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      • KCI등재

        청바지제품 세분시장 내 가격-품질 평가집단 추출에 관한 연구 : 결합분석과 mixture model를 이용하여 Based on Conjoint analysis and mixture model

        곽영식,이진화 한국의류학회 2002 한국의류학회지 Vol.26 No.11

        The purpose of this study was to identify the consumers who use the level of price as the indicator of the product quality. In order to implement the purpose of this study, Jeans market had been segmented by the mixture regression model, and price response function was calibrated for each segment. Based on the types of price response function, segments were allocated into one of two groups the group using the level of price as the quality indicator or the group not using the level of price as that. Then, characteristics of both groups were compared in terms of product attributes and demographic variables. Data were collected from the sample of the 230 undergraduate and graduate students in Seoul. For the data analysis mixture regression model, conjoint analysis and t-test were used. As a result, jeans market was divided into 5 segments. Segment 1,2,3 were allocated into the group not using the level of price as the quality indicator while segment 4,5 were done into the other group. Significant differences existed between two groups in product atttibutes, not in demographic variables. Mixture model and conjoint analysis were proved to be an effective set of tools in market segmentation.

      • KCI등재

        정신분열병의 경과 중 발생하는 우울증

        곽경환,박두병,최태영,민경준,이영식,기백석,나철 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.3

        연구목적 : 정신분열병을 음성증상군과 양성증상군으로 나누어 두 군 사이에 우울증이 차이가 있는지를 조사하고 정신분열별의 증상과 우울증과의 연관과 정신분열병의 경과 중 보이는 우울증사의 특징에 대해서 알아보고자 하였다. 방 법 : 중앙대학병원에 입원한 총 31명(남자 13명, 여자 18명)의 정신분열병 환자를 대상으로 PANSS, BDI, HDRS와 Simpson Angus Scale을 시행하였다. 결 과 : 1) BDI 21점 이상을 기준으로 했을 때, 정신분열병의 경과 중 우울증이 발생한 환자는 총 18%였으며, 양성증상군과 음성증상군 간에 차이는 없었다. 2) 양성증상군과 음성증상군 간에 BDI, HDRS 그리고 PANSS-D 등의 점수의 차이는 없었다. 3) 주관척도인 BDI와 객관척도인 HDRS와 PANSS-D 사이의 연관은 없었다. 결 론 : 정신분열병의 우울증은 양성증상이나 음성증상의 한 부분으로 생각하기보다는 또 다른 영역으로 받아들여야 할 것으로 보인다. 임상적으로 정신분열병에서 우울증은 발생되는 비율의 정도를 고려할 대 다른 증상과 더불어 집중적인 관심이 필요하며 이와 함께 우울증으로 인한 결과와 예후의 심각성을 고려할 때 우울증에 대한 인식 및 진단과 치료에 더 많은 진전이 있어야 한다. Objective : The heterogeneity of symptomatology within the group of schizophrenias is still a major obstacle for defining clinically useful subgroups of these disorders. One of these symptoms is depression. Recently there is a growing evidence suggesting that depressive symptoms and related mood disturbances are important in treating schizophrenia. This so because of the improvement of such side effects as extraphramidal symptoms with increasing use of atypical antipsychotics. Althought depression is known to be a serious problems of many schizophrenic patients, the nature and course of depression in schizophrenia remain unknown. Methods : The author examined the depressive features in 31 patients with schizophrenia. Rating on the PANSS, BDI and HDRS were obtained. Eighteen percent of the total patients had BDI score above 21, considered depressed. Results : There were no difference in BDI, hDRS and PANSS-D between positive symptoms group and negative synptom group. There was also no correlation between subject scale(BDI) and objective scales(HDRS, PANSS-D). Conclusions : Depression in schizophrenia needs intensive studies. It is also considered as another hereogeneous domain beside negative or positive symptom domain. Out of respect for the high prevalence and serious outcome of depression in schizophrenia, a more differentiated assessment, analysis, and treatment of depressive symptom is recommended.

