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Research on the Algorithm Optimization of Improved Ant Colony Algorithm- LSACA
Yunheng Liu 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.3
The ant colony algorithm is an algorithm which is used to find the optimal path. As a kind of bionic evolutionary algorithm, the ant colony algorithm is inspired by the real ant colony foraging mechanisms. Firstly, this paper introduces the basic model of the ant colony algorithm. Then, aiming at the shortcomings of the ant colony algorithm, we propose a new probability formula of the optimal path and the new formula of the pheromone update. In addition, we combine the traditional ant colony algorithm with the local search algorithm and propose the improved ant colony algorithm. It is the LSACA algorithm. In the experimental analysis, we set and analyze the parameters of the algorithm. Then, we compare with the traditional algorithm to prove the feasibility and the effectiveness of the algorithm.
Xiaohua Liu,Zhenlin Hu,Qirong Shi,Huawu Zeng,Yunheng Shen,Huizi Jin,Wei-Dong Zhang 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.7
Radix Tinosporae is a herb widely used in traditional Chinese medicine for the treatment of various inflammatory diseases. In the present study, its anti-inflammatory and antinociceptive activities were investigated. The ethanol extract of Radix Tinosporae exhibited significant inhibitory effects on xylene-induced ear edema and acetic acid-induced writhing in mice. Using bioassay-guided fractionation, the n-butanol fraction was determined as the active fraction. Further purification of the most active n-butanol fraction led to the isolation of three compounds, palmatine, columbamine and columbinyl glucoside. All three compounds showed inhibitory activities on xylene-induced ear edema, but only palmatine and columbamine exhibited significant inhibitory effects on acetic acid-induced writhing. In addition, palmatine and columbamine markedly inhibited in vitro production of nitric oxide and nuclear factor-κB activation in RAW264.7 macrophage cells in response to lipopolysaccharide or tumor necrosis factor α stimulation. These results provide justification for the utilization of Radix Tinosporae in Chinese folk medicine for the treatment of inflammatory diseases.