다발성 뇌신경마비를 보인 B세포 악성림프종

박진영 ( Jin Young Park ),이성은 ( Sung Eun Lee ),유지현 ( Ji Hyun Yu ),박종원 ( Chong Won Park ) 대한내과학회 2009 대한내과학회지 Vol.77 No.4

We report a case of B-cell lymphoma with multiple asymmetrical cranial nerve palsies as the initial presentation. A 70-year-old woman complained of chin numbness, diplopia, dysarthria, and headache that had developed insidiously over the previous 2 months. The neurological examination showed multiple cranial nerve dysfunction, including right V and left VI nerve palsies. Her cerebrospinal fluid was normal, while her bone marrow biopsy revealed CD20-positive B-cell lymphoma. Five days after starting R-CHOP (rituximab-cyclophosphamide, adriamycin, vincristine, prednisolone) chemotherapy, her cranial nerve palsies and pain had improved markedly. Twenty days after starting R-CHOP chemotherapy, however, she was rehospitalized due to general worsening paralysis. In the hospital, the general paralysis progressed rapidly and she lapsed into delirium. No additional treatment was given based on the directives of her guardian and herself, and she was allowed to leave the hospital for hospice care. (Korean J Med 77:522-526, 2009)

중두개와 접근법을 사용한 안면신경마비감압술

장철호,강금위,김종길 圓光大學校 醫科學硏究所 1996 圓光醫科學 Vol.12 No.2

The middle cranial fossa approach can be used to expose the internal acoustic canal and labybithine segments of the facial nerve when preserving existing auditory function is desirable. The geniculate ganglion and tympanic portions of the nerve can also be decompressed from a using this approach. However, this technique requires complete acknowldegement of the complex three-dimensional anatomy of the temporal hone and the skull base. Recently we performed this technique in the case of the temporal bone fracture with facial nerve paralysis. We got succesful result, so we report our experience with the review of the literature.

말초성 안면마비 환자의 한방치료 치험례

정유진,최아련,한동근,강아현,서혜진,성재연,송우섭,이형철,엄국현,김수연,Jung, You-jin,Choi, A-ryun,Han, Dong-kun,Kang, A-hyun,Seo, Hye-jin,Sung, Jae-yeon,Song, Woo-sub,Lee, Hyung-chul,Eom, Gook-hyun,Kim, Soo-yeon 대한한방내과학회 2017 大韓韓方內科學會誌 Vol.38 No.5

Objective: Facial nerve palsy is caused by damage to the 7th cranial nerve. It is the main symptom of facial muscle paralysis on the affected side. Usually, recovery from this disease begins 2-3 weeks after onset and most patients recover in 4-8 weeks. If the patients cannot receive proper treatment, severe permanent impairments, both physical and mental, may remain, so this disease should be treated appropriately. In this study, a patient with facial nerve palsy was admitted to the Korean medicine hospital for treatment. We report on the patient's progress and the effects of treatment. Methods: We cured the patient with herbal medicines, acupuncture, herbal acupuncture therapy, and physical therapy. We used a numerical rating scale, the House Brackmann grading system, and a weighted regional grading system to assess symptom changes. Result: The patient with facial nerve palsy was hospitalized for 23 days and recovered from symptoms without significant problems on the face or in motor function.

안면신경마비를 주소로 한 베게너육아종증

이윤종 ( Yun Jong Lee ),최영주 ( Young Joo Choe ),이은봉 ( Eun Bong Lee ),김현아 ( Hyun Ah Kim ),송영욱 ( Yeong Wook Song ) 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.3

Wegener`s granulomatosis is a serious multi-systemic disease pathologically characterized by necrotizing vasculitis and granuloma. Although nervous system is one of major target organs in Wegener`s granulomatosis, the involvement of facial nerve was rarely reported as an initial symptom. We experienced a female patient with Wegener`s granulomatosis presenting otitis media, sinusitis and right facial palsy. Nasal mucosal biopsy revealed necrotizing vasculitis with granuloma formation, which was consistent with Wegener`s granulomatosis. During steroid and cyclophosphamide therapy, she developed paralysis of abducens nerve. Methyprednisolone pulse therapy was administrated with symptomatic improvement. We describe a case of Wegener`s granulomatosis presenting facial nerve palsy.

