20~40대 여성의 식품 선호도가 피부변화에 미치는 영향

박재영,이명선 한국피부과학연구원 2013 대한피부미용학회지 Vol.11 No.2

A survey was conducted on 500 women who were in their 20s to 40s and resided in North Gyeongsang Province including Daegu and Pohang from August 1 to September 28, 2012. And the answer sheets from 485 respondents were analyzed. The questionnaire used in this study covered skin type, dietary habits, life habits and food preference. After six food groups were selected, their preference for the food groups were analyzed, and the foods were classified again into three according to their preference. By age, the women who were aged between 40 and 49 made up the largest age group(30.3%), followed by the 30-39 age group(29.7%), those under the age of 25(24.5%) and the 25-29 age group(15.5%). As for preference for cereals, the women who were under the age of 25 had the strongest preference for cereals, and those aged between 40 and 49 had a less liking for cereals than the other age groups. The younger women showed a more preference for bread and rice cake. The women who were aged between 25 and 29 had the biggest preference for meat, fish, milk, dairy products and beverages, and the older women had a greater liking for vegetables and fruit. Concerning the skin type of the women in their 20s to 40s, a combination skin was most common, followed by a dry skin, normal skin and oily skin. The women who had a combination skin preferred bread, rice cake, milk and dairy products. Regarding ways of improving the skin, the women who were under the age of 25 were more concerned about cleansing, and those who were aged between 30 and 39 were more careful about the choice of cosmetics. The women whose skin was sensitive preferred vegetables and fruit, and many of those who ate lots of meat had an oily skin. The women with a combination skin were fond of spicy food, and those with an acne skin liked sweet taste. Those who had an acne skin perceived that drinking exerted a great influence on the skin, and many of the women who ate a lot of food, four cups of water or more per day, had a combination skin. The findings of the study suggest that the health of the skin is closely bound up with diet, namely the choice of food, and that the choice of food exercises an influence on the change of the skin and the maintenance of beautiful skin.

연구논문 : 피부미용 교육 프로그램이 피부의 지식 및 피부 관리행위에 미치는 효과

정은숙 ( Eun Suk Jeong ),강수경 ( Soo Kyung Kang ) 한국미용학회 2007 한국미용학회지 Vol.13 No.3

This study grasped the effect of skin health education program on knowledge of skin and skin care act in college students. A lecture method using a moving picture was used with a moving picture was conducted and college students were selected as a subject. This study intended to provide fundamental materials needed to develop skin health education programs in the future and further, contribute to the improvement of skin health. The period of research was from Oct. 7th to 28th, 2004 and subjects included a test group of 101 students and a control group of 83 randomly selected in a college located in Gwangju city. Research instruments were made using Power Point with its focus on skin health related materials. To produce a moving picture, this author corrected and edited skin care materials broadcasted on KBS health program to fit for this study. The research procedure was pre-survey and post-survey after two weeks of education. The results are as follows. It was found that the correlation of skin-related features and several factors of skin health, and the skin health education program of test group had an effect on knowledge, and the changes of care act. Furthermore, the skin health education program between two groups showed that the test group had a significantly high effect in the awareness of care act. This study demonstrated that the skin health education program had an effect on knowledge, and act. Since a lecture method using a moving picture was more effective than a traditional method alone, this kind of new education method should be systematically established and spreaded.

두경부암 치료를 위한 6 MV X-선 산란판의 제작과 산란분포 측정

이경자(Kyung-Ja Lee),추성실(Sung Sil Chu) 대한방사선종양학회 1996 Radiation Oncology Journal Vol.14 No.4

