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Potential of the Quantitative Trait Loci Mapping Using Crossbred Population
Yang, Shulin,Zhu, Zhengmao,Li, Kui Asian Australasian Association of Animal Productio 2005 Animal Bioscience Vol.18 No.12
In the process of crossbreeding, the linkage disequilibria between the quantitative trait loci (QTL) and their linked markers were reduced gradually with increasing generations. To study the potential of QTL mapping using the crossbred population, we presented a mixed effect model that treated the mean allelic value of the different founder populations as the fixed effect and the allelic deviation from the population mean as random effect. It was assumed that there were fifty QTLs having effect on the trait variation, the population mean and variance were divided to each QTL in founder generation in our model. Only the additive effect was considered in this model for simulation. Six schemes (S1-S6) of crossbreeding were studied. The selection index was used to evaluate the synthetic breeding value of two traits of the individual in the scheme of S2, S4 and S6, and the individuals with high selection index were chosen as the parents of the next generation. Random selection was used in the scheme of S1, S3 and S5. In this study, we premised a QTL explained 40% of the genetic variance was located in a region of 20 cM by the linkage analysis previously. The log likelihood ratio (log LR) was calculated to determine the presence of a QTL at the particular chromosomal position in each of the generations from the fourth to twentieth. The profiles of log LR and the number of the highest log LR located in the region of 5, 10 and 20 cM were compared between different generations and schemes. The profiles and the correct number reduced gradually with the generations increasing in the schemes of S2, S4 and S6, but both of them increased in the schemes of S1, S3 and S5. From the results, we concluded that the crossbreeding population undergoing random selection was suitable for improving the resolution of QTL mapping. Even experiencing index selection, there was still enough variation existing within the crossbred population before the fourteenth generation that could be used to refine the location of QTL in the chromosome region.
Weighting factor design based on SVR–MOPSO for finite set MPC operated power electronic converters
Yonglu Liu,Zhengmao Yang,Xubin Liu,Hanbing Dan,Wenjing Xiong,Tao Ling,Mei Su 전력전자학회 2022 JOURNAL OF POWER ELECTRONICS Vol.22 No.7
Selecting weighting factors is a challenge for the finite set model predictive control (FS-MPC). Based on the support vector regression (SVR) algorithm and the multi-objective particle swarm optimization (MOPSO) algorithm, this paper proposes a new weighting factor design principle. SVR is used to establish the functional relationship between the input weighting factors and the output performance indexes (such as the average switching frequency (fsw) and the total harmonic distortion of the output voltage). Even in the case of small samples, this can provide accurate performance index estimates for any combination of weighting factors. The established SVR function is taken as the fitness function. Then, MOPSO is used to search for Pareto optimal weighting factor combinations. The proposed method can converge in a few steps and does not require tedious calculations. Moreover, it is applicable to optimization problem with two or more weighting factors for arbitrary topology models. It also provides a range of optimal weighting factor solution sets. Finally, the proposed methodology is verified on a practical weighting factor design problem in a FS-MPC regulated voltage source inverter. Experimental results confirm the correctness of the theoretical analysis.
Li, Changchun,Wang, Zhigang,Liu, Bang,Yang, Shulin,Zhu, Zhengmao,Fan, Bin,Yu, Mei,Zhao, Shuhong,Li, Kui Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.4
The genetic diversities and relationships of 10 Chinese indigenous pig breeds and three exotic pig breeds have been evaluated using 26 microsatellites recommended by the Food and Agriculture Organization & the International Society of Animal Genetics (FAO-ISAG). The allele frequencies, genetic heterozygosity (H) and polymorphism information content (PIC) have been calculated. The results showed that genetic diversity of Chinese indigenous pig breeds is higher than that of the introduced pig breeds. The clustering of 10 breeds is generally consistent with their geographical distribution.