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김아련,구해주,Md. Anisuzzaman Chowdhury,장영수,우은란 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.6
Ten compounds, 10,30-propanediol,20-amino-10-(1,3-benzodioxol-5-yl) (1), artanomaloide (2), canin (3),eupatilin (4), quercetin-3-O-b-D-glucoside-7-O-a-L-rhamnoside(5), 1,3-di-O-caffeoylquinic acid (6), isoquercitrin(7), pinoresinol-4-O-b-D-glucoside (8), scopolin (9), andisofraxidin-7-O-b-D-glucopyranoside (10) were isolatedfrom the aerial parts of A. selengensis. The structures ofcompounds (1–10) were identified based on 1D and 2DNMR, including 1H–1H COSY, HSQC, HMBC and NOESYspectroscopic analyses. Among them, compound 1was isolated from this plant for the first time as a naturallyoccurring compound. The inhibitory activity of these isolatedcompounds against interleukin-6 (IL-6) production inTNF-a stimulated MG-63 cells was also examined.
Koo, Kyoung-Ah,Kwak, Jong-Hwan,Lee, Kang-Ro,Zee, Ok-Pyo,Woo, Eun-Rhan,Park, Ho-Kun,Youn, Hyun-Joo The Pharmaceutical Society of Korea 1994 Archives of Pharmacal Research Vol.17 No.5
Effects of the polysaccharide fractions purified from Artemisia selengensis and Artemisia iwayomogi on the immune system was studied. The polysaccharide fractions, respectively called ASP1 and AIP1, may interact with macrophages and lymphocytes in spleen, increasing the population of those cell types in vivo and in vitro. Both ASP1 and AIP1 fractions also syuppress transplanted tumor cell growth and augment antibody production. This study suggests that ASP1 and AIP1 fractios may have immunomodulating and antitumor activities.
물쑥의 성분 및 이들 성분이 흰쥐의 간세포 독성에 미치는 영향
장우영(Woo Young Jang),이강노(Kang Ro Lee),지옥표(Ok Pyo Jee),유승조(Seung Jo Yoo),김영중(Young Choong Kim),김선여(Soon Yoo Kim) 대한약학회 1993 약학회지 Vol.37 No.2
alpha-Linolenic acid ethylester, C19 spiroketalenolether polyyne, herniarin and steroid were isolated from the leaves of Artemisia selengesis (Compositae). The structures of the compounds were elucidated on the basis of spectroscopic evidence. Liver protective effects of these constituents were studied using galactosamine and CCl4-induced cytotoxicity in primary cultured rat hepatocytes.
장우영,이강노,Jang, Woo-Young,Lee, Kang-Ro 한국생약학회 1993 생약학회지 Vol.24 No.2
From the ethanol extract of the leaves of Artemisia selengensis a new sesquiterpene endoperoxide, bisabolene-2,5-endoperoxide, has been isolated. The structure of the peroxide was established on the basis of spectroscopic evidence.