최근 20년간 우리 나라 주요사인의 추이

김득조(Duk-Jo Kim),최봉근(Bong-Keun Choi),윤태영(Tai-Young Yoon),최중명(Joong-Myung Choi),박순영(Soon-Young Park),유동준(Dong-Joon Lew) 대한임상노인의학회 2000 대한임상노인의학회지 Vol.1 No.1

연구목적 : 최근에 이르러 우리 나라의 주요 사망원인은 전염성질환에서 비전염성의 만성퇴행성질환으로 현저히 변화되었다. 이제 저자들은 최근의 주요 사인의 변화양상과 그 추이를 검토하고저 본 연구를 수행하였다. 방법 : 그간 경제기획원, 통계정 및 기타 관련 정부 부서로부터 1977년이래 발표된 과거 20년간의 주요사인에 관한 통계자료를 수집, 연도별로 분석, 검토하여 최근 우리 나라에서 주요 사인의 변천양상과 그 추이를 고찰하였다. 결과 : 1970년대 후반 내지 1980년대 초반에서 주요사인이 전염성질환에서 비전염성의 만성퇴행성 질환으로 현저하게 역전되었는데, 특히 순환기계 질환과 악성 신생물이 수위권으로 괄목하게 부상하였다. 또한 1980년 중분이래 사망의 외인(불의의 사고)에 의한 사망이 점차 증가하여, 이제는 순환기계질환, 악성신생물(암) 그리고 사고(사망의 외인)은 三大주요사인이 되어 1996년도 현재 이 3대 사인이 전체사인의 약 61%를 차지하였다. 결론 : 주요사인의 추이를 보면, 과거에 위세를 떨치던 전염성질환(결핵포함)은 급격히 감소되었고, 비전염성의 만성퇴행성 질환인 소위 "성인병"인 순환기계질환과 암 그리고 만성폐쇄성 폐질환 등은 아직도 그 사망수준은 높은 실정이다. 또 각종 사고로 인한 사망률은 매년 꾸준히 증가하여 제 3위 사인으로 전체 사망의 약 15%를 차지하고 있다. Background : Recently the leading causes of death were remarkably changed from the communicable to the non-communicable chronic degenerative diseases. We tried to confirm the changing pattern and the transition of the recent leading causes of death in Korea. Methods : We have made an attempt to examine the changing pattern and the transition of the leading causes of death in our country recently since 1977 by analytically reviewing the annual statistical data on the causes of death for the latest two decades reported mainly from the Economic Planing Board, National Statistical Office and other informative materials. Results : After the inverting period of the late 1970s and 1980s changing remarkably from the communicable to the non-communicable disease, the leading causes of death were changed to the chronic degenerative diseases such as circulatory disease and malignant neoplasms recently. With the particularly increasing deaths due to the unintentional accidents since the mid-1980s, circulatory disease, malignant neoplasms and accidents became the three major causes of death, and accounted for about 61 percent of the total deaths in 1996. Conclusion : In reviewing the changing pattern, the transition of the leading causes of death, communicable diseases formidably prevailed for the past decades were rapidly decreased recently, and chronic degenerative disease, so-called, "Chronic Illness" such as circulatory diseases, malignant neoplasms, and chronic obstructive pulmonary disease are in tendency of continuous increase year by year.

