인천지역의 B 형 간염에 관한 혈청역학적 연구

강진경 ( Jin Kyung Kang ),장경문 ( K. M. Jang ),우성희 ( S. H. Woo ),윤동현 ( D. H. Yun ),이광래 ( K. R. Lee ),권용오 ( Y. O. Kwon ),태경희 ( K. H. Tai ),문영주 ( Y. J. Moon ),변기수 ( G. S. Byun ) 대한내과학회 1983 대한내과학회지 Vol.26 No.12

백서의 허혈성 위손상에 대한 Misoprosto1의 위점막 보호 효과

강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),박인서(In Suh Park),문영명(Young Myoung Moon),이상인(Sang In Lee),이동기(Dong Ki Lee),함기백(Ki Baik Hahm) 대한소화기학회 1990 대한소화기학회지 Vol.22 No.1

A study was undertaken to unvestigate the rele of prostaglandin E. ( misprostol) on the protective effect of the ischemic and/or acldic mucosal amage in rat stomack using a electrophysiolgic method. The result were as follows.1) A significant graded reduction of potential difference was noted after the blood withdrawal.2) The intragastric instillation of NaHCos did not attenuate the PD decline produced by the blood withdrawal and the PD decline was aggravated after the intragastric instillation of 0.1 NHCl 3) Misoprostol pretreatment tended to suppress the PD decline produced by the ischemia and/or acid gastric injury.4) Sudden potential drop was noted in the blood withdrawal with acidic gastric injury group, however, it was hot observed in the misoprostol pretreatment group. 5) The blood withdrawal did not induce the grow and microscopic lesions in the stomach in the absence of exogenous acid, in spite of a reduction in nofantial difference. In conclusion, Prostaglanding it seems to play a role in attenuating the potaneal difference decline caused by the iachemia and/or acid gastric injury, that is, cytoprotecting from gastrin mucosal damege.

간암환자에 있어서 Doppler 초음파 검사로 진단된 간내 동맥 - 문맥루

강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),김원호(Won Ho Kim),정재복(Jae Bock Chungj),안광진(Kwang Jin Ahn) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.3

Doppler ultrasonography, which provides noninvasive evaluation of bloodflow patterns has used widely in cardiovascular diseases. Recently intratumoral Doppler signal has been analysed to evalu- ate intra and peritumoral blood flow and to differentiate malignant from benign neoplasm. Hepatocellular carcinomas have characteristic vascular appearance including arteriovenous shunts that aid in their diagnosis and Doppler ultrasonography allows recognition of these arteriovenous shunts. But Doppler ultrasonographic observation of arterio-portal fistula involving relatively large branch of portal vein is very rare. We present a 55-year-o)d female patient with hepatoce)lular carcinoma showing characteristic L)oppler signal consistant with intrahepatic arterio-portal fistula which was confirmed by hepatic arteriography. After transarterial embolization with Gelfoam this high velocity flow signal was clisappeared.

췌장의 유두상 낭성종양

강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),김원호(Won Ho Kim),홍성표(Sung Pyo Hong),노성훈(Sung Hun Noh),신동환(Dong Hwan Shin) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.2

Papillary cystic neoplasm of the pancreas is a rare low-grade malignant tumor which occurs chiefly in young women. It is also designated as a solid and papillary epithelial neoplasm of the pancreas because of its distinctive microscopic features, that is, papillary areas composed of layers of tall cells situated on fibrovascular stalks and solid areas consisting of sheets of cells with interspersed areas of cystic degeneration. Since the prognosis for this lesion is much more favorable than for any other pancreatic neoplasm due to its rare metastasis and recurrence rate, preoperative suspicion and correct diagnosis are important for this unusual and potentially curable tumor. We present a 22-year-old female patient with a papillary-cystic neoplasrn of the pancreas who complained of left upper quadrant abdominal pain. Ultrasonography demonstrated a large, partly cystic tumor in the pancreatic tail and abdominal cornputed tomography disclosed a well-defined solid and cystic mass. On celiac arteriography, the splenic artery and superior mensenteric artery were displaced by the tumor, and no tumor vessel was seen. ERCP showed displacement of the main pancreatic duct and absence of ductal branches in the mass area. The tumor was totally excised with the attached spl en and a small portion of the adherent distal pancreas on the 13th. Hospital day.

막성 (膜性) Budd - Chiari 증후군의 (症候群) 경피적 (經皮的) 혈관성형술 (血管成形術)

강진경(Jin Kyung Kang),김기황(Ki Whang Kim),최규옥(Kyu Ok Choe),김응(Eung Kim),조범구(Bum Koo Cho) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.2

The author report a case of membraneous type of Budd-Chiari Syndrome which was treated by percutaneous transluminal angioplasty. After procedure, there showed no pressure gradient between RA and IVC. Collateral circulations through left renal and paravertebral vein were disappeared. Clinically, abdominal wall venous collaterals was also disappeared. Percutaneous transluminal angiop1asty will be a promising method in the treatment of membraneous type of Budd-Chiari Syndrome.

