Prevalence and molecular analysis of glucose-6-phosphate dehydrogenase deficiency in Chin State, Myanmar

Ja Moon Aung,Moon Zin,VanBik Dorene,Dinzouna-Boutamba Sylvatrie-Danne,이상현,Ring Zau,정동일,홍연철,구윤경 대한기생충학ㆍ열대의학회 2023 The Korean Journal of Parasitology Vol.61 No.2

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is caused by X-linked recessive disorderliness. It induces severe anemia when a patient with G6PD deficiency is exposed to oxidative stress that occurs with administration of an antimalarial drug, primaquine. The distribution of G6PD deficiency remains unknown while primaquine has been used for malaria treatment in Myanmar. This study aimed to investigate the prevalence of G6PD deficiency and its variants in Chin State, Myanmar. Among 322 participants, 18 (11 males and 7 females) demonstrated a G6PD deficiency. Orissa variant was dominant in the molecular analysis. This would be related to neighboring Indian and Bangladeshi population, in which Orissa variant was also reported as the main mutation type. The screening test for G6PD deficiency before primaquine treatment appears to be important in Myanmar.

The Adsorption of Cu(II), Co(II), Ni(II) from Aqueous Solution onto Activated Carbon Fibers and the Effect of Picolinic Acid

Sang Moon Lee 한국화학공학회 1999 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.37 No.1

SDN-Based Self-Organizing Energy Efficient Downlink/Uplink Scheduling in Heterogeneous Cellular Networks

MOON, Seungil,OO, Thant Zin,KAZMI, S. M. Ahsan,PARK, Bang Ju,HONG, Choong Seon 'Institute of Electronics, Information and Communi 2017 IEICE transactions on information and systems Vol.100e.d No.5

<P>The increase in network access devices and demand for high quality of service (QoS) by the users have led to insufficient capacity for the network operators. Moreover, the existing control equipment and mechanisms are not flexible and agile enough for the dynamically changing environment of heterogeneous cellular networks (HetNets). This non-agile control plane is hard to scale with ever increasing traffic demand and has become the performance bottleneck. Furthermore, the new HetNet architecture requires tight coordination and cooperation for the densely deployed small cell base stations, particularly for interference mitigation and dynamic frequency reuse and sharing. These issues further complicate the existing control plane and can cause serious inefficiencies in terms of users' quality of experience and network performance. This article presents an SDN control framework for energy efficient downlink/uplink scheduling in HetNets. The framework decouples the control plane from data plane by means of a logically centralized controller with distributed agents implemented in separate entities of the network (users and base stations). The scheduling problem consists of three sub-problems: (i) user association, (ii) power control, (iii) resource allocation and (iv) interference mitigation. Moreover, these sub-problems are coupled and must be solved simultaneously. We formulate the DL/UL scheduling in HetNet as an optimization problem and use the Markov approximation framework to propose a distributed economical algorithm. Then, we divide the algorithm into three sub-routines for (i) user association, (ii) power control, (iii) resource allocation and (iv) interference mitigation. These sub-routines are then implemented on different agents of the SDN framework. We run extensive simulation to validate our proposal and finally, present the performance analysis.</P>

18세기 이후 유럽의 뮤지엄 건축의 동선체계에 나타난 보편적 경향과 다원적 경향에 관한 연구

문정묵,임채진 대한건축학회 2004 대한건축학회논문집 Vol.20 No.4

Since the 18th century the museums in Europe have accepted the social demand of the publicity and have played a role of social education and it lasted to the present. Recently, the society began to change it's direction. It is from the Universalism to the Pluralism. The Universalism is due to democratic society after 'the Civil Revolution' and standardized social system after 'the Industrial Revolution' The Pluralism that starts with the decrease of the modern society is about the diversity and the activation of identity which has been disregarded since the Modernism. This study is to analyze and to clarify how the museum's educational environment which had begun since the 18th century has been changed since 1990 and how these are related to the social alteration from the Universalism to the Pluralism. As a result of this study, it was confirmed that there had been a simple circulation system and a unified spatial experience in the museum of Europe since 18th century to 1980's(ph1) while there had been a complex circulation system and a diverse spatial experience in the museum of Europe after 1990's(ph2). These mean that the museum of ph1 gave a unified social education to the visitors and they came to have a similar knowledge and emotion after their seeing the exhibition material while the museums of 'ph2' gave a diverse one and the visitor came to have a different knowledge and emotion to the same exhibition material. The museum which gives a unified social education is to produce a unified thoughts of people and it is because the social direction is the Universalism. In addition to this, the museum of diverse social education is to produce people of diversity and it is related to the Pluralism.