목적 : 6 MV x-선의 선형가속기를 이용하여 두경부종양환자를 치료시에 피부표면의 종양에 균일한 선량을 부여하기 위하여 조직등가물질로 산란판을 제작하여 산란판의 두께와 위치에 따라 조직의 표면선량과 최대선량지점을 측정하였다. 방법 : 조직등가물질인 폴리스틸렌으로 산란판을 제작하여 가속기의 콜리메터와 피부사이에 부착하여 조사면, 산란판의 두께 및 피부와의 간격에 따라 피부표면 선량과 최대선량지점을 측정하여 측정결과는 최대선량 대 표면선량비(BUR-1)로 표시하였으며 불균등 표면보상에 사용하는 조직등가 볼러스에 의한 선량분포변화를 측정하여 산란판과 비교하였다. 결과 : 6 MV x-선 선형가속기와 피부사이에 산란판을 설치하여 피부선량이 증가되었으며 산란판의 위치에 따라 피부선량이 변화되었고 최대선량지점은 피부표면쪽으로 이동하였다. 최대 선량지점은 피부하 1.5cm 깊이에서 최대선량이 투여되고 피부쪽으로 선량이 급속히 감소되어 1 cm 두께의 산란판을 사용한 경우 피부간의 거리가 0, 5, 10, 15, 20 cm로 증가하였을때 최대 선량지점은 피부표면으로부터 5, 10.2, 12.3, 13.9, 14.8 mm로 증가되었다. 결론 : 6 MV x-선을 이용하여 두경부종양을 치료할 경우 산란판을 이용하여 이차산란전자를 피부표면 앞에서 발생시킴으로써 피부의 선량이 증가되어 최대선량지점은 피부표면으로 이동시킴으로써 종양부위에 균일한 선량을 부여시킬 수 있었다. Purpose : This study was performed for adequate irradiating tumor area when 6 MV linear accerelator photon was used to treat the head and neck tumor. The skin surface dose and maximum build-up region was measured by using a spiler which was located between skin surface and collimator. Methods : A spoiler was made of tissue equivalent material and the skin surface dose and maximum build-up region was measured varing with field size, thinkness of spoiler and interval between skin and collimator. The resulte of skin surface dose and maximum build-up dose was represented as a build -up ratio and it was compared with dose distribution by using a bolus Results : The skin surface dose was increased with appling spoiler and decreased by distance of the skin-spoiler separation. The maxium build-up region was 1.5 cm below the skin surface and it was markedly decreased near the skin surface. By using a 1.0-cm thinkness spoiler. Dmax moved to ,5, 10.2, 12.3, 13.9 and 14.8 mm from the skin surface by separation of the spoiler from the skin 0, 5, 10, 15, 20 cm, respectiveeiy. Conclusion : The skin surface dose was increased and maximum build-up region was moved to the surface by using a spoiler. Therefore spoiler was useful in treating by high energy photon in the head and neck tumor

P168 Survey on needs for skin health care mobile application

( Jeong Soo Kim ),( Seul Ki Lee ),( Ha Ryeong Ryu ),( Chul Hyun Yoon ),( Jin Ok Baek ),( Jong Rok Lee ),( Joo Young Roh ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.2

<div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div><div style="display:none">fiogf49gjkf0d</div> Background: Along with the trend of wellness, dermatology and skin care associated field is the most representative growing industry. Recently, there is a variety of health-care device and mobile phone applications were developed. However, application of health-care service is limited and the lack of reliability is a problem as well. Objectives: We considered the people’s needs of skin-health care mobile application and checked their intentional use of the application. Methods: 87 who were diagnosed as atopic dermatitis, allergic contact dermatitis and acne (26:29:32) in the dermatologic clinic were enrolled in the questionnaire survey,including items such as skin health care awareness and recognition, skin care type, and the intention of using skin health care mobile services. Results: 88% of respondent answered that they usually obtain information on skin problem through internet, while only 8% used mobile application. 62% answered that they have interest in the usage of new mobile application. The most common question people have was the cause of skin problem which accounted for 64.4%. Respondents assume the food/dietary habit as the main cause of skin problem (31%). They considered moist and elasticity of skin as top priority for good skin(48.3%). Conclusion: We could gathered data of skin health care mobile service with regards to consumers needs through this survey.Mobile health application might be supportive tool for the patients and dermatologist to prevent and educational purpose.

모녀간 피부 특성의 상관관계에 대한 연구

조가영 ( Ga Young Cho ),김지연 ( Jee Yeun Kim ),염명훈 ( Myeong Hun Yeom ),조준철 ( Jun Chul Cho ),김종일 ( Jong Il Kim ),김윤범 ( Yoon Bum Kim ) 대한한방부인과학회 2012 大韓韓方婦人科學會誌 Vol.25 No.4