만성질환 증상을 두 가지 이상 보유한 성인에 있어서 개인 단위의 영양교육 효과

윤진숙,정영혜,박정아,오현미 대한지역사회영양학회 2002 대한지역사회영양학회지 Vol.7 No.6

This study was intended to evaluate the overall effects of nutritional education on adults having two or more symptoms of chronic degenerative disease. A nine week nutritional education program was provided for 65 adults with chronic diseases. We assessed the changes in dietary knowledge, eating behavior and socio-psychological factors. When we evaluated the nutrient intakes of the subjects, their energy intake was 79.4% of the Korean Recommended Dietary Allowances (RDA). Their dietary intake of other nutrients was also below the RDA level except for Vitamin C. Their knowledge of dietary therapy was slightly improved after the implementing of nutritional education. The dietary behavior of ‘night snacks before sleep’was significantly improved. While the overall fear due to disease was significantly increased, self-efficacy was not improved. Self-efficacy for eating “three regular meals” and “choosing fruit, vegetable and grain” were significantly decreased. Family support for “buying food which is good for my health” was also significantly increased, whereas “advises me to eat appropriate foods for health” was decreased. Biochemical analysis indicated that blood levels of triglyceride, cholesterol and blood pressure improved after nutrition education. Therefore, we concluded that nutritional education program for people with chronic degenerative diseases could change the diet therapy knowledge, dietary behavior, and the fear due to disease, support from family and behavior intention toward the direction to improve the chronic disease condition. However, it did not improve self-efficacy. Our study also indicated that nutritional education strategies to improve self-efficacy should be an important aspect in a long term education plan for patients to establish desirable eating habits.

만성퇴행성 근골격질환 환자의 활동 제한에 따른 삶의 질

김현수(Hyun Su Kim) 다문화건강학회 2024 다문화건강학회지 Vol.14 No.1

Purpose: This is a descriptive research study to identify the change in the quality of life according to the restriction of activity in patients with chronic degenerative musculoskeletal disease. Methods: Based on the data of the 8th Korea National Health and Nutrition Examination Survey (KNHANES), the general and disease characteristics of the subjects were analyzed using frequency analysis, descriptive statistics, and quality of life according to restriction of activity were ana-lyzed by logistic regression on the SAS 9.4 program. Results: The results of the analysis showed that the quality of life in patients with chronic degenerative musculoskeletal disease was lower when there was activity restriction, which had a significant effect on mobility (B=1.437, OR 4.207[2.116, 8.364], <.001) and selfcare (B=1.541, OR 4.670[2.466, 8.843], <.001), and disrupted usual activities (B=1.691, OR 5.428[2.782-10.592], <.001). Pain/inconvenience (B=1.937, OR 6.943[3.776, 12.764], <.001) and anxiety/depression (B=.946, OR 2.576[1.380, 4.812], =.003) increased when there was activity restriction. Conclusion: Thus, activity limitations can have a major impact on the quality of life. Hence, efforts should be made to pay attention to the aspects of the health care system that can effectively prevent and manage os-teoarthritis and osteoporosis and reflect them politically.

근로자의 근무유형별 건강상태와 영양섭취상태 비교 연구

오현미,윤진숙 대한지역사회영양학회 2000 대한지역사회영양학회지 Vol.5 No.1

The study was curried out to collect information to establish a framework for nutrition education for the prevention of chronic degenerative disease. We analyzed differences in diet quality, food habits and health status of workers by work condition. Anthrometric parameters of height, weight and body fat were measured and biochemical parameters including glucose, total cholesterol, GOT, GPT and hemoglobin were determinded for 194 subjects. To assess the nutrient intake and diet quality of workers, dietary intake was measured by the day 24-hour recall method, Average daily nutrient intake, except for phos-phorous and vitamin C was lower than Korean RDA. The obesity related behavior score was significantly better in laborers than in office workers, while chronic degenerative diseases related to food habit score was significantly better in laborers than in office workers, while chronic degenerative diseases related to the food habit score was beet in offices workers than in laborers. Blood pressure, blood glucose levels were significantly higher in laborer than in office workers. Dietary variety score (DVS) food composition group score(FCGS), mean adequacy ratio(MAR) of office worker were better than those of labor workers. When diet quality was evaluated by FCGS(food composition group score) 16.0% of the subjects acquired 5 points and 14.4% of the subjects acquired 2 points. MAR and INQ showed a significantly positive correlation with DVS and FCGS . This results indicated that the onset possibility of hypertension and diabetes mellitus among chronic degenerative disease was higher in laborers than in office workers, while the onset possibility of obesity was higher in office workers than in laborers. In conclusion the overall diet quality of office workers is betters than that of laborers, therefore, nutrition education for prevention of chronic degenerative disease of industrial workers needs to be more focused on the improvement of the health status of laborers.

