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        Comparison of Constituents, Antioxidant Potency, and Acetylcholinesterase Inhibition in Lentinus edodes, Sparassis crispa, and Mycoleptodonoides aitchisonii

        이미라,Jing Gang Hou,Shahnaz Begum,Jian Jie Xue,Yun Bo Wang,성창근 한국식품과학회 2013 Food Science and Biotechnology Vol.22 No.6

        This study evaluates three edible mushrooms:Lentinus edodes, Sparassis crispa, and Mycoleptodonoidesaitchisonii, in terms of acetylcholinesterase (AChE)inhibition, antioxidant potency and constituents free aminoacids and mineral. The concentration of essential aminoacids was found to be 34.10 mg/g in M. aitchisonii, 26.25mg/g in S. crispa, 25.99 mg/g in L. edodes. S. crispadisplayed the highest DPPH scavenging activity andphenolic contents. The best results for AChE inhibitionwere obtained from M. aitchisonii. These results suggestthat M. aitchisonii has high potential for cognitiveimprovement by AChE inhibition and antioxidant potency.

      • KCI등재후보

        Antioxidant Efficacy of Nasturtium officinale Extracts Using Various In Vitro Assay Systems

        Seifollah Bahramikia,Razieh Yazdanparast 사단법인약침학회 2010 Journal of Acupuncture & Meridian Studies Vol.3 No.4

        Nasturtium officinale R. Br. (watercress), of the family Brassicaceae, has been long used as a home remedy or a medicinal plant by the people of southeastern Iran. The aim of this study was to investigate the antioxidant activity of N. officinale extract using various in vitro assay systems, including the ferric reducing antioxidant power and 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonate) assays, 1,1-diphenyl-2-picrylhydrazyl, hydrogen peroxide, nitric oxide radical scavenging, and ferrous ion chelating activity, as well as the inhibitory effect on ferrous ion/ascorbate induced lipid peroxidation, in rat liver homogenate. The results revealed that N. officinale extract possesses potent reducing power in a ferric reducing antioxidant power assay, concentration-dependent scavenging ability on 2,2-azinobis 3-ethylbenzothiazoline-6-sulfonate, 1,1-diphenyl-2-picrylhydrazyl, nitric oxide radicals,and hydrogen peroxide, as well as chelating ability on ferrous ions. Furthermore,N. officinale extract prevented thiobarbituric acid reactive substances formation in ferrous ion/ascorbate induced lipid peroxidation in rat liver homogenate in a dosedependent manner. In addition, this N. officinale extract had the phenolic and flavonoid contents of 96.2 mg gallic acid equivalents/g dried extract and 63.2 mg catechin equivalents/g dried extract, respectively. The cumulative results clearly indicate that N. officinale extract possesses potent antioxidant properties probably mediated through direct trapping of free radicals, reducing power, and also through metal chelating. Based on its antioxidative potential, N. officinale extract might find applications in the prevention of free radical-related diseases.

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