Objectives: It is well known that genetic factors and environmental factors play major role in aging skin. In general, son and daughter take after their parents in appearance. But comparability of skin properties in Korean family has not been well estimated. So we evaluated the correlation of skin properties in Korean mother-daughter pairs. Methods: 10 couples of mother and daughter pair(n=20) participate in this study. Mothers and daughters were aged 50.6±2.459 and 23.8±2.15 years, respectively. Skin moisture, sebum, skin color and elasticity is measured using non-invasive method: Corneometer CM825, Sebumeter(MPA580), Mexameter MX18, Cutometer MPA580. Statistical analysis program we used is Minitab 14 Korea. Results: The Skin moisture of mother group was significantly higher than daughter group. And skin elasticity(R2) of the daughter group was significantly higher than mother group. In the results of correlation analysis between mother and daughter pairs, skin elasticity(R2) had high positive correlation(r=0.729, p=0.026). But skin moisture, sebum, melanin index, erythema index and skin elasticity(R5) did not be confirmed a significant correlation. Conclusions: Skin elasticity(R2) is the only factor that showed high positive correlation significantly in mother and daughter pairs. Mother and daughter share the genetic factors and environmental factors that influence skin aging. So, mother`s aging pattern will be a good guide for anti-aging of daughters.

사람피부와 돼지피부를 이용한 OECD Guideline 428에 따른 피부흡수시험법 검증

한주희 ( Ju Hee Han ),석승혁 ( Seung Hyeok Seok ),백민원 ( Min Won Baek ),김동재 ( Dong Jae Kim ),나이랑 ( Yi Rang Na ),박귀례 ( Kui Lea Park ),손경희 ( Kyung Hee Sohn ),주정흔 ( Jung Hun Ju ),임채형 ( Chae Hyung Lim ),박재학 ( Ja 한국동물실험대체법학회 2009 동물실험대체법학회지 Vol.3 No.1

In vitro skin absorption test has been proposed as a reliable alternative method to in vivo skin absorption test. In many other countries, in vitro skin absorption has been conducted according to OECD guideline which was adopted in 2000. However, in vitro skin absorption test hasn`t been validated yet in Korea. In this study, experimental conditions were set and validated according to a detailed protocol of OECD guideline 428. We compared penetration properties of caffeine (log P -0.01) and benzoic acid (log P 1.83) through human split-thickness skin and pig ear full-thickness skin using Franz cell. The permeation of caffeine through the human skin (10.16%) was higher than through pig ear full-thickness skin (1.68%). The permeation of benzoic acid through human skin and pig ear skin were similar. Hydrophilic caffeine penetrated the human split-thickness skin more efficiently than pig ear full-thickness skin. Our data showed a similar pattern with compared other reports that regarded skin absorption of caffeine and benzoic acid through split-thickness skin and full-thickness skin. In conclusion, we validated in vitro skin absorption test in Korea

Immediate regraft of the remnant skin on the donor site in split-thickness skin grafting

Park, Young Ji,Ryu, Woo Sang,Kim, Jun Oh,Kwon, Gyu Hyeon,Kim, Jun Sik,Kim, Nam Gyun,Lee, Kyung Suk Korean Cleft Palate-Craniofacial Association 2019 Archives of Craniofacial Surgery Vol.20 No.2

Background: Skin defects of head and neck need reconstruction using various local flaps. In some cases, surgeons should consider skin graft for large skin defect. It is important to heal skin graft and donor sites. The authors investigated wound healing mechanisms at the donor sites with split-thick-ness skin graft (STSG). In this study, the authors compared two types of immediate regraft including sheets and islands for the donor site after facial skin graft using remnant skin. Methods: The author reviewed 10 patients who underwent STSG, from March 2015 to May 2017, for skin defects in the craniofacial area. The donor site was immediately covered with the two types using remnant skin after harvesting skin onto the recipient site. Depending on the size of the remnant skin, we conducted regraft with the single sheet (n= 5) and island types (n= 5). Results: On postoperative day 1 and 3 months, the scar formation was evaluated using the Patient and Observer Scar Assessment Scale (POSAS) and Vancouver Scar Scale (VSS). Total POSAS and VSS scores for the island type were lower than in single sheet group after 3 months postoperatively. There was significant difference in specific categories of POSAS and VSS. Conclusion: This study showed a reduction in scar formation following immediate regrafting of the remnant skin at the donor site after STSG surgery. Particularly, the island type is useful for clinical application to facilitate healing of donor sites with STSG.

