Systematics of <i>Hypnea asiatica</i> sp. nov. (Hypneaceae, Rhodophyta) based on morphology and nrDNA SSU, plastid <i>rbcL</i> , and mitochondrial <i>cox1</i>

Geraldino, Paul John L.,Yang, Eun Chan,Sook Kim, Myung,Min Boo, Sung Wiley (John WileySons) 2009 Taxon Vol.58 No.2

Psychosis in Systemic Lupus Erythematosus: Results From an International Inception Cohort Study

Hanly, John G.,Li, Qiuju,Su, Li,Urowitz, Murray B.,Gordon, Caroline,Bae, Sang‐,Cheol,Romero‐,Diaz, Juanita,Sanchez‐,Guerrero, Jorge,Bernatsky, Sasha,Clarke, Ann E.,Wallace, Daniel J. Wiley (John WileySons) 2019 Arthritis & rheumatology Vol.71 No.2

Direct Fabrication of Nanodomes‐Combined Surface Relief Gratings on Azobenzene Polymer Films with Controlled Shapes and Sizes

Kim, Kang‐,Han,Lee, Yong Min,Ryou, Myung‐,Hyun,Jeong, Yong‐,Cheol John WileySons, Inc. 2019 Journal of polymer science Part B, Polymer physics Vol.57 No.12

<P><B>ABSTRACT</B></P><P>In this study, we present nanodomes‐combined surface relief gratings (SRGs) of azopolymer films with controlled shapes and sizes. We investigate the effect of the polarization mode of light interference on leading nanodomes in the conventional SRG patterns. In addition, we also systematically study the relationship between Bragg distance of light interference and shapes of nanodomes. From this, we explain the anisotropic self‐assembled behavior nanodomes in photoaddressable azopolymer films regarding polarization modes as well as spatial confinement effect. © 2019 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. <B>2019</B>, <I>57</I>, 731–737</P>

Stratospheric variability contributed to and sustained the recent hiatus in Eurasian winter warming

Garfinkel, Chaim I.,Son, Seok‐,Woo,Song, Kanghyun,Aquila, Valentina,Oman, Luke D. John WileySons, Ltd 2017 Geophysical research letters Vol.44 No.1

<▼1><P><B>Abstract</B></P><P>The recent hiatus in global‐mean surface temperature warming was characterized by a Eurasian winter cooling trend, and the cause(s) for this cooling is unclear. Here we show that the observed hiatus in Eurasian warming was associated with a recent trend toward weakened stratospheric polar vortices. Specifically, by calculating the change in Eurasian surface air temperature associated with a given vortex weakening, we demonstrate that the recent trend toward weakened polar vortices reduced the anticipated Eurasian warming due to increasing greenhouse gas concentrations. Those model integrations whose stratospheric vortex evolution most closely matches that in reanalysis data also simulate a hiatus. While it is unclear whether the recent weakening of the midwinter stratospheric polar vortex was forced, a properly configured model can simulate substantial deviations of the polar vortex on decadal timescales and hence such hiatus events, implying that similar hiatus events may recur even as greenhouse gas concentrations rise.</P></▼1><▼2><P><B>Key Points</B></P><P><P>Recent Eurasian cooling was associated with stratospheric variability</P><P>Those model integrations whose stratospheric vortex evolution most closely matches that in reanalysis data also simulate a hiatus</P><P>Similar hiatus events could recur even as GHG concentrations rise, but are only properly simulated by stratosphere‐resolving models</P></P></▼2>

Low‐cost and miniaturized metamaterial absorber using 3D printed swastika symbol

Kim, Minseok,Jeong, Heijun,Lim, Daecheon,Ghosh, Saptarshi,Lim, Sungjoon John WileySons, Inc. 2020 MICROWAVE AND OPTICAL TECHNOLOGY LETTERS - Vol.62 No.4

<P><B>Abstract</B></P><P>In this paper, a low‐cost metamaterial (MM) absorber is proposed using 3‐dimensional (3D) printing technology. The unit cell of the proposed MM absorber is motivated from a swastika symbol to minimize the footprint size. For further miniaturization, the unit cell is 3D printed by stacking two blocks. The conductive top patterns are realized by painting with a silver ink. The proposed MM absorber consists of 2 × 4 unit cell array which is loaded in the rectangular waveguide. Its absorptivity is simulated and measured to demonstrate the performance. The simulated and measured absorptivity at 1.91 GHz are 99% and 92%, respectively.</P>

Evaluation of remediation processes for explosive‐contaminated soils: kinetics and Microtox^® bioassay