      • KCI등재후보

        주정 중독 흰쥐에서 총담관 결찰이 간 및 혈청의 Glyoxalase I 활성에 미치는 영향

        곽춘식,김여희,변용준 啓明大學校 醫科大學 1995 계명의대학술지 Vol.14 No.4

        The activities of the rat liver and serum glyoxalase-I(GLO-I) were studied in cholestasis induced by common bile duct(CBD) ligation after chronic ethanol intoxication, and in cholestasis before acute ethanol intoxication to establish the biochemical background of alcohol hazards in hepatobiliary disease. GLO-I activities in the rat's liver and serum showed less increases when CBD was ligated after chronic ethanol intoxication than that in the CBD ligation alone. GLO-I activities in the rat's liver and serum showed no more increases when acute ethanol intoxication was induced after CBD ligation than that in the CBD ligation alone. On the other hand, when CBD was ligated after chronic ethanol intoxication, the value of Vmax of the liver GLO-I decreased significantly than that in the CBD was ligated alone. However, the values of Km of the liver GLO-I did not changes in the all experimental groups. Viewed from above results, when chronic ethanol intoxication is combined with cholestasis, GLO-I in the liver seems to be decrease its activity than that in cholestasis, and the cause of the decrease is thought to be decreased biosynthesis.

      • Retinol Palmitate로 유발된 선천성 기형

        김선,김수일,곽명순,박경란,이영호,김원식 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.1

        Vitamin A is known to have anticarcinogenic effects, inhibitory effect on growth and regeneration of bones and cartilages, antimutagenic effects, and teratogenic effect. For the study on the teratogenic effects of vitamin A, in this experiment, the retinol palmitate(Sigma Chemicals) in corn oil was administered orally to the pregnant rats (Sprague -Dawley, B.W.250±20gm) on the gestation day(GD) 8.5, 9.5, 10.5,11.5, and 12.5. Under ether anesthesia, the rats were sacrificed at the GD 17.5, laparotomized, hysterectomized after counting the number of pregnant sacs & absorbed fetuses. Within the saline, the pregnant sacs opened and the fetuses removed, under observation of fetal motility. The number of live fetuses was counted, weighed, and we observed the external anomaly under stereoscopy. To detect cleft palate, the mandible and the tongue were removed at their attached site. In this study, the pregnant sacs, absorbed fetuses, and fetal body weight of control and each experimental group were compared, and various congenital anomalies induced by retinol palmitate were obtained. The results were as follows: 1. There was no significant differences in the number of pregnant sacs between the control and the experimental groups. 2. The rate of fetal resorption was higher significantly in the GD 8.5 groups, but not in the other groups. 3. The fetal body weight was significantly lowered in the GD 8.5 and GD 11.5 groups, but not in the other groups. 4. The congenital anomalies induced by retinol palmitate were exencephaly, hydrocephalus, anophthalmia, cleft palate & digit anomaly, but not noted in GD 12.5 groups. 5. The kinds of congenital anomalies were as follows ; exencephaly and hydrocephalus in the GD 8.5 and GD 9.5 groups, cleft palates in the GD 9.5 and GD 10.5 groups, and the digit anomalies in the GD 11.5 group. On the basis of above results, the experimental teratological studies about the various chemicals which cause environmental contamination are considered to be possible, and should be studied forth.

      • 만성 활동성 간염에 있어서 Ursodeoxycholic acid의 치료효과

        김성록,안병철,윤영미,탁원영,곽규식,최용환,정준모 慶北大學校 醫科大學 1991 慶北醫大誌 Vol.32 No.4

        The purpose of this study is to evaluate the clinical and biochemical effects of SGD-F^(R)(UDCA, Vitamin B_1, Vitamin B_2 complex) in chronic active hepatitis. Observed cases were given orally after each meal(three times a day) for 4 weeks. The results were as follows: 1. Among subjective symptoms, improvement rate showed in easy fatigability 86.7%, anorexia 68.0%, indigestion 80.0%, nausea and vomiting 72.7%, RUQ pain 83.3%. 2. Biochemical parameters such as SGOT, SGPT, showed to be improved significantly after the 4 weeks treatment.(p<0.01) 3. There was no specific side effect during the study period in all cases. In conclusion, SGD-F^(R) capsule may be safe and effective for chronic active hepatitis.