식도 (食道) 편평유두종 (扁平乳頭腫) 2예

강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),박인서(In Suh Park),문영명(Young Myoung Moon),이상인(Sang In Lee),전재윤(Chae Yoon Chon),김원호(Won Ho Kim),박찬일(Chan Il Park),이강석(Kang Suk Lee),이광길(Kwang Kill Lee) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.1

Benign tumors of esophagus arising either from mucosa or submucosa are rare pathological entities. Of the benign esophageal tumor, squamous papilloma is a distinct rare pathological peculiarity recently reported with increased frequency, giving no symptoms during life and discovered unusually and in cidentally during autopsy. Morphologically, squamous papilloma of the esophagus was benign sessile lesions of surface epithelium characteristically composed of finger-like projections of tissue lined by increased numbers of squamous cells and having cores of fibrovascular tissue. Although the etiology of squamous papilloma of esophagus remains uncertain, the most convincing etiology of humans remains chronic irritation from gastric acid reflux. Squamous papilloma of the esophagus have not been shown to be premalignant. They should be removed completely so that coexisting malignant conditions are not overlooked. Recently we had the opportunity to observe two cases of histologically demonstrated squamous papilloma of the esophagus. Our purpose here is to report these patients and to review the literatures.

한국인 간질환 (肝疾患) 환자의 B 형 간염 (肝炎) 바이러스 표식자 (標識子) 양성율에 (陽성율) 관한 연구

강진경(Jin Kyung Kang),최흥재(Heung Jae Choi),박인서(In Suh Park),문영명(Young Myoung Moon),이상인(Sang In Lee),김영수(Young Soo Kim),박규숙(Kye Sook Park) 대한소화기학회 1983 대한소화기학회지 Vol.15 No.2

N/A Authors carried out studies to determine the frequency of Hepatitis B virus markers in the serum of 3450 patients with liver diseases, who were diagnosed by clinically, biochemically, serologically and morphologically from September 1977 to August 1982 at Severance hospital, Yonsei University Medical College. The hepatitis B virus markers were measured by method of solid phase radioimmunoassay technique. The results obtained were summarized as follows. The positivity of HBsAg was 78. 9, in chronic active hepatitis, 68.4% in hepatoma, 60.1% in liver cirrhosis, 55.8% in chronic persistent hepatitis, 47.9% In chronic hepatitis, 45.7% in acute viral hepatitis, 37.9% in fulminant hepatitis. The overall positivity of patients with liver diseases was 54.6%. 2) The positivity of anti-HBs was 46.2% in fulminant hepatitis, 33.6% in chronic hepatitis, 27.0% in liver cirrhosis, 21.3% in hepatoma, 20.0% in chronic persistent hepatitis, 18.3% in acute viral hepatitis, 16.3% in chronic active hepatitis. 3) The positivity of anti-HBc was 100.0% in fulminant and chronic persistent hepatitis, 97.8% in chronic active hepatitis, 97. 6% in hepatoma, 88. 2%. In liver cirrhosis, 87% in chronic hepatitis, 74. 6% in acute viral hepatitis. 4) The positivity of HBeAg was 61.1% in chronic active hepatitis, 50.0% in fulminant hepatitis, 44. 6% in acute viral hepatitis, 38. 1% in chronic hepatitis, 37. 5% in chronic persistent hepatitis, 36.0% in liver cirrhosis, 20.2% in hepatoma. 5) The positivity of anti-Hbe was 66. 7% in fulminant hepatitis, 60. 0% in hepatoma, 48.0% in liver cirrhosis, 35.1% chronic active hepatitis, 33.3% in chronic persistent hepatitis, 29.4% in chronic hepatitis, 20.3% in acute viral hepatitis. 6) The detection rate of one or more markers among HBsAg, anti-HBs, anti-HBc in patients with liver diseases was 84.1%. And the most frequent distribution pattern of 5 hepatitis B viral markers was HBsAg(+), anti-HBc(+), anti-HBs( ), HBeAg(+), anti-HBe( ) in acute and chronic hepatitis, HBsAg(+), anti-HBc(+), anti-HBs( ), HBeAg( ), anti-HBe (+) in liver cirrhosis and hepatoma.

