MEASUREMENT OF AEROSOLS IN ENGINEERED NANOMATERIALS FACTORIES FOR RISK ASSESSMENT

YUJI FUJITANI,TAKAHIRO KOBAYASHI 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2008 NANO Vol.3 No.4

In relation to potential health risks, there is little available information on exposure to aerosols containing nanometer-size particles in work environments in factories producing engineered nanomaterials. We measured the concentrations and size distributions of particles of nanometer-sized to coarse-sized particles in an engineered carbon nanomaterial factory and a titanium dioxide factory. In addition, particles were collected with a quartz fiber filter in the engineered carbon nanomaterial factory, and their morphology was examined by scanning electron microscopy and their carbon composition was examined with a carbon analyzer. In the carbon nanomaterial factory, the particle number increased to more than 105 cm-3 when a vacuum cleaner was used to clean the inside of the producing device, and the particle number increased for particles with a diameter of about 100 nm compared with the background. This is the only case an increase in particle numbers is observed during this measurement. The emitted particles appear to consist of agglomerates of carbon nanomaterial particles smaller than 100 nm. The major fraction was the EC3 fraction (EC: elemental carbon; combustion at 800°C in a 98:2 He/O2 atmosphere), which is a minor fraction in diesel engine particulate matter. This suggests that the combustion temperature can be used to differentiate atmospheric particulate matter from engineered carbon material. Personal sampling conducted in addition to stationary measurements in the titanium dioxide factory indicated that stationary measurements can be used to generate representative data on the basis of the particle number but not the particle mass.

Nanomaterials-assisted thermally induced neuromodulation

Congqi Yang,Seongjun Park 대한의용생체공학회 2021 Biomedical Engineering Letters (BMEL) Vol.11 No.3

Neuromodulation, as a fast-growing technique in neuroscience, has been a great tool in investigation of the neural pathwaysand treatments for various neurological disorders. However, the limitations such as constricted penetration depth, low temporalresolution and low spatial resolution hindered the development and clinical application of this technique. Nanotechnology,which refers to the technology that deals with dimension under 100 nm, has greatly infl uenced the direction of scientifi cresearches within recent years. With the recent advancements in nanotechnology, much attention is being given at applyingnanomaterials to address the limitations of the current available techniques in the fi eld of biomedical science includingneuromodulation. This mini-review aims to introduce the current state-of-the-art stimuli-responsive nanomaterials used forassisting thermally induced neuromodulation.

Plant Nanobionics: Engineering plants using Nanotechnology

곽선영 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.1

My talk will introduce a new research area ‘Plant Nanobionics’ to create the interface between living plants or plant organelles and functional nanomaterials. We found that nanoparticles have a unique ability to cross the plant cell membrane and even the double lipid bilayers of chloroplasts. This work led us to develop a mathematical model capable of guiding the rational design of nanoparticles for targeted delivery into specific compartments without the use of chemical or mechanical aid, which was well correlated with experimental results. By introducing rationally designed functional nanomaterials, we engineered wild-type plants to serve as self-powered photonic devices or environmental sensors. These research efforts showed that Plant nanobionics can be a starting platform of new technology using plants existed abundantly in nature.

An Insight of Nanomaterials in Tissue Engineering from Fabrication to Applications

Sharma Ritika,Kumar Sanjeev,Bhawna,Gupta Akanksha,Dheer Neelu,Jain Pallavi,Singh Prashant,Kumar Vinod 한국조직공학과 재생의학회 2022 조직공학과 재생의학 Vol.19 No.5

Tissue engineering is a research domain that deals with the growth of various kinds of tissues with the help of synthetic composites. With the culmination of nanotechnology and bioengineering, tissue engineering has emerged as an exciting domain. Recent literature describes its various applications in biomedical and biological sciences, such as facilitating the growth of tissue and organs, gene delivery, biosensor-based detection, etc. It deals with the development of biomimetics to repair, restore, maintain and amplify or strengthen several biological functions at the level of tissue and organs. Herein, the synthesis of nanocomposites based on polymers, along with their classification as conductive hydrogels and bioscaffolds, is comprehensively discussed. Furthermore, their implementation in numerous tissue engineering and regenerative medicine applications is also described. The limitations of tissue engineering are also discussed here. The present review highlights and summarizes the latest progress in the tissue engineering domain directed at functionalized nanomaterials.