두부외상환자의 신경안과적 분석

김훈민,김대현 대한안과학회 2019 대한안과학회지 Vol.60 No.11

Purpose: To investigate the types and clinical features of neurological diseases after head trauma. Methods: From March 2010 to December 2018, a total of 177 patients were enrolled in this study. We retrospectively reviewed the clinical features of neurological ophthalmic diagnoses and frequencies, the types of head injuries, and the prognoses. Results: Cranial nerve palsy was the most common (n = 63, 35.6%), followed by traumatic optic neuropathy (n = 45, 25.4%), followed by optic disc deficiency, ipsilateral visual field defect, Nystagmus, skewing, ocular muscle paralysis between nuclei, and Terson syndrome. Neuro-ophthalmic deficits occurred in relatively strong traumas accompanied by intracranial hemorrhage or skull fracture. However, convergence insufficiency and decompensated phoria occurred in relatively weak trauma such as concussion. The prognoses of the diseases were poor (p < 0.05) for traumatic optic neuropathies and visual field defects. The prognoses of neurological diseases were poor if accompanied by intracranial hemorrhages or skull fractures (p < 0.05). Conclusions: After head trauma, various neuro-ophthalmic diseases can occur. The prognosis may differ depending on the type of the disease, and the strength of the trauma may affect the prognosis. 목적: 두부외상 후에 나타나는 신경안과적 질환의 종류 및 임상양상에 대해 알아보고자 하였다. 대상과 방법: 2010년 3월부터 2018년 12월까지 두부외상 후 발생한 신경안과적 질환으로 경과 관찰을 시행했던 총 177명의 환자들을 대상으로 신경안과적 진단명 및 빈도, 두부손상의 형태, 질환별 예후 등의 임상양상을 후향적으로 조사하였다. 결과: 3, 4, 6번 뇌신경마비가 총 63명(35.6%)으로 가장 많았고, 외상시신경병증이 45명(25.4%)으로 그 뒤를 이었다. 그 밖에 눈모음부족증, 동측성시야결손, 대상부전사시, 안진 및 스큐편위, 핵사이 눈근육마비, 터손증후군 등이 발생하였다. 두개내출혈이나 두개골골절 등이 동반되는 비교적 강한 외상에서 신경안과적 질환이 잘 발생하였으나, 눈모음부족증, 대상부전사시 등은 뇌진탕과 같은 비교적 약한 외상에서도 발생하였다. 질환별 예후는 외상시신경병증 및 시야결손과 같은 원심성 질환이 좋지 않았다(p<0.05). 또한 두개내출혈이나 두개골골절 등이 동반되면 전체 신경안과 질환의 예후가 좋지 않았다(p<0.05). 결론: 두부외상 후에는 다양한 신경안과적 질환이 나타날 수 있다. 질환의 종류에 따라 예후가 다를 수 있으며 외상의 강도도 예후에 영향이 있을 것으로 생각된다.

外旋神經麻痺 斜視患者의 韓方治驗 1例

金中鎬,金倫範,蔡炳允 경희대학교 1994 慶熙醫學 Vol.10 No.3-4

外旋神經痲痺 斜視患者의 韓方治驗 1例

김중호,김윤범,채병윤,Kim, Joong-Ho,Kim, Yoon-Bum,Chae, Byung-Yoon 대한한방안이비인후피부과학회 1994 한방안이비인후피부과학회지 Vol.7 No.1

We report one case with paralysis of the sixth cranial nerve, which was diagnosed at Kyung Hee Unversity Hospital. The patient was happened with traffic accident. He showed disorder of both abduction eye movement, headache, double vision and dizziness. We have experienced good improvement to recover paralytic strabismus by the Oriental Medicine.

Improved Symptoms of Peripheral Facial Nerve Palsy in ChAdOx1 nCoV-19 Vaccine Recipients Following Complex Korean Medicine Treatment

장우석,장정은,Jung Chan-yung,김경호 대한침구의학회 2022 대한침구의학회지 Vol.39 No.2

Peripheral facial nerve palsy is a neurological condition/disease characterized by unilateral paralysis of the facial muscles. We report the effects of complex Korean medicine treatment in 2 patients diagnosed with Bell’s palsy who developed symptoms 3-4 days following vaccination with ChAdOx1 nCoV-19 and who received oral steroids and antiviral medications. Complex Korean medicine treatments including acupuncture, electroacupuncture, bee venom acupuncture, cupping therapy, herbal medicine, and physical therapy were performed. Symptom improvement was evaluated daily using the Numerical Rating Scale, House- Brackmann Grade, and Yanagihara’s Score. Patient 1 was hospitalized for 22 days and Patient 2 visited the outpatient clinic 20 times. In both cases, postauricular pain caused by Bell’s palsy disappeared, and symptoms of facial paralysis improved following completion of treatment. These findings could suggest that combined Korean medicine treatment may improve symptoms of peripheral facial nerve palsy.

Epstein-Barr Virus Related Multiple Cranial Nerve Neuropathy

오세준,문미진,공수근,고의경 대한이비인후과학회 부산,울산,경남 지부회 2017 임상이비인후과 Vol.28 No.2

We present multiple cranial nerve paralysis including 6th, 7th and 8th cranial nerve in a 52-year-old woman with acute Epstein-Barr Virus (EBV) infection. While polyneuropathy has already been reported to be a potential sequelae for Epstein Virus infection, the specific combination of CN 6-8 palsies has not been published although there have been reports of diplopia with other neuropathies in other reports. The information here would add much to the literature in managing several polyneuropathy.

다발성 뇌신경 마비로 진행된 두경부 MALT Lymphoma 1예

김대연,이창배,박민경,이동근 대한이비인후과학회 2019 대한이비인후과학회지 두경부외과학 Vol.62 No.12

Lymphoma is a malignant tumor arising from the lymphoid tissue. Chronic inflammation canmake lymphocyte accumulation and proliferation in the mucous membrane. Sustained accumulationof these persistent changes in the lymphoid tissues may be responsible for the developmentof mucosa-associated lymphoid tissue (MALT) lymphoma. Although multiple cranialnerve palsy have been reported in various lymphoma, it has never been reported in MALTlymphoma. A 39-year-old man reported of facial palsy and subsequent vocal fold palsy. MALT lymphoma was diagnosed as involving the parotid gland, nasopharynx, and the skullbase. Vocal palsy and facial palsy were successfully recovered after chemotherapy.