Growth Mechanism and Electrochemical Properties of Porous Hollow Tin Oxide Nanospheres

Youwen Yang,Dongming Ma,Ting Cheng,Yuanhao Gao,Guanghai Li 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.6

"Porous hollow SnO2 nanospheres were prepared by means of enforced Sn2+ hydrolysis method under hydrochloric acid medium. These hollow nanospheres with an average diameter of 220 nm had a very thin shell thickness of about 40 nm and were surrounded by elongated octahedral-like nanoparticles with the apex oriented outside. The experimental conditions, such as HCl content, reaction temperature and time directly dominated the morphology, structure and crystallinity of the obtained samples. A pre-oxidation-nucleation-growth mechanism and inside-out Ostwald-ripening method was proposed on the basis of the previous research and time-dependent experiments. Electrochemical tests showed that the porous hollow SnO2 nanospheres exhibited improved cycling performance for anode materials of lithium-ion batteries, which retained a high reversible capacity of 540.0 mAhg-1 , and stable cyclic retention at 120th cycle."

Olaparib plus bevacizumab as a first-line maintenance treatment for patients with advanced ovarian cancer by molecular status: an updated PAOLA-1 based cost-effectiveness analysis

Youwen Zhu,Qiuping Yang,Kun Liu,Hui Cao,Hong Zhu 대한부인종양학회 2024 Journal of Gynecologic Oncology Vol.35 No.1

Objective: The PAOLA-1 trial (NCT02477644) reported final sur vival benefit associated witholaparib plus bevacizumab maintenance treatment of patients with advanced ovarian cancer(AOC) based on molecular status. Our aimed to compare the cost-effectiveness of olaparibplus bevacizumab for overall patients, patients with a breast cancer susceptibility genes(BRCA) mutation, homologous recombination deficiency (HRD), or HRD without BRCAmutations AOC from the context of the American healthcare system. Methods: Analysis of health outcomes in life-years (LYs), quality-adjusted life-years (QALYs),and the incremental cost-effectiveness ratio (ICER) in various molecular status-based AOCpatient at a $150,000/QALY of willingness-to-pay was performed using a state-transitionedMarkov model with a 20-year time horizon. Meanwhile, sensitivity analyses assessments werealso used to gauge the model’s stability. Results: The ICERs of olaparib plus bevacizumab versus bevacizumab alone were $487,428($374,758), $249,579 ($191,649), $258,859 ($198,739), and $270,736 ($206,640) per QALY(LY) in the overall patients, patients with BRCA mutations, patients with HRD, and patientswith HRD without BRCA mutations AOC, respectively, which indicated that The ICERs washigher than $150,000/QALY in the US. Progression-free sur vival (PFS) value and olaparib costemerged as the primar y influencing factors of these findings in the sensitivity analysis. Conclusion: At current cost levels, olaparib plus bevacizumab treatment is not a cost-effectivetreatment for patients with AOC regardless of their molecular status in the US. However, thismaintenance treatment may be more favorable health advantages for patients with BRACmutations AOC.

Code Analysis and Improvement of Onion Routing Anonymous Systems

Tianbo Lu,Youwen Wang,Lingling Zhao,Yang Lin,Xiaoyan Zhang 보안공학연구지원센터 2016 International Journal of Future Generation Communi Vol.9 No.8

With the development of Internet technology, network based activities such as e-commerce, internet voting and e-government, etc. have become increasingly frequent, People are increasingly concerned about the identity of network activity, content and other private information. In order to protect user privacy in network communications, governments, companies, universities and research institutes are pushing the research and development of the onion routing systems (TOR). Tor is the most popular anonymous communication system currently, which is based on technology of the second-generation onion routing. Tor has a low latency, encrypted data transmission, secure channel, etc., which are widely used in anonymous Web browsing, instant messaging, Secure Shell Client (SSH), etc. However, the development of the onion routing systems is constrained by complicated code factors. According to this situation, this paper put forward an overall architecture of TOR code, which contains Application Needs, Code Analysis and Improvement. This paper summarizes the overall framework of tor code structure, in order to make the code structure clearer, the whole code module is divided into several sub modules, using the function call diagram and UML diagram illustrates the main function of each module and call relation between each module. This paper gives code analysis for anonymous architecture of TOR. Finally, this paper put forward the improvement of routing algorithms of TOR. Based on this paper, a method has been created which is used to understand the tor code easily. Furthermore, systematic analysis of the tor code provided in this paper aims to research the working principle and promote the further development of the onion routing.

