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        Maternal selenium-supplementation at various stages of periconception period: influence on murine blastocyst morphology and implantation status

        Mamon, Mark Anthony C.,Ramos, Gliceria B. Korean Society of Animal Sciences and Technology 2017 한국축산학회지 Vol.59 No.4

        Background: Selenium is one of the trace minerals whose deficiency is known to lead to complications of female reproduction. The identified gaps in researches regarding selenium and pregnancy include optimizing the dosage of selenium supplementation, timing of supplementation, finding the best form and type of selenium, and selenium administration combined with other antioxidants. Hence, this study was conceptualized to address one of the identified gaps, that is, to find out the best timing of selenium administration around the time of pregnancy. Specifically, this study aimed to assess the effects of maternal Selenium-supplementation, administered at various stages of periconception period, on murine blastocyst morphology, percent occurrence of good quality blastocysts, and implantation status. Methods: ICR female mice were randomly assigned into the unsupplemented group (Group I) receiving basal diet without selenium, and treatment groups given with $3.0{\mu}g$ selenium-supplement per day during pregestation only (Group II), pregestation-throughout-gestation (Group III) and gestation only (Group IV). Both blastocyst morphology and implantation status were assessed. Results: The morphometric measurements of blastocysts appeared to be unaffected by selenium-supplementation at different stages of periconception. Selenium-supplementation at pregestation only (Group II) and gestation only (Group IV) produced higher percent occurrence of good quality blastocysts and lower percent pre-implantation loss than Group III. Among all the treatment groups, Group III (Selenium-supplementation during pregestation-to-gestation) yielded the lowest quality blastocysts and highest percent pre-implantation loss. Conclusion: Maternal selenium-supplementation during pregestation and gestation stages of the periconception period yielded a high percent occurrence of good quality blastocysts and pre-implantation success.

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        사전교육이 정상 청력자의 인공와우 이해에 미치는 영향

        허승덕 대한치료과학회 2020 대한치료과학회지 Vol.12 No.1

        Objective: A cochlear implant is a device into the inner ear, which is expensive for implantation and rehabilitation. Implantation using a device is very important for rehabilitation, and correct recognition of device is a key factor for successful implantation. For this, it is necessary to confirm the educational effectiveness for pre-service education. The aim of this study is to investigate the effect of pre-service education on the understanding of cochlear implants. Participants and Method: Twenty healthy adults without hearing loss(m: f=6: 14, mean 33.8 ± 14.43 years) participated. The questionnaire was conducted before and after education, and responses were measured on a 5-point scale. The questions consisted of 5 subcategories and 20 items, including device understanding, cosmetology, surgery and rehabilitation costs, social attention, and audiology, rehabilitation. Pre-service education was conducted individually for 30 to 40 minutes, including the concept and structure, candidacy, rehabilitation, and precautions. Results: The first and second scores were 2.94 and 4.43, 2.6 and 2.83, 2.26 and 3.85, 2.5 and 2.93, 3.34 and 4.3, in same order, respectively. Statistically, significant changes were observed in understanding, cost, and rehabilitation. Conclusion: Pre-service education can provide useful information in the categories of device understanding, cosmetology, cost, social attention and rehabilitation.

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