여대생의 피부유형에 따른 식생활습관 및 식품기호도

서동희,박금순,신영자 한국식생활문화학회 2005 韓國食生活文化學會誌 Vol.20 No.1

This study seeks to classify the skin types and determined the relation between the dietary habit and preference of foods targeting college women in Daegu and Gyeong-Buk Province. Skin types of the subjects were 31% of combination skin, 25% of dry skin and 22% of normal ? oily skin. College women mostly had two meals a day, and those who had less frequent meals developed more combination skin. Many of them did not exercise, and women with normal skin who did not exercise showed the lowest at 13.9%, supporting the significance (p〈.05). It was exposed that don't have breakfast and have irregular meal and don't have easy meal in all skin types. Instant foods was exposed that ingested the most in dry skin and the least in oily skin, supporting the significance(p〈.05) and fruit or vegetable ingested much in dry skin. It was exposed that considered atmosphere at meal and meal helps in health in all skin types, normal skin type considered balanced diets the most and supporting the significance(p〈.01) Food preference in all skin types showed the strongest in drinks and showed strong in greenish yellow vegetables, fruits, confectioneries, drinks, milk and dairy goods. On the other hand. it showed low in nuts and salted fishes. In sum, regular and balanced meals give the skin a healthy status. and intake of protein, vitamins and minerals has impact on the skin status. Thus. sufficient quality nutrition is crucial in staying a healthy skin.

Comparison of structural characteristics and molecular markers of rabbit skin, pig skin, and reconstructed human epidermis for an ex vivo human skin model

Uhm Chanyang,Jeong Haengdueng,Lee Su Hyon,Hwang Jae Sung,Lim Kyung-Min,Nam Ki Taek 한국독성학회 2023 Toxicological Research Vol.39 No.3

The Organization for Economic Co-operation and Development approved a reconstructed human epidermis (RHE) model for in vitro skin irritation and corrosion tests as an alternative to animal testing for cosmetics, which has been banned in the European Union since 2013. However, RHE models have several limitations, such as high manufacturing costs, a loose skin barrier, and inability to simulate all cellular and non-cellular components of the human epidermis. Therefore, new alternative skin models are needed. Ex vivo skin models have been suggested as promising tools. Here, we investigated the structural similarities in the epidermis of pig and rabbit skin, a commercial RHE model (Keraskin), and human skin. To compare the structural similarity, the thickness of each epidermal layer was compared using molecular markers. Among the candidate human skin surrogates, the epidermal thickness of the pig skin was the most similar to that of human skin, followed by rabbit skin and Keraskin. Keraskin showed thicker cornified and granular layers than human skin, while rabbit skin displayed thinner layers. Moreover, the proliferation indices of Keraskin and rabbit skin were higher than those of human skin, whereas the proliferation index of the pig skin was similar to that of human skin. Some or none of the human skin barrier proteins FLG, CLDN1, and CDH1 were expressed in pig and rabbit skin, whereas all human proteins were expressed in Keraskin. Collectively, we propose ex vivo pig skin as the most suitable model for skin irritation testing because of its similarity to human skin.

Characterization of Skin Permeation of Vitamin C : Theoretical Analysis of Penetration Profiles and Differential Scanning Calorimetry Study

Cho LEE, Ae-Ri,TOJO, Kakuji 德成女子大學校 藥學硏究所 1999 藥學論文誌 Vol.10 No.1

A mechanism for the relatively high permeability of vitamin C in relation to the change in the protein domain of the stratum corneum has been proposed. Firstly, the skin permeation characteristics of vitamin C (l-[1-^14C]-ascorbic acid) using whole skin and stripped skin of the hairless mouse were investigated. By employing a double layer model, physiochemical properties such as diffusivity and solubility of vitamin C in each skin layer, stratum corneum and viable skin were determined. Then, the high skin permeation rate of vitamin C was characterized. A differential scanning calorimetry, (DSC), study was employed to investigate the effect of vitamin C on the stratum corneum, a major diffusion barrier for the skin transport of the compound. Vitamin C was found to permeate rapidly through the skin, in spite of its low lipophilicity. The diffusivity determined from the lag-time was approximately 1000 times higher in the stripped skin, compared with whole skin. There is a dramatic increase (10-fold) in the permeation rate in stripped skin indicating the major barrier presented by the stratum corneum to the skin permeation of vitamin C. The DSC profile showed four very distinctive transitions near 100, 128, 135 and 145℃ which are associated with protein transitions. Comparing normal skin, the peaks are sharpened and there are additional phase transitions above 90℃. An increase in sharpness reflects an increase in the hydration state of the sample, as hydrogen bonds between H_2O molecules and other hydrogen donating chemicals of skin components become major chemical bonds in hydrated samples. The higher permeation rate of vitamin C observed may be due to its enhancing effect on the hydration capacity of skin and solubilizing action on the protein domain of the stratum corneum.