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고령자의 수분 모니터링을 위한 체내 수분 정도 판단 알고리즘 검증
정지수(J. S. Jeong),김경(K. Kim),유미(M. Yu),홍철운(C. U. Hong),권대규(T. K. Kwon) 한국재활복지공학회 2020 재활복지공학회논문지 Vol.14 No.3
본 연구는 고령자를 위한 피드백을 제공하는 포괄적인 개념의 수분 모니터링을 위한 기초 기술을 개발하고자 하였다. 이를 위해 유도된 인위적 탈수 및 회복 과정에 대한 인체영향평가를 통하여 개발의 유효성을 검증하고자 하였다. 피험자는 청장년층 10명 및 고령자층 5명으로 구성되었다. 피험자는 고체 음식 및 첨가물이 함유된 음료의 섭취를 자제하였다. 실험 초기에는 기준값으로써 심박수 및 GSR(Galvanic Skin Response), 체온, 총 체수분율, 수분 손실률을 10분간 측정하였다. 이후, 10분간의 계단 운동을 통한 인위적 탈수를 진행하였다. 인위적 탈수 직후, 동일한 측정 요소(심박수, GSR, 체온, 총체수분율, 수분 손실률)을 15분간 측정하였다. 인위적 탈수 단계 이후, 피험자는 600mL의 생수를 섭취하는 회복 단계를 진행하였다. 생수 섭취 직후, 피험자는 앞서 측정한 요소를 15 분간 측정하였다. 평가 결과, 인위적 탈수로 인하여 심박수 및 GSR, 체온, 총체수분율이 증가하였으며, 수분 손실률이 감소하였다. 이후 수분 섭취를 통한 회복 과정에서 심박수 및 GSR, 체온, 총체수분율은 감소하였고, 수분 손실률은 증가하였다. 또한, 고령자층의 경우, 청장년층에 비하여 외부 요인으로 인한 변동성이 적은 경향을 보였다. This study was intended to develop a basis technology for hydration monitoring with a comprehensive concept of providing feedback for the elderly. To this end, we tried to verify the effectiveness of the development by evaluating the human impact on the induced artificial dehydration and recovery process. Subjects consist of 10 young adults and 5 elderly people. Subjects refrained from eating solid foods and beverages containing additives. At the beginning of the experiment, heart rate, GSR (Galvanic Skin Response), body temperature, total body water("TBW" or "%TBW") and fluid loss were measured for 10 minutes as baseline value. Thereafter, artificial dehydration was performed through a 10-minute stair movement. Immediately after artificial dehydration, the same measurement factors (heart rate, GSR, body temperature, total body hydration content and hydration loss rate) were measured for 15 minutes. After the artificial dehydration step, the subject proceeded with a recovery step of intaking 600 mL of mineral water. Immediately after intake of bottled water, the subject measured the previously measured factor for 15 minutes. As a result of the evaluation, the heart rate, GSR, body temperature and total body water were increased and fluid loss rate was decreased due to artificial dehydration. Then, in the recovery process through water intake, heart rate, GSR, body temperature, and total body water content decreased, and the water loss rate increased. In addition, the elderly group tended to have less variability due to external factors compared to the younger adult group.
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인간포배기 배아의 효과적인 유리화 동결법의 개발을 위한 연구
이상민,이주희,이상원,이승민,윤산현,임진호,박흠대,이성구,Lee, Sang-Min,Lee, Ju-Hee,Lee, Sang-Won,Lee, Seoung-Min,Yoon, San-Hyun,Lim, Jin-Ho,Park, Huem-Dai,Lee, Seong-Goo 대한생식의학회 2003 Clinical and Experimental Reproductive Medicine Vol.30 No.3
Objective: The purpose of this study was to evaluate the survival rate of vitrified blastocyst according to the freezing vessels, equilibration time in cryoprotectant and artificial dehydration method. Methods: Human blastocysts were vitrified after loading onto the plastic straw, open-pulled straw (OPS), electron microscopy grid (EM grid) for 1.5 min or 3 min. They also were directly plunged into LN2 within 30sec. For artificial shrinkage of blastocysts, 36 gauge fine needle was pushed at the cellular junction of the trophectoderm into the blstocoele cavity until it shrank without damage of inner cell mass. Results: The survival rate of vitrified blastocysts on plastic straw, OPS, EM grid as freezing vessels were 26.7, 13.0 and 60.5%, respectively. The survival rate of EM grid was significantly higher than that of plastic straw and OPS (p<0.05). For 1.5 min equilibrium, the survival rates of early blastocyst (EB), middle blastocyst (MB) and late blastocyst (LB) were 64.4, 81.0, and 20.0% respectively. For 3 min equilibrium, the survival rates of EB, MB, and LB were 69.9, 50.0 and 57.5% respectively. The survival rates of EB and MB were significantly higher than that of LB in 1.5 min equilibrium group (p<0.05), however, the significance was not observed in 3 min equilibrium groups. In cytoplasmic shrinkage before vitrification, the survival rates of EB, MB and LB were 92.9, 100 and 75.9% respectively. The survival rate of MB was significantly higher than that of LB (p<0.05). The survival rates of vitrified blastocysts by artificial dehydration and slow-frozen blastocysts were not significantly different as 88.9 and 66.7%, respectively. Conclusion: This study showed that the vitrification of human blastocysts using EM grid and artificial dehydration is an effective method. Therefore, these methods would be an useful techniques for blastocyst cryopreservation.
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S. Alamolhoda,M. Kazemeini,A. Zaherian,M.R. Zakerinasab 한국공업화학회 2012 Journal of Industrial and Engineering Chemistry Vol.18 No.6
In this research nano g-Al2O3 catalyst was synthesized through precipitation process then characterized and utilized for methanol dehydration reaction in a slurry batch reactor in route to the indirect synthesis of the dimethyl ether (DME). In this venue, effects of the key parameters on methanol conversion and catalyst stability were investigated. Moreover, the internal and external mass transfer resistances were eliminated; hence the intrinsic kinetics controlled the reaction. Therefore, the optimum conditions for temperature, methanol concentration, catalyst mass and stirrer speed were determined to be 300 8C,1.18 mol/l, 1.5 g and 1100 rpm, respectively. Next, different reaction rate equations from literature were applied to the measured experimental data where their generality compared to a new reaction rate equation examined. Ultimately, artificial neural networks applied to determine a model for the reaction rate estimation. It has been shown that the proposed reaction rate equation might be used rather satisfactorily to provide a base model for the neural networks; consequently a very good proximity to the reaction dynamics resulted.
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