중첩증후군:만성 폐쇄성 폐질환을 가 진 폐쇄성 수면무호흡-저호흡 증후군

최영미,Choi, Young-Mi 대한수면의학회 2008 수면·정신생리 Vol.15 No.2

Overlap syndrome can be defined as a coexistence of chronic obstructive pulmonary disease (COPD) and sleep apnea-hypopnea syndrome (SAHS). The association of COPD and SAHS has been suspected because of the frequency of both diseases. Prevalence of COPD and SAHS is respectively 10 and 5% of the adult population over 40 years of age. However, a recent study has shown that the prevalence of SAHS is not higher in COPD than in the general population. The coexistence of the two diseases is only due to chance. SAHS does not affect the pathophysiology of COPD and vice versa. Prevalence of overlap syndrome is expected to occur in about 0.5% of the adult population over 40 years of age. Patients with overlap syndrome have a more profound hypoxemia, hypercapnia, and pulmonary hypertension when compared with patients with SAHS alone or usual COPD patients without SAHS. To treat the overlap syndrome, nocturnal noninvasive ventilation (NIV) or nasal continuous positive airway pressure (nCPAP) can be applied with or without nocturnal oxygen supplement.

BCG 접종후 발생한 결핵성 농양 및 골수염 1례

최영미,강현호,조병수,차성호,임성직,이주희,Choi, Young Mi,Kang, Hyeon Ho,Cho, Byung Soo,Cha, Sung Ho,Lim, Sung Jic,Lee, Ju-Hee 대한소아감염학회 1998 Pediatric Infection and Vaccine Vol.5 No.1

BCG osteomyelitis is rare comlication and the incidence rate has been estimated to be 1/milion vaccinated neonate and infants. BCG osteomyelitis is also reported as a complication of intravesical BCG treatment for bladder carcinoma. We had experienced a 14 months old infant who presented swelling, tenderness and redness on left upper arm suspicious due to BCG vaccination. The MRI finding showed $2{\times}4{\times}4cm$ subcutaneous abscess with cortical defect on proximal humerus and axillary lymph adenopathy. The histologic finding showed diffuse caseous necrosis and Langhans type giant cell. We report A case of BCG osteomyelitis.

폐쇄성 수면 무호흡 증후군과 상기도 저항 증후군의 진단적 및 임상적 차이

최영미,Choi, Young-Mi 대한수면의학회 2011 수면·정신생리 Vol.18 No.2

It has been controversial whether upper airway resistance syndrome (UARS) is a distinct syndrome or not since it was reported in 1993. The International Classification of Sleep Disorders classified UARS under obstructive sleep apnea syndrome (OSAS) in 2005. UARS can be diagnosed when the apnea-hypopnea index (AHI) is fewer than 5 events per hour, the simultaneously calculated respiratory disturbance index (RDI) is more than 5 events per hour due to abnormal non-apneic non-hypopneic respiratory events accompanying respiratory effort related arousals (RERAs), and oxygen saturation is greater than 92% at termination of an abnormal breathing event. Although esophageal pressure measurement remains the gold standard for detecting subtle breathing abnormality other than hypopnea and apnea, nasal pressure transducer has been most commonly used. RERAs include phase A2 of cyclical alternating patterns (CAPs) associated with EEG changes. Symptoms of OSAS can overlap with UARS, but chronic insomnia tends to be more common in UARS than in OSAS and clinical symptoms similar with functional somatic syndrome are also more common in UARS. In this journal, diagnostic and clinical differences between UARS and OSAS are reviewed.

폐쇄성 수면 무호흡 증후군과 폐동맥 고혈압에서 엔도텔린-1의 역할

최영미,Choi, Young-Mi 대한수면의학회 2010 수면·정신생리 Vol.17 No.2

Obstructive sleep apnea syndrome is associated with significant cardiovascular morbidity and increased mortality. However, it was controversial whether obstructive sleep apnea syndrome could cause pulmonary hypertension. The controversy was resolved by several studies that have shown pulmonary hypertension in 20% to 40% of patients with obstructive sleep apnea syndrome without underlying other cardiopulmonary diseases and reductions in pulmonary arterial pressure in patients with obstructive sleep apnea syndrome after treatment with nocturnal continuous positive airway pressure. Recent studies provide strong evidence for endothelial dysfunction in obstructive sleep apnea syndrome and pulmonary hypertension. Endothelin-1 is a 21 amino acid peptide with diverse biologic activity such as highly potent vasoconstrictor and mitogen regulator that may play a key role in obstructive sleep ap-nea syndrome and pulmonary hypertension. Continuous positive airway pressure therapy is moderately effective in reducing pulmonary arterial pressure. Further researches are needed to assess the therapeutic efficacy of pharmacologic therapy with agents that inhibit the action of endothelin-1 in obstructive sleep apnea syndrome patients with pulmonary hypertension.