A Comprehensive Review on Potential Application of Nanomaterials in the Field of Agricultural Engineering

Chowdhury Manojit,Kushwah Ajay,Satpute Ajay N.,Singh Sanjay Kumar,Patil Amit Kumar 한국농업기계학회 2023 바이오시스템공학 Vol.48 No.4

Purpose The purpose of this study is to explore the utilization of nanomaterials in the agricultural engineering sector and to understand their potential to contribute to sustainable growth in agriculture. Methods This comprehensive review paper synthesizes existing research and examines the integration of nanomaterials in various aspects of agricultural engineering. It delves into how nanomaterials can enhance the efficiency and performance of agricultural machinery, prime movers, tire technology, lubrication systems, coolant formulations, irrigation methods, plant protection strategies, fertilizer application mechanisms, and food processing techniques. The study also considers potential health and safety risks associated with nanotechnology in agriculture. Results The results of this review paper highlight the extensive potential of nanomaterials in revolutionizing agricultural practices. Nanotechnology has the capacity to significantly improve agricultural processes, making them more efficient and sustainable. The integration of nanomaterials in various agricultural components and processes has shown promising outcomes. However, it also underscores the need for ongoing research to address potential health and safety risks. Conclusion Incorporation of nanomaterials in agriculture holds great promise for sustainable growth and efficiency. It offers innovative solutions to enhance various aspects of agricultural engineering. While nanomaterials have the potential to revolutionize agriculture, it is crucial to proceed with caution and conduct continued research to mitigate potential health and safety risks. As agriculture seeks more efficient and sustainable practices, the integration of nanomaterials remains a frontier that necessitates ongoing exploration and vigilance in its implementation.

“Nanospace Engineering” by the Growth of Zinc-Based Nano Coordination Polymer Particle on Dendritic Fibrous Nanosilica (DFNS) and DFNS/Gold Hybrid Nanomaterials

( Tranminhngoc ),유효종 한국공업화학회 2020 한국공업화학회 연구논문 초록집 Vol.2020 No.-

Hybrid nanomaterials with unique tailored morphologies and compositions have been used for the targetoriented catalysts owing to the synergistic properties of the individual components. The rational development of nanohybrids are expected to enable unique nanospace engineering in the resulting systems. We report the fabrication of nanohybrids composed of dendritic fibrous nanosilica (DFNS) and DFNS/gold (DFNS/Au) hybrids as the core and zinc-based nano coordination polymer particle (so called nano metal-organic framework) (Zn-NMOF) as the shell (DFNS@Zn-NMOF). The combined fibrous morphology of DFNS and micropores of NMOF can be directly employed for nanospace engineering in the hierarchical systems in a controllable manner.

Adsorptive remediation of cobalt oxide nanoparticles by magnetized α-cellulose fibers from waste paper biomass

Kadam, Avinash,Saratale, Rijuta Ganesh,Shinde, Surendra,Yang, Jiwook,Hwang, Kyojung,Mistry, Bhupendra,Saratale, Ganesh Dattatraya,Lone, Saifullah,Kim, Dae-Youg,Sung, Jung-Suk,Ghodake, Gajanan Elsevier 2019 Bioresource technology Vol.273 No.-

<P><B>Abstract</B></P> <P>Remediation of engineered-nanomaterials is an up-coming major environmental concern. This study demonstrates adsorptive-remediation of cobalt oxide nanoparticles (CoO NPs) from the water. The α-cellulose-fibers were extracted from waste-paper biomass (WP-αCFs) and magnetized with Fe<SUB>3</SUB>O<SUB>4</SUB> NPs (M-WP-αCFs). The XRD, FT-IR, and TGA were performed for detailed characterization of the newly developed bioadsorbent. The M-WP-αCFs was then applied for adsorptive remediation of CoO NPs. The adsorptive kinetics of CoO NPs adsorption onto the M-WP-αCFs reveals the pseudo-second-order model. The various adsorption isotherm studies revealed Langmuir is a best-fit isotherm. A prominently high adsorption capacity <I>q<SUB>m</SUB> </I> (1567 mg/g) corroborated extraordinary adsorptive potential of M-WP-αCFs. Furthermore, CoO NPs were adsorbed onto M-WP-αCFs were analyzed by the XPS, VSM, and TEM. Therefore, this study gave rise WP biomass extracted and rapidly-separable nano-biocomposite of ‘M-WP-αCFs’ with a high-capacity for CoO NPs remediation and can be further applied in remediation of several other engineered-nanomaterials.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Office paper waste (WP) extracted α-cellulose fibers (αCFs) was magnetized. </LI> <LI> M-WP-αCFs presented an effective adsorptive-remediation of CoO NPs from the water. </LI> <LI> The adsorption kinetics followed a pseudo-second-order rate model. </LI> <LI> Langmuir adsorption isotherm model was best fit to the experimental data. </LI> <LI> M-WP-αCFs can be effective for remediation of engineered NPs from the water. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Current trends and challenges in cancer management and therapy using designer nanomaterials