Nonlinear Model-Based Robust Control of a Nuclear Reactor Using Adaptive PIF Gains and Variable Structure Controller

Park, Moon-Ghu,Cho, Nam-Zin Korean Nuclear Society 1993 Nuclear Engineering and Technology Vol.25 No.1

A Nonlinear model-based Hybrid Controller (NHC) is developed which consists of the adaptive proportional-integral-feedforward (PIF) gains and variable structure controller. The controller has the robustness against modeling uncertainty and is applied to the trajectory tracking control of single-input, single-output nonlinear systems. The essence of the scheme is to divide the control into four different terms. Namely, the adaptive P-I-F gains and variable structure controller are used to accomplish the specific control actions by each terms. The robustness of the controller is guaranteed by the feedback of estimated uncertainty and the performance specification given by the adaptation of PIF gains using the second method of Lyapunov. The variable structure controller is incorporated to regulate the initial peak of the tracking error during the parameter adaptation is not settled yet. The newly developed NHC method is applied to the power tracking control of a nuclear reactor and the simulation results show great improvement in tracking performance compared with the conventional model-based control methods.

왕복노즐을 이용한 분무적층공정의 컴퓨터 시뮬레이션

이진형,문병철 대한금속재료학회(대한금속학회) 1994 대한금속·재료학회지 Vol.32 No.8

A flat plate can be manufactured by a new spray deposition method with a reciprocating spray nozzle and moving substrate. The shape and the temperature of the depostit. The shape and the temperature of the depostit produced by this process is analyzed by numerical method. An integral model for this spray deposition process has been developed and some necessary data of the spray deposition apparatus are measured experimentally. Governing equation of the temperature change of deposit is one dimensional heat conduction equation and solved by Fully Implicit FDM and TDMA. The unique feature of this process is the variation of deposition rate with time due to the variation of the position of the spray nozzle. As deposition rate is varying, the mesh size of the finite difference method also varies. The thickness of the deposit is governed by substrate speed and the waviness is governed by the reciprocating speed of the nozzle. Since the cooling rate of the deposit is gevened mainly by the deposit thickness, the substrate speed is its main controlling factor. Two parameters, Semi-Liquid Film Formation Thickness(SLFFT) and Maximum Liquid Fraction(MLF) are proposed for the prediction of deposit microstructure.

금속간화합물 TiAl 의 고온산화거동 및 기계적성질에 미치는 Yttrium 첨가 Ll2 (Al, Cr) 3Ti 코팅의 효과

위당문,오명훈,이호년,박정용,박진민 대한금속재료학회(대한금속학회) 1999 대한금속·재료학회지 Vol.37 No.4

The oxidation behaviors and the mechanical properties of TiAl alloys coated with the Al-21Ti-23Cr and the Al-21Ti-23Cr-0.lY films were investigated. A small addition of yttrium to the coating material was, effective in the improvement of the oxidation resistance of the Ti-48Al. From the scratch test, specimen coated with the Al-21Ti-23Cr-0.1Y film had better adhesion between the Al₂O₃ scale and the coating layer than one coated with the Al-21Ti-23Cr film. And AFM study showed that the Al₂O₃,surface of the Al-21Ti-23Cr-0.1Y coating is more smooth than one of the Al-21Tr-23Cr coating after isothermal oxidation; Thus, it is suggested that this excellent oxidation resistance is attributable to the excellent adhesion between the Al₂O₃ scale and the Al-21Ti-23Cr-0.1Y film and the smooth Al₂O₃ surface of the Al-21Ti-23Cr-0.1Y coating. From the tensile test, it was found that AI-21Ti-23Cr-0.1Y coating enables the TiAl to maintain more effectively its tensile properties in an oxidizing environment than the Al-21Ti-23Cr coating. Moreover, the specimen coated with the Al-21Ti-23Cr-0.1Y film showed lower creep rate and longer time to rupture than the specimen without coating, under the constant stress of 200 ㎫ at 1123 K in air. Therefore. it could be assumed that the Al-21Ti-23Cr-0.1Y alloy was prospective as an oxidation-resistant coating material for TiAl alloys.

