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RISS 인기검색어
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- 저자 : Yubo Xiao (검색결과 2 건)
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Light-Chain Cardiac Amyloidosis: Cardiac Magnetic Resonance for Assessing Response to Chemotherapy
Guo Yubo,Li Xiao,Gao Yajuan,Shen Kaini,Lin Lu,Wang Jian,Cao Jian,Zhang Zhuoli,Wan Ke,Zhou Xi Yang,Chen Yucheng,Zhang Long Jiang,Li Jian,Wang Yining 대한영상의학회 2024 Korean Journal of Radiology Vol.25 No.5
Objective: Cardiac magnetic resonance (CMR) is a diagnostic tool that provides precise and reproducible information about cardiac structure, function, and tissue characterization, aiding in the monitoring of chemotherapy response in patients with lightchain cardiac amyloidosis (AL-CA). This study aimed to evaluate the feasibility of CMR in monitoring responses to chemotherapy in patients with AL-CA. Materials and Methods: In this prospective study, we enrolled 111 patients with AL-CA (50.5% male; median age, 54 [interquartile range, 49–63] years). Patients underwent longitudinal monitoring using biomarkers and CMR imaging. At followup after chemotherapy, patients were categorized into superior and inferior response groups based on their hematological and cardiac laboratory responses to chemotherapy. Changes in CMR findings across therapies and differences between response groups were analyzed. Results: Following chemotherapy (before vs. after), there were significant increases in myocardial T2 (43.6 ± 3.5 ms vs. 44.6 ± 4.1 ms; P = 0.008), recovery in right ventricular (RV) longitudinal strain (median of -9.6% vs. -11.7%; P = 0.031), and decrease in RV extracellular volume fraction (ECV) (median of 53.9% vs. 51.6%; P = 0.048). These changes were more pronounced in the superior-response group. Patients with superior cardiac laboratory response showed significantly greater reductions in RV ECV (-2.9% [interquartile range, -8.7%–1.1%] vs. 1.7% [-5.5%–7.1%]; P = 0.017) and left ventricular ECV (-2.0% [-6.0%–1.3%] vs. 2.0% [-3.0%–5.0%]; P = 0.01) compared with those with inferior response. Conclusion: Cardiac amyloid deposition can regress following chemotherapy in patients with AL-CA, particularly showing more prominent regression, possibly earlier, in the RV. CMR emerges as an effective tool for monitoring associated tissue characteristics and ventricular functional recovery in patients with AL-CA undergoing chemotherapy, thereby supporting its utility in treatment response assessment.
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Visual analysis of doctor-patient relationship problems based on R language(1995-2022)
Shengnan Pang,Ruo Si,Yurong Bao,Yubo Xiao 중앙대학교 영상콘텐츠융합연구소 2023 TechArt :Journal of Arts and Imaging Science Vol.10 No.3
This study used R language technology to study the trend of doctor-patient relationship research from 1995 to 2022, based on a collection of doctor-patient relationship literature in the Web of Science database. The analysis was conducted from the perspective of doctor-patient relationship-related literature statistical general trend, then from the perspective of researchers, high-yield countries or regions of the overall situation, high-frequency keywords and keyword clustering visualization, and after the visual atlas longitudinal analysis of the literature topic of evolution, finally through the analysis of the world’s first highly cited literature summary and verifying the direction of doctor-patient research. This study identified that, although doctor-patient research in China started late, the quality of the literature could be improved. China attaches great importance to cooperative research and plays a vital role in communication in doctor-patient research. Finally, countries worldwide believe that one of the core aspects of the doctor-patient relationship lies in the transmission and communication between doctors and patients.
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