Forty-six tumors (11 benign and 12 malignant soft tissue tumors, 9 benign and 14 malignant bone tumors) were examined with F-18 FDG PET/CT (Discovery ST, GE) prior to tissue diagnosis. The maxSUV(maximum value of SUV) were calculated and compared between benign and malignant lesions. The lesion analysis was based on the transverse whole body image. The maxSUV with cutoff of 4.1 was used in distinguishing benign from malignant soft tissue tumor and 3.05 was used in 0bone tumor by ROC curve. Results: There was a statistically significant difference in maxSUV between benign (n=11; maxSUV 3.4±3.2) and malignant (n=12; maxSUV 14.8±12.2) lesions in soft tissue tumor (p=0.001). Between benign bone tumor (n=9; maxSUV 5.4±4.0) and malignant bone tumor (n=14; maxSUV 7.3±3.2), there was not a significant difference in maxSUV. The sensitivity and specificity for differentiating malignant from benign soft tissue tumor was 83% and 91%, respectively. There were four false positive malignant bone tumor cases to include fibrous dysplasia, Langerhans-cell histiocytosis (n=2) and osteoid osteoma. Also, one false positive case of malignant soft tissue tumor was nodular fasciitis. Conclusion: The maxSUV was useful for differentiation of benign from malignant lesion in primary soft tissue tumors. In bone tumor, the low maxSUV correlated well with benign lesions but high maxSUV did not always mean malignancy. (Nucl Med Mol Imaging 2007;41(6):553-560)
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흥미영상 : (18)F-FDG PET/CT로 진단된 충수 선암종
공은정 ( Eun Jung Kong ),조인호 ( Ihn Ho Cho ),천경아 ( Kyung Ah Chun ),원규장 ( Kyu Chang Won ),이형우 ( Hyung Woo Lee ),김홍진 ( Hong Jin Kim ) 대한핵의학회 2006 핵의학 분자영상 Vol.40 No.3
A 53-year-old man underwent (18)F-FDG whole body PET/CT because of the detected liver mass on abdominal CT. The PET/CT showed a huge liver mass (9×9㎝, SUV: 12.12) in the right lobe and a focally hypermetabolic lesion in the right lower quadrant of abdomen (SUV: 9.12). At first, we suspected that the focal hypermetabolic lesion in RLQ was the physiologic uptake of ureter or a metastatic lesion of small bowel. We repeated the abdominal PET/CT next day. The focally hypermetabolic lesion was identified as the appendiceal mass. He underwent right hemicolectomy and right lobectomy of the liver. It was confirmed that the lesion was appendiceal adenocarcinoma with liver metastasis. Cancer of the appendix is an uncommon disease that is rarely suspected before surgery. But, we suggest that PET/CT is useful to identify the small lesion like appendiceal malignant mass. (Nucl Med Mol Imaging 2006;40(3):188-189)
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영어 문장 처리 과정에서의 의미 정보 및 운율 단서 활용도의 상관성 연구
강선미(Kang, Sun-mi),공은정(Kong, Eun-jong) 한국영어학학회 2018 영어학연구 Vol.24 No.1
This study explored the perceptual sensitivity to the prosodic and semantic cues in disambiguating the structurally ambiguous sentences by English native speakers and Korean learners of English. The cross-modal task was conducted to investigate whether/how the two groups of listeners utilized the prosodic information (i.e., boundary tones) when the semantic biases (i.e., subject-and object-bias) resolved structural ambiguity. The results showed that the native speakers reacted sensitively to both the semantic and the prosodic cues while the Korean learners of English were only sensitive to the semantic information. The current findings suggest that the speakers with limited control of the language are poor at utilizing redundant phonetic information faced with resolving linguistic ambiguity.
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