Oh, Seok‐,Young,Yoon, Hyun‐,Su,Jeong, Tae‐,Yong,Kim, Sang Don John WileySons, Ltd 2016 Journal of chemical technology and biotechnology Vol.91 No.4

<P>BACKGROUNDSoils and sediments near military sites where training regularly occurs are vulnerable to contamination from toxic nitro explosives such as 2,4,6-trinitrotoluene (TNT) and hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). In order to clean up the explosive-contaminated soils, several options have been investigated and evaluated as ex situ remediation processes, including alkaline hydrolysis, subcritical water degradation, zero-valent iron (Fe(0)) reduction, and Fe(0)-assisted Fenton oxidation. The kinetics of the remediation processes were evaluated and the toxicity of treated solutions determined using the Microtox((R)) bioassay. RESULTSKinetically, using four remediation methods, explosives were rapidly degraded in contaminated soils. Under optimal conditions, more than 99% of explosives were destroyed. However, the Microtox((R)) bioassay showed that after degradation of explosives by alkaline hydrolysis, treated solutions did not show any decrease in toxicity, suggesting that hydrolytic products may still be toxic. Similarly, the Fe(0) reduction process did not significantly aid removal of toxicity due to the toxicity of reduction products. In contrast, subcritical water degradation and Fe(0)-assisted Fenton oxidation markedly reduced the toxicity of explosives. When a toxic metal (e.g. Pb in shooting ranges) co-existed with explosives, toxicity still remained after complete degradation of the explosives by subcritical water degradation or Fe(0)-assisted Fenton oxidation, indicating that additional treatment may be needed. CONCLUSIONSResults suggest that, besides removal/degradation of toxic explosives, reduction of toxicity after treatment should be evaluated to select a practical option to remediate explosive-contaminated soils. (c) 2015 Society of Chemical Industry</P>

Improved FBMC/OQAM uplink performance using an antenna array in a highly frequency selective fading channel

Kim, Yekaterina,Ahn, Heungseop,Kim, Daejin,Choi, Seungwon John WileySons, Inc. 2020 MICROWAVE AND OPTICAL TECHNOLOGY LETTERS Vol.62 No.1

<P><B>Abstract</B></P><P>Filter bank multicarrier with offset quadrature amplitude modulation (FBMC/OQAM) is an attractive alternative to orthogonal frequency division multiplexing, as it yields a higher spectral efficiency and robustness to frequency dispersion; however, FBMC/OQAM suffers from multipath interference owing to the absence of the cyclic prefix, especially in the signal environments of widely spread multipaths. Although conventional techniques such as multiple‐input multiple‐output along with equalization can combat multipath fading, these techniques do not effectively resolve the multipath interference unless each subcarrier channel can be assumed to be of a flat fading. This article presents a systematic procedure of applying a receive antenna array to FBMC/OQAM systems that removes the multipath interferences using a nicely‐shaped beam pattern for each of the multipaths associated with a severe frequency selectivity. The performance of the proposed array system has been demonstrated in terms of its bit error rate in the adverse multipath‐spread environment of the Extended Typical Urban model of the 3rd Generation Partnership Project, in which each subcarrier channel suffers from a severe frequency‐selective fading. Using various computer simulations, we found that the proposed array system can completely resolve multipath interferences with an array of <I>N</I> = 10, 16, and 22 when Δ<I>θ</I> = 15°, 10°, and 5°, respectively, where <I>N</I> and Δ<I>θ</I> denote the number of antennas in each subarray and the interpath direction of arrival difference, respectively. In addition, the proposed array system also provides a signal‐to‐noise ratio gain that is proportional to <I>N</I>, once the multipath interferences are successfully resolved.</P>

Resistin derived from diabetic perivascular adipose tissue up-regulates vascular expression of osteopontin via the AP-1 signalling pathway

Park, So Youn,Kim, Kyu Hee,Seo, Kyo Won,Bae, Jin Ung,Kim, Yun Hak,Lee, Seung Jin,Lee, Won Suk,Kim, Chi Dae John WileySons, Ltd 2014 The Journal of pathology Vol.232 No.1