Nonlinear Increase of Spatial Noise for Ultrashort Pulses with Different Temporal Widths

Lifu Zhang,Xiquan Fu,Jianqin Deng,Hua Yang,Youwen Wang,Shuangchun Wen,Huiwen Xu,Jinggui Zhang,Jin Zhang,Dianyuan Fan 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.55 No.2

In this paper, the dynamic evolution of the spatial noise modulation of ultrashort laser pulses in carbon disulfide (CS2) is investigated experimentally, and different temporal widths of the stretched pulse are analyzed for spatial noise gain. The spatial noise evolution (i.e., small-scale self-focusing) of ultrashort laser pulses with different temporal widths as a function of the length of the CS2 has been observed. If the spectral bandwidth is invariant, the experimental results show that a stretched pulse with a broader temporal width can postpone the small-scale self-focusing of spatial noise for longer medium length with constant input power or for greater input power with the same medium length. In this paper, the dynamic evolution of the spatial noise modulation of ultrashort laser pulses in carbon disulfide (CS2) is investigated experimentally, and different temporal widths of the stretched pulse are analyzed for spatial noise gain. The spatial noise evolution (i.e., small-scale self-focusing) of ultrashort laser pulses with different temporal widths as a function of the length of the CS2 has been observed. If the spectral bandwidth is invariant, the experimental results show that a stretched pulse with a broader temporal width can postpone the small-scale self-focusing of spatial noise for longer medium length with constant input power or for greater input power with the same medium length.

Construction of magnetic nanochains to achieve magnetic energy coupling in scaffold

Cijun Shuai,Xuan Chen,Chongxian He,Guowen Qian,Yang Shuai,SHUPING PENG,Youwen Deng,Wenjing Yang 한국생체재료학회 2022 생체재료학회지 Vol.26 No.3

Background: Fe3O4 nanoparticles are highly desired for constructing endogenous magnetic microenvironment in scaffold to accelerate bone regeneration due to their superior magnetism. However, their random arrangement easily leads to mutual consumption of magnetic poles, thereby weakening the magnetic stimulation effect. Methods: In this study, magnetic nanochains are synthesized by magnetic-field-guided interface co-assembly of Fe3O4 nanoparticles. In detail, multiple Fe3O4 nanoparticles are aligned along the direction of magnetic force lines and are connected in series to form nanochain structures under an external magnetic field. Subsequently, the nanochain structures are covered and fixed by depositing a thin layer of silica (SiO2), and consequently forming linear magnetic nanochains (Fe3O4@SiO2). The Fe3O4@SiO2 nanochains are then incorporated into poly l-lactic acid (PLLA) scaffold prepared by selective laser sintering technology. Results: The results show that the Fe3O4@SiO2 nanochains with unique core–shell structure are successfully constructed. Meanwhile, the orderly assembly of nanoparticles in the Fe3O4@SiO2 nanochains enable to form magnetic energy coupling and obtain a highly magnetic micro-field. The in vitro tests indicate that the PLLA/Fe3O4@SiO2 scaffolds exhibit superior capacity in enhancing cell activity, improving osteogenesis-related gene expressions, and inducing cell mineralization compared with PLLA and PLLA/Fe3O4 scaffolds. Conclusion: In short, the Fe3O4@SiO2 nanochains endow scaffolds with good magnetism and cytocompatibility, which have great potential in accelerating bone repair