      • KCI등재

        Development of the Online Activity Index of K-pop Fans

        Young-Sik Kwak(곽영식),Jae-Won Hong(홍재원),Yoon-Jung Nam(남윤정),Kang-Il Han(한강일),Mi-Hee Kim(김미희),Byeong-Min Na(나병민),Xue Wang,He-Feng Song 한국컴퓨터정보학회 2021 韓國컴퓨터情報學會論文誌 Vol.26 No.9

        본 연구는 K-pop 팬들의 온라인 활동 내용과 활동의 정도를 실증적으로 측정하는 것을 목적으로 한다. 연구목적 달성을 위해 먼저 K-pop 아티스트에 대한 팬 애착도에 영향을 주는 주요 온라인 활동들을 탐색하였으며, 나아가 해당 온라인 활동들의 상대적 중요성을 도출하였다. 이를 통해 궁극적으로 K-pop팬 온라인 활동지수(KOAI: K-pop fans’ Online Activity Index)를 개발하였고 개별 응답자들의 KOAI를 실증적으로 측정하였다. 연구결과 K-pop 팬 온라인 활동지수(KOAI)는 팬클럽 가입 여부, V live+ 유료시청 여부, 아티스트 관련 VOD 시청 여부, 팬클럽에 글을 쓰는 정도, 아티스트의 가치를 높이기 위해 관련 유튜브를 보는 정도 등 K-pop 팬들의 다섯 가지 온라인 활동으로 구성됨을 알 수 있었다. 본 연구는 K-pop 마케터로 하여금 팬 반응을 얻기 위한 다양한 온라인 활동에 마케팅 자원을 보다 효율적이고 효과적으로 배분할 수 있는 기준을 제공함으로써 마케팅 성과를 높이게 하였다는 데 실무적 의의가 있다. 또한 K-pop 팬들의 온라인 행동을 이해하기 위한 학문적 지식 축적에 기여가 있다. This study aims to empirically measure K-pop fans" content and the extent of online activities. To achieve the purpose of the study, the researchers identify the statistically significant online activities that determine the intensity of fan attachment toward K-pop artists. Further, the research confirms the relative importance of various meaningful online activities. Consequently, we can develop the K-pop Online Activity Index (KOAI) model and apply it to this index model empirically for each respondent. We found that the model consists of five online activities of K-pop fans: whether joining the fan club or not, whether paying per view V live+ or not, whether watching VODs associated with artists or not, the degree of fan club writing, the degree of watching a lot on YouTube to improve the value of my artists. This study has practical significance in that it allows K-pop marketers to improve their marketing performance by providing content that will enable them to more efficiently and effectively allocate marketing resources to various online activities to get fan responses. It allows accumulating academic knowledge to understand the behavior in the field of online behavior for K-pop fans.

      • KCI등재
      • KCI등재

        Development and Roll-Out of A Coronavirus Disease 2019 Clinical Pathway for Standardized Qualified Care in Public Hospitals in Korea

        Kwak Mi Young,Jo Eun Young,Chin Bum Sik,Park Se Eun,Yim Jun,Lee Jung Eun,Jo Kyung Eun,Kim Yeon-Sook,Lee Jeong Eun,Yoon Young Kyung,Seo Yu Bin,Jeong Su Jin,Kang Yu Min,Joo Eun-Jeong,Yoon Jong Hyun,Kim 대한감염학회 2022 Infection and Chemotherapy Vol.54 No.2

        Despite the coronavirus disease 2019 (COVID-19) vaccination roll-out, variant-related outbreaks have occurred repeatedly in Korea. Although public hospitals played a major role in COVID-19 patients’ care, difficulty incorporating evolving COVID-19 treatment guidelines called for a clinical pathway (CP). Eighteen public hospitals volunteered, and a professional review board was created. CPs were formulated containing inclusion/exclusion criteria, application flow charts, and standardized order sets. After CP roll-out, key parameters improved, such as increased patient/staff five-point satisfaction scores (0.41/0.57) and decreased hospital stays (1.78 days)/medical expenses (17.5%). The CPs were updated consistently after roll-out as new therapeutics drugs were introduced and quarantine policies changed.

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