<P>Perivascular adipose tissue (PVAT) is implicated in the development of vascular diseases; however, the roles of PVAT on OPN expression in diabetic vasculature remain to be determined. This study investigated the role of adipokines derived from diabetic PVAT in regulating the vascular expression of OPN and explored the mechanisms involved. Aortic sections of ob/ob and high-fat diet (HFD)-induced obese (DIO) mice showed an increased expression of OPN, which was paralleled by increased amounts of PVAT characterized by enlargement of adipocytes. In the earlier phase of HFD feeding, macrophage infiltration was mainly localized to the area of PVAT at which adipocytes were enlarged, suggesting a potential link of activated adipocytes to macrophage infiltration. PVAT sections of ob/ob and DIO mice revealed a significantly greater number of macrophages with increased expression of adipokines, including resistin and visfatin. The distribution of resistin in PVAT mostly co-localized with macrophages, while visfatin was expressed in macrophages and other cells. In <I>in vitro</I> studies, OPN expression in vascular smooth muscle cells (VSMCs) co-cultured with PVAT of DIO mice was significantly increased, which was attenuated by a resistin-neutralizing antibody. Likewise, resistin up-regulated expression of <I>OPN</I> mRNA and protein in cultured VSMCs and the pivotal role of AP-1 in resistin-induced OPN transcription was demonstrated. Resistin produced by PVAT plays a pivotal role in the up-regulated expression of OPN in the diabetic vasculature via a signalling pathway that involves activation of AP-1. © 2013 The Authors. <I>Journal of Pathology</I> published by John Wiley & Sons Ltd on behalf of Pathological Society of Great Britain and Ireland.</P>

Integration of microbial and chemical processing for a sustainable metallurgy

Ilyas, Sadia,Kim, Min‐,seuk,Lee, Jae‐,chun John WileySons, Ltd 2018 Journal of chemical technology and biotechnology Vol.93 No.2

<P>Bioprocessing for the recovery of metal from divergent resources using the microbial strategy has emerged as a green technology in metallurgical operations. The limitations to maintain the ideal condition for bacterial growth with slow kinetics, however, have been considered as major obstacles to bioprocessing being implemented more widely. This can be overcome by integrating the microbes with a chemical processing route. The available reports on recent developments in hybrid bio-chemical processing of both primary and secondary resources have presented promising results, exhibiting the potential for use in large-scale metallurgy. In this context, reviewing the factors of the hybrid process would benefit from knowledge acquired in fundamental studies. The present review focuses on bio-chemical process integration using eco-friendly design tools for treating the difficult to extract resources and complex spent materials as well. Furthermore, the potential of hybrid technology has been evaluated by establishing an economic model as a case study which encompasses features of economic development, environmental consideration and societal matters to achieve process sustainability. (c) 2017 Society of Chemical Industry</P>

Pleural or pericardial metastasis: A significant factor affecting efficacy and adverse events in lung cancer patients treated with PD‐1/PD‐L1 inhibitors

Kang, Da Hyun,Chung, Chaeuk,Kim, Ju‐,Ock,Jung, Sung Soo,Park, Hee Sun,Park, Dong Il,Jung, Sun Young,Park, Myoungrin,Lee, Jeong Eun John WileySons Australia, Ltd 2018 Thoracic cancer Vol.9 No.11

<P><B>Background</B></P><P>Immunotherapy is a new paradigm for the treatment of non‐small‐cell lung cancer (NSCLC), and targeting the PD‐1 or PD‐L1 pathway is a promising therapeutic option. Although PD‐1/PD‐L1 inhibitors are more effective than standard chemotherapy in lung cancer, clinicians are afraid to actively use them because of hyperprogression and pseudoprogression. The aim of this study was to investigate the factors associated with tumor response and serious outcomes.</P><P><B>Methods</B></P><P>We retrospectively collected the medical records of 51 patients with advanced NSCLC who received PD‐1/PD‐L1 inhibitors between January 2016 and February 2018.</P><P><B>Results</B></P><P>The mean patient age was 63.9 years, and 72.5% (37/51) were male. Most (92.2%, 47/51) had received previous systemic treatment. The overall response rate was 21.6% (11/51). The response rate was significantly lower in patients with pleural or pericardial metastasis than in patients without pleural or pericardial metastasis (4.3% vs. 35.7%; <I>P</I> = 0.007). Patients with pleural or pericardial metastasis had a significantly higher rate of adverse events of any grade (91.3% vs. 50.0%; <I>P</I> = 0.002) and grade 3–5 adverse events (52.2% vs. 25.0%; <I>P</I> = 0.046).</P><P><B>Conclusion</B></P><P>Pleural or pericardial metastasis is a significant factor affecting the efficacy and rate of adverse events in advanced NSCLC patients treated with PD‐1/PD‐L1 inhibitors. Clinicians should pay attention to the use of immune checkpoint inhibitors in lung cancer patients with pleural or pericardial metastasis.</P>