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      • KCI등재

        A Novel Natural Dye Derivative for Natural Fabric Supercritical Carbon Dioxide Dyeing Technology

        Jinsong Wu,Hongjuan Zhao,Mingyue Wang,Weiru Zhi,Xiaoqing Xiong,Laijiu Zheng 한국섬유공학회 2019 Fibers and polymers Vol.20 No.11

        The supercritical carbon dioxide (SC-CO2) dyeing technology is a green dyeing technology, and the usage ofnatural dye makes SC-CO2 dyeing technology safer and more environment-friendly. Nevertheless, after using natural dye inSC-CO2 dyeing, the color depth and fastness of dyed natural fabric are poor. In this study, alkyl and hydroxyalkyl groupswere grafted onto alizarin, which is a natural dye, to elevate the color depths and fastness of alizarin-derivative-dyed naturalfabric. The results demonstrate that the color depths of alkyl-alizarin-dyed and hydroxyalkyl-alizarin-dyed natural fabricswere increased. This has to do with the increase in the solubilities of alkyl alizarin and hydroxyalkyl alizarin in SC-CO2. Thehydroxybutyl-alizarin-dyed wool displayed the best color depth (K/S value: 6.44). And the hydroxyalkyl-alizarin-dyednatural fabric showed good washing fastness and rubbing fastness (about 4-5 level), because that hydroxyalkyl alizarin couldbe linked by a covalent bond to the natural fabric.

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        Analysis of the effect of Rhodopseudomonas palustris on the lead exposure rat model using 1H-NMR-based metabolomics of urine and plasma

        Chai Shutong,Zheng Ziyun,Liu Yani,Liang Yanhui,Yang Hong,Chen Jie,Bai Hongjuan,Yang Guan-e 대한독성 유전단백체 학회 2023 Molecular & cellular toxicology Vol.19 No.2

        Background Rhodopseudomonas palustris had the eff ect of adsorbing and removing lead ions. Metabolomics is a comprehensive analysis based on several metabolites or biomarkers. Objective The paper aimed to investigate the restorative eff ect and the potential mechanisms of R. palustris in rats with the lead exposure model using 1 H-NMR metabolomics. Results Nine endogenous metabolites from rat plasma and 13 endogenous metabolites from rat urine were identifi ed as potential biomarkers of the symptoms of lead poisoning. The changes of metabolites levels in the plasma included lower levels of valine, acetoacetate, and N-acetyl-glycoprotein and a higher concentration of lactate, acetate, creatine, threonine, glutamine, and asparagine in model group compared with control group. Furthermore, increased citrate, succinate, dimethylamine, pyruvate, acetoacetate, α -oxoglutarate and asparagine, accompanied by decreased LDL/VLDL, taurine, creatinine, glucose and hippurate levels were observed in the model group compared with the control group in the urine. Biochemical parameters and histopathology examination dovetailed well with the metabolomics data. Treatment with R. palustris at a certain degree returned the levels of these metabolites to normal levels. Plasma and urine metabolomic analysis showed changes associated with energy metabolism, amino acids and fatty acid metabolism of lead exposure rats. Conclusion The eff ects of removing lead ions of R. palustris in rats with lead exposure were confi rmed. This research demonstrated that 1 H-NMR-based metabolomics was a promising tool to identify potential biomarkers and unravel protective eff ect mechanisms of R. palustris in lead poisoning rats.

      • KCI등재

        One-step solvothermal synthesis of poly(arylene ether nitrile) decorated magnetic composite for methylene blue adsorption from aqueous solution

        Zhou Xuefei,Miao Wei,Cheng Wenxi,Lin Haowei,Lin Haowei,Zheng Hongjuan,Cheng Qiaohuan,Wang Renjie,Yao Chenxue,Liu Xiaobo 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.6

        A series of poly(arylene ether nitrile) containing versatile carboxyl and sulfonic groups (CSPEN) were magnetically functionalized by ferroferric oxide (Fe3O4), and the obtained magnetic adsorbents (Fe3O4/CSPEN) were used to remove methylene blue (MB) dye from aqueous solution. The systematical characterizations that including scanning electron microscope (SEM), X-ray powder diffractometer (XRD), X-ray photoelectron spectroscopy (XPS), vibrating sample magnetometer (VSM), Fourier transform infrared (FTIR) certified that the Fe3O4/CSPEN possessed versatile functional groups and magnetic separation properties. The batch adsorption studies revealed that the Fe3O4/CSPEN not only displayed high selective adsorption ability for cationic MB in the presence of anionic MO, but also exhibited a removal efficiency as high as 98.2%. Besides, the adsorption kinetics and isotherm matched well with pseudo-second-order model and Langmuir model, respectively, and the maximum adsorption capacity of Fe3O4/CSPEN for MB was 92.029 mg/g. The FTIR and Brunauer-Emmett-Teller (BET) analyses confirmed that the outstanding adsorption capacity of Fe3O4/CSPEN was attributed to their own microporous structure and the electrostatic interaction with MB. Therefore, the modified magnetic adsorbent can be used to selectively remove cationic dye from aqueous solution.

      • KCI등재

        Hepatitis B Virus Core Protein Mediates the Upregulation of C5α Receptor 1 via NF-κB Pathway to Facilitate the Growth and Migration of Hepatoma Cells

        Fanyun Kong,Yukai Tao,Dongchen Yuan,Ning Zhang,Qi Li,Tong Yu,Xiaoying Yang,Delong Kong,Xiaohui Ding,Xiangye Liu,Hongjuan You,Kuiyang Zheng,Renxian Tang 대한암학회 2021 Cancer Research and Treatment Vol.53 No.2

        Purpose C5α receptor 1 (C5ΑR1) is associated with the development of various human cancers. However, whether it is involved in the development of hepatitis B virus (HBV)–related hepatocellular carcinoma (HCC) is poorly understood. We explored the expression, biological role, and associated mechanisms of C5AR1 in HBV-related hepatoma cells. Materials and Methods The expression of C5ΑR1 mediated by HBV and HBV core protein (HBc) was detected in hepatoma cells. The function of nuclear factor кB (NF-κB) pathway in HBc-induced C5AR1 expression was assessed. The roles of C5ΑR1 in the activation of intracellular signal pathways, the upregulation of inflammatory cytokines, and the growth and migration of hepatoma cells mediated by HBc, were investigated. The effect of C5α in the development of HCC mediated by C5AR1 was also measured. Results C5ΑR1 expression was increased in HBV-positive hepatoma cells. Dependent on HBc, HBV enhanced the expression of C5ΑR1 at the mRNA and protein levels. Besides, HBc could promote C5ΑR1 expression via the NF-κB pathway. Based on the C5ΑR1, HBc facilitated the activation of JNK and ERK pathways and the expression and secretion of interleukin-6 in hepatoma cells. Furthermore, C5ΑR1 was responsible for enhancing the growth and migration of hepatoma cells mediated by HBc. Except these, C5α could promote the malignant development of HBc-positive HCC via C5AR1. Conclusion We provide new insight into the mechanisms of hepatocarcinogenesis mediated by HBc. C5ΑR1 has a significant role in the functional abnormality of hepatoma cells mediated by HBc, and might be utilized as a potential therapeutic target for HBV-related HCC.

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