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Song, Do Seon,Nam, Soon Woo,Bae, Si Hyun,Kim, Jin Dong,Jang, Jeong Won,Song, Myeong Jun,Lee, Sung Won,Kim, Hee Yeon,Lee, Young Joon,Chun, Ho Jong,You, Young Kyoung,Choi, Jong Young,Yoon, Seung Kew WJG Press 2015 WORLD JOURNAL OF GASTROENTEROLOGY Vol.21 No.8
<P>To investigate the efficacy and safety of transarterial chemoembolization (TACE)-based multimodal treatment in patients with large hepatocellular carcinoma (HCC).</P>
Cho, Young-Seok,Chae, Hiun-Suk,Kim, Hyung-Keun,Kim, Jin-Soo,Kim, Byung-Wook,Kim, Sung-Soo,Han, Sok-Won,Choi, Kyu-Yong WJG Press 2008 WORLD JOURNAL OF GASTROENTEROLOGY Vol.14 No.13
<P>To compare the hemostatic efficacy and safety of two mechanical endoscopic methods: endoscopic band ligation (EBL) and endoscopic hemoclip placement (EHP) in patients with actively bleeding Mallory-Weiss syndrome (MWS).</P>
Procedure-related musculoskeletal symptoms in gastrointestinal endoscopists in Korea.
Byun, Young-Hye,Lee, Jun-Haeng,Park, Moon-Kyung,Song, Ji-Hyun,Min, Byung-Hoon,Chang, Dong-Kyung,Kim, Young-Ho,Son, Hee-Jung,Rhee, Poong-Lyul,Kim, Jae-J,Rhee, Jong-Chul,Hwang, Ji-Hye,Park, Dong-Il,Shim WJG Press 2008 WORLD JOURNAL OF GASTROENTEROLOGY Vol.14 No.27
<P>To determine the prevalence and risk factors of work-related musculoskeletal disorders in gastrointestinal endoscopists in Korea.</P>
Diabetic factors associated with gastrointestinal symptoms in patients with type 2 diabetes.
Kim, Jeong Hwan,Park, Hyung Seok,Ko, Soon Young,Hong, Sung Noh,Sung, In-Kyung,Shim, Chan Sub,Song, Kee-Ho,Kim, Dong-Lim,Kim, Sook Kyung,Oh, Jeeyoung WJG Press 2010 WORLD JOURNAL OF GASTROENTEROLOGY Vol.16 No.14
<P>To determine whether gastrointestinal (GI) symptoms are more frequent in type 2 diabetic patients and to examine which diabetic factors are associated with the symptoms.</P>
AMPK-associated signaling to bridge the gap between fuel metabolism and hepatocyte viability.
Yang, Yoon Mee,Han, Chang Yeob,Kim, Yoon Jun,Kim, Sang Geon WJG Press 2010 WORLD JOURNAL OF GASTROENTEROLOGY Vol.16 No.30
<P>The adenosine monophosphate-activated protein kinase (AMPK) and p70 ribosomal S6 kinase-1 pathway may serve as a key signaling flow that regulates energy metabolism; thus, this pathway becomes an attractive target for the treatment of liver diseases that result from metabolic derangements. In addition, AMPK emerges as a kinase that controls the redox-state and mitochondrial function, whose activity may be modulated by antioxidants. A close link exists between fuel metabolism and mitochondrial biogenesis. The relationship between fuel metabolism and cell survival strongly implies the existence of a shared signaling network, by which hepatocytes respond to challenges of external stimuli. The AMPK pathway may belong to this network. A series of drugs and therapeutic candidates enable hepatocytes to protect mitochondria from radical stress and increase cell viability, which may be associated with the activation of AMPK, liver kinase B1, and other molecules or components. Consequently, the components downstream of AMPK may contribute to stabilizing mitochondrial membrane potential for hepatocyte survival. In this review, we discuss the role of the AMPK pathway in hepatic energy metabolism and hepatocyte viability. This information may help identify ways to prevent and/or treat hepatic diseases caused by the metabolic syndrome. Moreover, clinical drugs and experimental therapeutic candidates that directly or indirectly modulate the AMPK pathway in distinct manners are discussed here with particular emphasis on their effects on fuel metabolism and mitochondrial function.</P>
Malignant mesothelioma of the greater omentum mimicking omental infarction: a case report.