만성퇴행성 질환에 미치는 다시마(Laminaria japonica)와 후코이단 성분의 영향

최진호,김대익,박수현,김동우,이종수,유종현,정유섭 한국생명과학회 1999 생명과학회지 Vol.9 No.4

This study was designed to investigate the effects of sea tangle (Laminaria japonica) extract and fucoidan components on chronic degenerative diseases. Sprague-Dawley(SD) male rats (210$\pm$5g) were fed experimental diets: Dasi-Ex group: dasima extract powder of 4.0% added to control diet; Fuco-I, II and III groups: fucoidan powder of 1, 2 and 3% added to Dasi-Ex group for 45 days. Triglyceride (TG) levels in serum were significantly lower (10~15%) in Fuco-I, II and III groups compared with control group. Total cholesterol levels were significantly decreased (7~10% and 15~ 35%) in brain mitochondria and microsomes of Fuco-II and III group compared with control group. LDL-cholesterol levels were remarkably decreased (20~30%) in Dasi-Ex and Fuco-I, II, III groups, but HDL-cholesterol levels were significantly increased (10~12%) in Fuco-II and III groups only compared with control group. The ratios of HDL/total cholesterol resulted in a marked increase (3 5~55%) in Dasi-Ex and Fuco-I, II, III groups, but atherogenic indices were remakably decreased (40~50%) in Dasi-Ex and Fuco-I, II, III groups compared with control group. Membrane fluidities were remarkably increased (45~70% and 38~42%, respectively) in brain mitochondria and microsomes of Fuco-II and III groups compared with control group. Administrations of fucoidan added to dasima effectively decreased TG, total and LDL-cholesterol, and atherogenic index, while also effectively increased HDL-cholesterol, HDL/total cholesterol ratio, and membrane fluidity, suggesting chronic degenerative diseases were very effectively prevented by the administration of fucoidan component.