Dioscorea Extract (DA-9801) Modulates Markers of Peripheral Neuropathy in Type 2 Diabetic db/db Mice

( Eun Jung Moon ),( Sung Ok Lee ),( Tong Ho Kang ),( Hye Ju Kim ),( Sang Zin Choi ),( Mi Won Son ),( Sun Yeou Kim ) 한국응용약물학회 2014 Biomolecules & Therapeutics(구 응용약물학회지) Vol.22 No.5

The purpose of this study was to investigate the therapeutic effects of DA-9801, an optimized extract of Dioscorea species, on diabetic peripheral neuropathy in a type 2 diabetic animal model. In this study, db/db mice were treated with DA-9801 (30 and 100 mg/kg, daily, p.o.) for 12 weeks. DA-9801 reduced the blood glucose levels and increased the withdrawal latencies in hot plate tests. Moreover, it prevented nerve damage based on increased nerve conduction velocity and ultrastructural changes. Decrease of nerve growth factor (NGF) may have a detrimental effect on diabetic neuropathy. We previously reported NGF regulatory properties of the Dioscorea genus. In this study, DA-9801 induced NGF production in rat primary astrocytes. In addition, it increased NGF levels in the sciatic nerve and the plasma of type 2 diabetic animals. DA-9801 also increased neurite outgrowth and mRNA expression of Tieg1/Klf10, an NGF target gene, in PC12 cells. These results demonstrated the attenuation of diabetic peripheral neuropathy by oral treatment with DA-9801 via NGF regulation. DA-9801 is currently being evaluated in a phase II clinical study.

제올라이트를 함유한 부분활성화된 PAN복합체 섬유의 제조에 관한 연구

오원진,설용건,정경택,문제권,황덕근,이화섭 한국화학공학회 1998 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.36 No.5

아크릴로니트릴모노머를 전구체로하여 제올라이트를 함유한 부분활성화 PAN 복합체 섬유를 제조하였다. 중량평균 분자량 630,000이고, 다분산지수가 1.30인 방사 dope를 건습식 방사법(dry-jet wet spinning technique)으로 방사하였다. 제올라이트를 함유한 35-40㎛ 두께의 PAN섬유는 건습열 연신과정을 통해 배향도가 증가되었다, 같은 조건에서 얻어진 PAN섬유에 비하여 제올라이트를 함유한 PAN 복합체 섬유는 89%의 인장강도를 나타내었다. 고리화와 부분활성화 상태는 적외선분광 분석법과 X선회절 분석법을 이용하여 확인하였다. PAN 섬유의 부분활성화 이후에도 제올라이트의 함유에 따른 특성 피이크를 X선회절 분석법을 이용하여 확인할 수 있었다. 제올라이트를 함유한 PAN 복합체 섬유는 새로운 유무기 복합 흡착제로 사용을 기대할 수 있을 것으로 사료된다. Partially activated polyacrylonitrile(PAN) composite fiber containing zeolite particle was prepared by using acrylonitrile(AN) as a precursor. Weight average molecular weight(Mw) and polydispersity index of spinning dope was 630,000 and 1.30 respectively. Dry-jet wet spinning technique was used for making PAN composite fiber. During, the dry-jet wet spinning process, PAN composite fiber of 35-45㎛ in diameter shows increased orientation. Initial elastic modulus of PAN composite fiber containing zeolite particles was 89 % of PAN fiber at the same experimental condition. The cyclization and activated state of PAN fiber were conformed by Fourier transform infrared(FT-IR) spectroscopy and X-ray diffraction(XRD). After the activation process, characteristic peaks of PAN composite fiber could be observed due to the incorporation of zeolite particles from XRD. Partially activated PAN composite fiber containing zeolite particles is expected to use as an organic-inorganic composite absorbent.

金劑(gold salt) 및 estradiol이 家兎의 滑膜 및 骨髓에 미치는 影響에 關한 硏究

李光鎭(Kwang Zin Rhee),韓文植(Moon Sik Han) 대한정형외과학회 1977 대한정형외과학회지 Vol.12 No.4