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흰쥐에서의 카르복시메칠셀룰로오스나트륨과 겔란검 혼합겔의 유착방지 효과
권윤환,이시범,이정권,박용덕,박정숙,황성주 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.6
The aim of the present study was to investigate the efficacy of a mixed gel formulation composed of sodium carboxymethyl cellulose and gellan gum (Na-CMC gel) for the prevention of adhesions after laminectomv. The anti-adhesive effect of the Na-CMC gel was tested in a controlled randomized study using an animal model of lumbar laminectomv. The animals (60 female Sprague-Dawlev rats) were randomly allocated into two treatment groups to receive the Na-CMC gel on the injured area or no gel (control). The incidence of adhesions and their grade were blindly evaluated at 4. 8 and 12 weeks after surgery. The amount of scar tissue and tenacity were grossly reduced by the Na-CMC gel at postoperative 4. 8. and 12 weeks. The mean adhesion scores were 0.75. 125. and 1.38 at 4. 8. and 12 weeks in the gel-treated group. respectively. No significant inflammatory reaction was observed and the healing of wound was not affected by the Na-CMC gel. The Na-CMC gel reduced the amount of scar formation and tenacity in rat laminectomv model without affecting the healing of operation wound and other complications. Therefore. the Na-CMC gel may be the potential to prevent postsurgical adhesions in clinical state.
사회 인구학적 변인과 부모의 스포츠참여에 따른 자녀의 체육학습 태도
권윤정,김경숙 이화여자대학교 동작과학연구소 2004 이화체육논집 Vol.8 No.-
The main object of this study is to find out how socio-demographic variable and parents participation in sports affect the physical education learning attitude of students. Furthermore, this reports primary purpose is to provide new data and materials for future physical education classes. To achieve such a study aim, the subjects students(518) were chooses in the 2 grader middle schools located on Seoul, classifying in to Gangnam and Gangbuk. The statistics employed this study are the frequent analysis, t-test, One-Way ANOVA and Scheff test. In light of the above research method and process, the following are the analysis results. First, according to the socio-demographic variable(with the exemption of the age of parents) each low primary factors perception, interest, confidence, concentration, and self regulating of physical education learning attitude showed significant difference. Secondly, parents participation in sports greatly influenced the physical education learning attitude(perception, interest, confidence, concentration, and self regulating) of students showed significant difference.
이찬형,윤현숙,박연준,권종대,노기철,장성환 한국환경과학회 2002 한국환경과학회지 Vol.11 No.12
This study was conducted to determine the contents of heavy metals in leaves of roadside trees according to different growth stages in Daegu city. The orders of heavy metal contents in leaves of roadside tree and soil were Fe〉Mn〉Zn〉Pb〉Cu〉Cr〉Cd and Fe〉Mn〉Zn〉Cu〉Pb〉Cr〉Cd, respectively. The contents of heavy metals in leaves of roadside trees and soil showed an increasing tendency as the levels of traffic volume increased. The contents of heavy metals in leaves on October were higher than those on May.
아동의 창의성과 아동이 지각한 부모 양육태도에 관한 연구
권영실,권인옥,김은진,박상미,신미경,유계숙,윤보숙,진혜경,차동숙,최병수 연세대학교 생활과학대학 1986 婦學 Vol.19 No.-
The research is intended to study the sex difference of the parents rearing attitude and of the creativity of children and relationship between the rearing attitude of parents which are perceived by children and creativity of children. For this purpose, selected three primary school in Seoul, and random sampled 150 students of 5 th grade which are 80 boys and 70 girls. We made reference to “General Standarization of Creativity Inspection for Primary School” written by Wonsik, Jeong and Yeong Duck, Lee on 1981. and “Diagnosis Inspection of Relation between Parent and Children for Children” written by Ki Seon, Oh on 1965, for our tools of research. Summarizing the research, derive the result as follows: 1. For the major factor of creativity between boys and girls, boys are superior in fluency. 2. In opinions of the rearing attitude of perents which perceived by children are not significant different with sexes. 3. For the correlation of between the major factor of creativity and the type of parents rearing attitude show the significant correlation as follows Flexibility-interference, Flexibilityuneasiness, Flexibility―favoritism, Flexibility―blind adherence, Flexibility―discrepancy, Originality―blind adherence, Originality―discrepancy, Originality―interference, Originality―uneasiness.
