http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 주제어 : Zn-aminoclays (검색결과 1 건)
- 무료
- 기관 내 무료
- 유료
-
Chun, H.S.,Park, D.,Eun Lim, S.,Jeong, K.H.,Park, J.S.,Park, H.J.,Kang, S.,Kang, K.S.,Park, H.G.,An, H.R.,Huh, Y.S.,Lee, Y.C. Academic Press 2017 Ecotoxicology and environmental safety Vol.137 No.-
<P>Two zinc-aminoclays [ZnACs] with functionalized primary amines [(-CH2)(3)NH2] were prepared by a simple solgel reaction using cationic metal precursors of ZnCl2 and Zn(NO3)(2) with 3-aminopropyl triethoxysilane [APTES] under ambient conditions. Due to the facile interaction of heavy metals with primary amine sites and Zn-related intrinsic antimicrobial activity, toxicity assays of ZnACs nanoparticles (NPs) prior to their environmental and human-health applications are essential. However, such reports remain rare. Thus, in the present study, a cell viability assay of in-vitro HeLa cells comparing ZnCl2, Zn(NO3)(2) salts, and ZnO (similar to 50 mn average diameter) NPs was performed. Interestingly, compared with the ZnCl2, and Zn(NO3)(2) salts, and ZnO NPs (18.73/18.12/ 51.49 mu g/mL and 18.12/15.19/46.10 mu g/mL of IC50 values for 24 and 48 h), the two ZnACs NPs exhibited the highest toxicity (1050 values of 21.18/18.36 mu g/mL and 18.37/17.09 mu g/mL for 24 and 48 h, respectively), whose concentrations were calculated on Zn elemental composition. This might be due to the enhanced bioavailability and uptake into cells of ZnAC NPs themselves and their positively charged hydrophilicity by reactive oxygen species (ROS) generation, particularly as ZnACs exist in cationic NP's form, not in released Zn2+ ionic form (i.e., dissolved nanometal). However, in an in-vivo embryotoxicity assay in zebrafish, ZnACs and ZnO NPs showed toxic effects at 50-100 mu g/mL (corresponding to 37.88-75.76 of Zn wt% mu g/mL). The hatching rate (%) of zebrafish was lowest for the ZnO NPs, particularly where ZnAC-[(NO3)(2)] is slightly more toxic than ZnAC-[Cl-2]. These results are all very pertinent to the issue of ZnACs' potential applications in the environmental and biomedical fields.</P>
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