마이크로컴퓨터에 의한 소화기내시경 검사의 정보처리

강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),김경희(Kyung Hee Kim),이원영(Won Young Lee) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.1

N/A The availability of low cost and reasonably capable micro-computer system is affecting many areas of activity. We describe our experience with the development of a micro-computer data management system for the data generated by our gastrointestinal endoscopic practice. The system is based on a APPLE II PLUS micro-computer, disk drive, Korean Word R.O.M. Card and printer combination. The programs for this system were commercially available programs for data base and were edited for their characteristics of various endoscopic studies. The system has the following attributes: 1) It is relatively inexpensive. 2) It is physically small and is located in our endoscopy unit. 3) The programming is designed to facilitate rapid entry of data. 4) A print-out of each patients examination as well as a record in the disk memory is generated. 5) Information from the disk memory file can be retrieved according to patient record number or diagnostic category. 6) Sorting of the data can be performed according to two or more diagnostic criteria. Thus, the system enhance the ability to retrospectively review large amounts of patient data. The relatively low cost and small size of the equipment facilitate its use in a wide variety of endoscopy practice.

초음파진단을 (超音波診斷) 이용한 한국인 정상췌장 (正常膵臟) 크기에 관한 연구

강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),박인서(In Suh Park),문영명(Young Myong Moon),이상인(Sang In Lee) 대한소화기학회 1981 대한소화기학회지 Vol.13 No.2

N/A It is difficult to examine the pancreas by routine roentgenographic methods, radioisotopic scanning and angiography. The ultrasonography has proved to be an useful tool in the evaluation of pancreatic diseases. Determination of the normal size and contour of the pancreas is important. We performed ultrasonography in 89 subjects with normal pancreas and the results were reviewed. 1 Successful ultrasonograms of normal pancreas were obtained in 84 among 89 subjects examined, being 94.4po of success rate The shapes of pancreas were dumhhell shape in 47 of 84 cases(55. 9%), sausage shape in (29.8%) tadpole shape in 11(13. 1%), and reversed tadpole shape in 1 case. 3.The pancreatic head was 1.8+-0.38cm in the mean thickness(range: l. 0-2. 9cm), the neck l. 1+- 0. 41 cm (range: 0. 4-2. 0 cm), and the body 1. 8+-0. 37 cm (range: l. 0-2. 6 cm).

간장 및 담도 : 생검으로 확진된 지방간의 임상적 고찰

강진경(Jin Kyung Kang),최흥재(Heung Jae Choi),전재윤(Chae Yoon Chon),박찬일(Chan Il Park),윤정한(Jung Han Yoon),임대순(Dae Soon Yim) 대한소화기학회 1986 대한소화기학회지 Vol.18 No.1

N/A Fatty liver is caused by derangement of fat metabolism and can be reversed by removal of contributing factors. The contributing factors of fatty liver include overweight, chronic alcoholism, diabetes mellitus, malnutrition, and drug abuse such as tetracycline. In this study, age and sex distribution, contributing factors, clinical features, liver function tests, correlation of grade of fatty liver to body weight, liver function test and viral markers were reviewed. Clinical diagnosis, peritoneoscopic diagnosis, and pathologic findings were compared in 54 cases with fatty liver proven by peritoneoscopic liver biopsy who were admitted to Yonsei University Severance Hospital from January 1981 to June 1985. The following results were obtained. 1) The mean age of 54 cases was 39. 9 years and the male to female ratio was 2.9 to 1 2) Contributing factors of fatty liver were overweight in 27 cases(50.0%), chronic alcoh- olism in 23 cases(42.5%), diabetes mellitus in 8 cases(14.9%), and malnutrition in 1 case (1 .9%). Overweight was the only contributing factor in 13 cases(24.o%), chronic alcoholism only in 12 cases(22.2%) There were more than one contributing factors in 16 cases(29.7%) and no definite contributing factors in 12 cases(22.2%). 3) Easy fatigability was the most frequent symptom which was found in 28 cases(52.7%) and hepatomegaly was the most common physical finding which was found in 26 cases (48.6%). 4) The r-GTP level was increased in 43 cases(80%), SGOT in 35 cases(65.5%), SGPT in 40 cases(74.5%), and triglyceride in 37 cases(68.9%). 5) The r-GTP and SGOT level were more elevated with statistical significance in chronic alcoholic group than in overweight group. G) There were no correlations of grade of fatty liver to body weight and liver function tests. 7) Eleven cases(22.5%) of 49 cases were HBsAg positive which was significantly higher than that of normal population in Korea. 8) A clinical diagnosis prior to peritoneoscopy was chronic hepatitis in 34 cases(62.8%), alcoholic liver disease in 9 cases(16.7%), fatty liver in 5 cases(9.2%), and HBsAg carrier in 4 cases(7.5%) A peritoneoscopic diagnosis was fatty liver in 3l cases(57.4%), chronic hepatitis in 10 cases(18.5%), acute unresolved hepatitis in 5 cases(9.3%), and normal liver in 8 cases(14.8%). In summary, the clinical diagnosis of fatty liver was made only in 5 cases(9.2%), and peritoneoscopic diagnosis of fatty liver in 31 cases(57.4%). The majority of the rest was chronic hepatitis. Therefore, it is mandatory to perform liver biopsy to distinguish fatty liver from chronic hepatitis.