Cho, Eun Sook,Jin, Byung Rae,Sohn, Hung Dae,Choi, Kwang Ho,Kim, Soung Ryul,Kang, Seok Woo,Yun, Eun Young,Kim, Sang Hyun,Kim, Keun Young,Je, Yeon Ho,Kang, Seok Kwon 한국잠사학회 1998 한국잠사곤충학회지 Vol.40 No.2
To construct transfurmed Bm5 cells, Autographa californica nuclear polyhedrosis virus(AcNPV) IE1 gene, an immediate early viral gene was firstly used in this study. AcNPV IE1 gene, which shares on 95.3% nucleotide sequence homology with Bombyx mori nuclear polyhedrosis virus (BmNPV) IE1 gene, was isolated and cloned into pBluescript. Neomycin gene from pKO-neo was inserted under the control of the IE1 promoter to yield pAcIE1-neo. The plasmid pAcIE1-neo was transfected into Bm5 or Sf9 cells, and neomycin-resistant cells were selected in TC100 medium containing 10% fetal bovine serum (FBS) and 1 mg/ml G4l8 for two weeks. Individual clones were picked and each was amplified for further characterization. The genomic DNA from neomycin-resistant cells was isolated and characterized by PCR using AcNPV IEI gene-specific primers and by Southern blot analysis using neomycin gene probe. We concluded that AcNPV IE1 gene was functional in B. mori-derived Bm5 cells as well as Spodoptera fugjprrda-derived Sf9 cells to produce stably-transformed insect cells
Yun, Song-Joong,Lee, Myong-Chul,Kwon, In-Sook,Kim, Tae-San,Go, Seung-Joo The Korean Society of Crop Science 1994 Korean journal of crop science Vol.39 No.2
(1-3)-$\beta$-glucanase 동위효소의 발현 양상을 등 전점 전기영동 젤에서 직접 검출 확인할 수 있는 방법을 개발하였다. 개발된 방법은 시판되고 있는 (1-3)-$\beta$-glucanase활성 측정용 염료착색 기질을 이용하였다. 본 방법은 신속, 간편하며 보리 종자에서 발현되는 것으로 알려져 있는 모든 (1-3)-$\beta$glucanase 동위효소를 검출할 수 있을 정도로 민감하고 특이적이었다. 시판되고 있는 Penicillium(1-3)-$\beta$-glucanase에 대한 활성 검출 한계단위는 50 $\mu$U 정도로 추정되었다. 따라서, 본 방법은 특별한 시설이나 연구 인력을 확보하고 있지 않는 연구실에서 식물체의 (1-3)-$\beta$-glucanase발현에 대한 단백질 수준에서의 연구를 수행하는데 유용하게 이용될 수 있을 것으로 생각된다. A procedure for the direct detection of (1-3)-$\beta$-glucanase isozymes in electrophoresis gels was developed. The procedure employed the commercial preparation of AZCL-pachyman as a chromogenic substrate for (1-3)-$\beta$-glucanases. The procedure detected the three basic isozymes which have been known to be expressed in germinating barley kernels. A major acidic and a minor isozymes were also detected in germinating kernels. The procedure was proved to be fast, simple and sensitive enough to be used for the analysis of the expression of (1-3)-$\beta$-glucanase isozymes in plant tissues. The detection limit of the procedure for the commercial preparation of Penicillium (1-3)-$\beta$-glucanase was estimated to be as low as 50$\mu$U. The procedure could be used for the investigation of (1-3)-$\beta$-glucanases in laboratories facilitated with ordinary equipments and research personnel.
Kwon, Jihyun,Han, Hye Sook,Kim, Hee Kyung,Baek, Seung-Woo,Yang, Yaewon,Lee, Ki Hyeong,Son, Seung-Myoung,Kim, Won-Dong,Kim, Dae Hoon,Yun, Hyo Yung The Korean Gastric Cancer Association 2018 Journal of gastric cancer Vol.18 No.3
We report a rare case of long-term survival in a patient who received local therapy and salvage chemotherapy for recurrent metastases, along with a literature review. A 65-year-old male patient underwent subtotal gastrectomy for advanced gastric adenocarcinoma. Six months after gastrectomy, 2 metastatic intra-abdominal lymph node enlargements were detected, which were treated with radiotherapy. At 55 months after gastrectomy, an abdominal wall mass was detected, which was treated by surgical resection. The patient received 5-fluorouracil/leucovorin/irinotecan chemotherapy for 27 months before and after radiotherapy and docetaxel chemotherapy for 6 months after surgical resection of the abdominal wall metastasis. At the last visit, 7.8 years since the initial resection of the primary gastric cancer and 6.2 years since detection of the first metastases, the patient was disease-free and required no further chemotherapy. This case suggests that repeated local therapy offers potential for long-term survival in a carefully selected subset of patients with recurrent metastases.