Shin, Min-Kee,Lee, Ok-Jae,Ha, Chang-Yoon,Min, Hyun-Joo,Kim, Tae-Hyo WJG Press 2009 WORLD JOURNAL OF GASTROENTEROLOGY Vol.15 No.38
<P>Mesothelioma develops most commonly in the pleura, and less frequently in the peritoneum. Usually, it manifests as diffuse peritoneal thickening and multiple nodules, and rarely as a solitary mass. We report a rare case of primary malignant mesothelioma of the greater omentum, which mimicked omental infarct. A 54-year-old Korean man was admitted because of severe abdominal pain of sudden onset. A tender mass with indistinct margins was palpated in the upper abdomen. Abdominal ultrasound and computed tomography showed an ill-defined mass in the greater omentum and little ascites in the peri-hepatic space, and neutrophil-dominant exudates were documented on paracentesis. Intravenous antibiotics and analgesics were given for omental infarction with superimposed infection, which resulted in symptomatic improvement. The imaging studies after a week revealed a growing mass and ascites. Laparoscopic surgery was performed and an 8 cm x 3.3 cm greater omental mass was found, with multiple small nodules on the peritoneum, diaphragm, and pelvic cavity wall. Histological examination showed proliferating malignant epithelioid cells that stained strongly for calretinin, which was compatible with malignant mesothelioma. We recommend that primary omental mesothelioma should be included in the differential diagnosis of patients with omental infarction, despite its rarity.</P>
Effect of Lonicerae Flos extracts on reflux esophagitis with antioxidant activity.
Ku, Sae-Kwang,Seo, Bu-Il,Park, Ji-Ha,Park, Gyu-Yeol,Seo, Young-Bae,Kim, Jae-Soo,Lee, Hyeung-Sik,Roh, Seong-Soo WJG Press 2009 WORLD JOURNAL OF GASTROENTEROLOGY Vol.15 No.38
<P>To observe the effects of traditional antiinflammatory medicine Lonicerae Flos (LF) on rat reflux esophagitis (RE) induced by pylorus and forestomach ligation compared with the well-known proton antioxidant, alpha-tocopherol.</P>
Is it possible to differentiate gastric GISTs from gastric leiomyomas by EUS?
Kim, Gwang Ha,Park, Do Youn,Kim, Suk,Kim, Dae Hwan,Kim, Dong Heon,Choi, Cheol Woong,Heo, Jeong,Song, Geun Am WJG Press 2009 WORLD JOURNAL OF GASTROENTEROLOGY Vol.15 No.27
<P>To evaluate the ultrasonography (EUS) features of gastric gastrointestinal stromal tumors (GISTs) as compared with gastric leiomyomas and then to determine the EUS features that could predict malignant GISTs.</P>
La, Jun-Ho,Sung, Tae-Sik,Kim, Hyun-Ju,Kim, Tae-Wan,Kang, Tong-Mook,Yang, Il-Suk WJG Press 2008 WORLD JOURNAL OF GASTROENTEROLOGY Vol.14 No.5
<P>To investigate whether peripheral corticotropin releasing hormone (CRH), which is up-regulated in intestinal inflammation, mediates the post-inflammatory visceral hypersensitivity in a rat model of colitis.</P>
Endoscopic management of occluded metal biliary stents: metal versus 10F plastic stents.
Yoon, Won Jae,Ryu, Ji Kon,Lee, Jung Won,Ahn, Dong-Won,Kim, Yong-Tae,Yoon, Yong Bum,Woo, Sang Myung,Lee, Woo Jin WJG Press 2010 WORLD JOURNAL OF GASTROENTEROLOGY Vol.16 No.42
<P>To compare the efficacy of self-expandable metal stents (SEMSs) with 10F plastic stents (PSs) in the endoscopic management of occluded SEMSs.</P>