만성 신장질환으로 혈액 투석을 시행하는 환자의 퇴행성 요추 질환에 대한 수술 결과

장해동,이재철,신병준,홍시전,안중현,최성우,강덕원,조형규 대한척추외과학회 2017 대한척추외과학회지 Vol.24 No.3

Study Design: Retrospective study. Objectives: To analyze the outcomes of degenerative lumbar spine surgery in patients undergoing hemodialysis due to chronic kidney disease (CKD). Summary of Literature Review: Patients who undergo hemodialysis due to chronic renal disease tend to exhibit accelerated changes in bone quality, deterioration of spinal stenosis, and accompanying neurological degeneration. The surgical treatment of chronic spinal diseases is also becoming more necessary with the increased lifespan of these patients. Materials and Methods: We reviewed the medical records and radiographs of patients with CKD undergoing hemodialysis who were followed-up for more than 1 year after posterior lumbar spinal surgery. We evaluated clinical, laboratory, and radiologic variables. For a comparative analysis, patients were classified into subgroups according to age (65 years old), duration of hemodialysis (10 years), and type of surgery (simple decompression or fusion). Results: We included 21 patients (5 men, 16 women) with a mean age of 66.2 years (range, 48-87 years). The mean duration of hemodialysis and follow-up was 18.9 years and 43 months, respectively. Decompressions with fusion were performed in 11 patients and simple decompressions in the other 10. The mean visual analog scale (VAS) of leg pain and the Oswestry Disability Index (ODI) significantly improved after surgery at time of the last follow-up; meanwhile, the mean VAS score for lower back pain did not show a statistically significant improvement. The postoperative ODI was correlated with age (correlation coefficient=0.71, p=0.006). In patients less than 65 years old, the ODI improvement was greater (p=0.035) than in those 65 years of age or older. There was no significant difference in the clinical outcomes according to the duration of hemodialysis. Complications were observed in 11 patients (52.4%, 7 in fusion and 4 in simple decompression), of which 2 cases were infections, and reoperations were performed in 5 patients. The union rate of the fusion cases at the 1-year follow-up was 81.8%. Conclusions: Appropriate spine surgery improved radicular pain and the ODI in patients with degenerative lumbar disease undergoing hemodialysis. However, postoperative complications were frequent and the improvement of clinical outcomes was minimal, especially in patients over 65 years of age and in those who underwent fusion. Therefore, the surgical treatment of patients with chronic renal disease undergoing hemodialysis requires adequate consideration of age and the duration of hemodialysis. 연구 계획: 후향적 연구목적: 투석을 시행 중인 만성 신장질환 환자의 퇴행성 요추 질환에 대한 수술적 치료 후 임상적, 영상의학적 결과를 분석하고자 하였다. 선행 연구문헌의 요약: 만성 신장질환으로 인한 혈액투석을 시행하는 환자는 골질의 변화, 척추관 협착증의 악화, 그리고 동반하는 신경학적인 퇴행이 가속화되는 경향이 있다. 해당 환자군의 수명 증가와 함께 만성 척추 질환에 대한 수술적 치료의 필요성 또한 증가하고 있다. 대상 및 방법: 만성 신장질환으로 혈액투석을 시행하는 환자 중 퇴행성 요추 질환으로 본원에서 후방 접근에 의한 척추 수술 시행 받고 1년 이상 추시된환자를 대상으로 하여, 의무 기록과 영상 검사를 검토하였다. 임상지표와 영상의학적 자료 등을 조사하였으며, 나이(65세 이상과 미만의 군), 혈액투석 기간(10년 이상과 미만의 군), 수술의 종류(단순 감압술, 유합술)에 따른 결과를 비교 분석하였다. 결과: 대상 환자는 총 21명(남자 5명, 여자 16명)이었고, 평균 나이는 66.2(48~87)세였다. 평균 투석기간은 18.9년이었고, 추시 기간은 43개월이었다. 유합술이 11예, 단순 감압술이 10예였다. 하지 방사통의 평균 VAS 점수와 평균 ODI 점수는 술전에 비해 최종 추시시 유의하게 호전되었으나 요통의 평균VAS 점수는 통계적으로 유의한 호전을 보이지 않았다. 술 후 최종 ODI는 환자의 나이증가와 유의한 상관관계를 보였고(상관계수=0.71, p=0.006), 65세미만의 환자 군에서 술 후 ODI의 호전 정도가 유의하게 컸다(p=0.035). 혈액투석 기간에 따른 임상결과는 유의한 차이가 없었다. 수술 후 합병증은 총 11 명(유합술 7예, 감압술 4예)에서 관찰되었고, 그 중 감염은 2예였으며, 재수술은 5명 환자에서 시행되었다. 유합술 환자의 술 후 1년째 유합율은 81.8%였다. 결론: 혈액투석을 시행중인 만성 신장질환 환자에서 적절한 척추 수술 시행 후 하지 방사통과 ODI점수는 유의하게 호전되었으나, 합병증이 발생하는 경우가 빈번하고, 특히 65세 이상과 유합술 환자군에서 임상 결과의 호전이 미미하였다. 따라서 혈액투석 중인 만성 신장질환 환자의 수술적 치료는 나이및 투석 기간 등에 대한 충분한 고려가 필요할 것으로 사료된다. 약칭 제목: 혈액투석환자 퇴행성요추 수술결과