Hemant Kumar Daima,Vincent M. Rotello,Suresh Kumar Bhargava,S. P. Srinivas,Anubhav Kaphle,P. N. Navya 나노기술연구협의회 2019 Nano Convergence Vol.6 No.23

Nanotechnology has the potential to circumvent several drawbacks of conventional therapeutic formulations. In fact, significant strides have been made towards the application of engineered nanomaterials for the treatment of cancer with high specificity, sensitivity and efficacy. Tailor-made nanomaterials functionalized with specific ligands can target cancer cells in a predictable manner and deliver encapsulated payloads effectively. Moreover, nanomaterials can also be designed for increased drug loading, improved half-life in the body, controlled release, and selective distribution by modifying their composition, size, morphology, and surface chemistry. To date, polymeric nanomaterials, metallic nanoparticles, carbon-based materials, liposomes, and dendrimers have been developed as smart drug delivery systems for cancer treatment, demonstrating enhanced pharmacokinetic and pharmacodynamic profiles over conventional

Carbon Nanotubes Based Engineering Toolkits: Review and Impact on Agricultural and Biological Technology Applications

( Hye-been Kim ),( Ki-taek Lim ) 한국농업기계학회 2016 한국농업기계학회 학술발표논문집 Vol.21 No.2

Engineered carbon-derived nanomaterials such as carbon nanotubes, graphene, and graphene oxide have been employed in the detection of analytes with electron transfer kinetics, which are most widely used in the electrochemical platform. Thus, this paper as feature article gives special attention to the solid design and use of carbon nanomaterials, most importantly single-walled carbon nanotubes (SWCNTs), multi-walled carbon nanotubes (MWCNTs), graphene oxide (GO), reduced graphene oxide (rGO), as platform-based biomaterials for agricultural and biological technology applications. Interestingly, carbon based-nanomaterials have some pros pertaining to a high surface-to-volume ratio, excellent electrocatalytic activity, robust biocompatibility and mechanical strength. This review paper highlighted some recent development on electrochemical platforms over SWCNTs, MWCNTs, GO, rGO, and nanocomposites as a promising biomaterial for agricultural and biological technology fields. The design and their platforms as an engineering toolkits of carbon based nanomaterials were described to demonstrate the key point of diagnostics and treatments throughout agricultural and biological technology.

Osteogenic differentiation of human mesenchymal stem cells in 3D printed carbon nanotube composites

Yu-Ri Seo,Dinesh Kumar Patel,Ki-Taek Lim 강원대학교 산림과학연구소 2018 강원대학교 산림과학연구소 학술대회 Vol.2018 No.09

In the emerging tissue engineering applications, porous scaffolds are used to support bone tissue cells to replace and complement the current approach of organ transplantation. The cornerstone of successful tissue engineering applications depends on two essential elements of cells and scaffolds, and the suitable design of a platform for three-dimensional (3D) scaffolding is determining both biomaterials and manufacturing protocols via detailed and exact mechanical and biological needs like biocompatibility, porosity, biodegradability, surface characteristics, and so forth. Recent carbon-nanomaterials have emerged as promising candidates for producing scaffolds that can replace tissues more efficiently. Importantly, carbon-nanomaterials (CNMs) offer interesting properties for biological applications due to their very high aspect ratio, combined with outstanding mechanical and electrical properties. In addition, the advantages of carbon nanomaterials on stem cells (such as efficient attachment, proliferation and differentiation) have been demonstrated in vivo and have provided initial consequence to support subsequent studies. In this work, a new three-dimensional (3D) printing system based on for fused deposition modeling (FDM) is developed for the fabrication of 3D nanocomposite-based microstructures. The results of our study suggest improved mechanical and biological properties of the 3D platform, and provide a high potential for application of nanomaterial scaffolds in a wide range of tissues.