사무직과 생산직 근로자의 영양실태 비교 및 건강 관련 요인 분석

김순경,연보영,장정희 대한영양사협회 2003 대한영양사협회 학술지 Vol.9 No.4

This study was carried out to collect information to establish a framework for meal management and nutritional service for prevention of chronic degenerative disease in the industrial workers. We investigated the health concerned life-style, nutrient intakes, anthropometry and biochemical parameters in the male workers in Korea by work condition. Anthropometric parameters of height, weight. waist, hip and triceps skinfold thickness were measured and bioched parameters including Urine pH. hemoglobin. blood glucose, total cholesterol GOT, GPT, 7-GPT and blood pressure were determind for 101 subjects(50 office workers : 33.9 yr, 51 laborers : 34.4 yr). To assess the nutrient intakes and diet quality of workers dietary intake was measured by one day 24-hour recall method. Result of anthropmetric parameters of height(P<0.01). weight(P<0.05). hp(P<0.05), TSF(P<0.01) were significantly higher in office workers than in laborers. Biochemical parameters were not significantly difference in both of them. Average daily nutrient intakes of both group was higher than the Korean RDA and report on 2001 National Health & Nutrition Survey. The calcim(P<0.0l), iron(P<0.05). vitamin A(P<0.01). vitamin B₁(P<0.01) and niacin(P<0.05) intakes in laborers were significantly higher than in office workers. Nutrition adequacy ratio(NAR), mean adequacy ratio(MAR) and index of nutritional quality(INQ) of laborers were higher than those of office workers. This results indicated that the onset possibility of chronic degenerative disease appeared higher in office workers. Therefore, meal menagement and nutritional service for prevention of chronic degenerative disease of industrial works needs to be more variant guidelines.

기억. 학습장애 동물모델 SAMP8에 미치는 알로에(Aloe vera)의 영향 II. SAMP8의 지질대사에 미치는 알로에의 투여효과

최진호,김동우,유제권,한상섭,심창섭,Choi, Jin-Ho,Kim, Dong-Woo,Yoo, Je-Kwon,Han, Sang-Sub,Shim, Chang-Sub 한국생명과학회 1996 생명과학회지 Vol.6 No.3

Aloe(Aloe vera LINNE) has been used as a home medicine for the past several thousand in the world, and has been studied on various chronic degenerative diseases such as atherosclerosis, myocardiac infarction and hypertension. SMAP8, learning and memory impairment animal mode, were fed basic or experimental diets with 1.0% of freeze dried(FD)-Aloe powder for 8 months. This study was designed to investigate the effects of Aloe on body weight gain, grading score of senescence(GSS), triglyceride, total and LDL-cholesterol levels, and atherogenic index in serum of SAMP8, and also designed to investigate the effects of Aloe on cholesterol accumultions in mitochondria and microsome fractions of SAMP8 brain. Body weight gain was consistently lower in aloe group than in control group, but no significantly differences between them. Grading score of senescence resulted ina marked decreases pf 20% in 1.0% Aloe group compared with control group. Administrations of 1.0% aloe resulted ina marked decreases in 15% and 20% of triglyceride and cholesterol levels, respectively, and also significantly decreased in 15% of LDL-cholesterol levels and atherogenic index in serum of SAMP8 compared with control group. Cholesterol accumulations were significantly inhibited in 20% and 10% of mitochondria and microsome fractions of SAMP8 brain, respectively, by administration of 1.0% Aloe. These results suggest that administration of Aloe mau not only effectively inhibit chronic degenerative diseases in serum of SAMP8, but may also improve learning and memory impairments of SAMP8 brain.

운동프로그램이 여성 노인의 요부체위에 미치는 영향

권봉안 한국스포츠학회 2011 한국스포츠학회지 Vol.9 No.2

Evaluation of chronic cerebral hypoperfusion model in mouse

Eun-Joo Lee,Jaejoon Choi,Hwachul Shin,Eun Hyung Lee,A-Ram Yoo,Doyeong Pyeon,Jung-Hu Shin,Jee-Hyun Choi,Jae Jun Lee,Daeyu Kim,Ki Wook Moon,Ha-Young Jang,WooSung Choi 한국실험동물학회 2018 한국실험동물학회 학술발표대회 논문집 Vol.2018 No.7