인프라그램을 활용한 "식물의 건강 모니터링" STEAM 수업이 초등학생의 창의적 문제해결력, 과학 탐구 능력 및 정의적 영역에 미치는 영향

최영미 ( Young Mi Choi ),김덕호 ( Deok Ho Kim ),양지혜 ( Ji Hye Yang ),홍승호 ( Seung Ho Hong ) 韓國生物敎育學會 2016 생물교육 Vol.44 No.1

Digital technology has adopted in classroom for meaningful and relevant learning. In this paper, the development and application of the STEAM program, whose main theme is ‘Monitoring of plants health’, are introduced. The STEAM program also contained a series of activities to use Infragram, an online based infrared camera tool. This study focused on the effects of the program on creative problem solving ability, scientific process skills and affective domain in elementary student’s level. The study subjects were composed of two groups of fifth grade students in J province. The experimental group was involved to learn in the integrated education program class, while the comparative group participated in traditional science lessons. As the result, the developed STEAM program contributed to the significant improvement of elementary students’ creative problem solving ability, scientific process skills and affective domain. The authors propose that STEAM program for plants health monitoring using Infragram is a powerful approach to facilitate learners’ development of these skills.

<여씨향약언해> 화산본의 성조 연구- <석보상절>, <월인천강지곡>의 성조와 비교를 중심으로-

최영미 ( Young Mi Choi ) 한말연구학회 2012 한말연구 Vol.- No.30

The purpose of this study has two aims. The one is to describe similarities and differences between the tone in <Seokbosangjeo>, <Worincheongangjigok> published in mid-15th century and it in <Yeossihyangakonhae> published in 16th century early, And the other to elucidate a change of the tonal system from mid-15th century to 16th century early, According to the study, the tone in <Yeossihyangyakonhae> inherit it in <Seokbosangjeo> and <Worincheongangjigok>. But there is a slight change of the tonal system in the 16th century early. The tonal system consists of three tones in the mid-15th century:pyeongcheuk patterns, departing tonal pattern and rising tonal pattern. The pyeongcheuk patterns in the mid-15th century are classified into two tones:the pyeonggeohyeong and the pyeongsanghyeong by the distinction between departing tone and rising tone behind plain tone. But the pyeongsanghyeong in the pyeongcheuk patterns has been seriously undermined, since the process to distinguish between departing tone and rising tone behind plain tone nearly disappeared in the 16th century early. So the pyeongsanghyeong in the tonal system may be confused by the process of disappearance. Therefore, there was no loss of the tone as well as the destruction of the tonal system in the 16th century early. However, there is a slight change of the tonal system due to the change of constraints on combination of the tonemes.

본문회고전략 중재가 읽기장애아동의 독해력에 미치는 효과

최영미 ( Young-mi Choi ),김자경 ( Ja-kyoung Kim ) 대구대학교 한국특수교육문제연구소 2009 특수교육저널 : 이론과 실천 Vol.10 No.3

The purpose of this study was to examine the effects of training in text lookback strategy on reading comprehension of children with reading disabilities. The subjects of the study were 4th and 5th grade children with reading disabilities at different elementary schools. A total of 20 children participated in the study. The pretest-posttest control group design was employed for the study by organizing an experimental group and a control group with each of 10 children. No signigicant differences are found in the IQ and reading comprehension scores between groups. The experimental group participated in a 15-session text lookback training and each session run for 40 minutes. As the result, children in the experimental group showed a significant improvement on their responses about text explicit, text implicit, and script implicit questions. Therefore the text lookback strategy was effective on teaching reading comprehension for children with reading disabilities. Implications about strategy instruction for children with reading disabilities and suggestions for the future study were discussed.

성인남자의 신체충실지수에 따른 체형 연구 - 대구 , 경북 지역의 성인남자 신체계측치를 중심으로 -

최영미(Young Mi Choi),김계선(Kyee Seon Kim),홍정민(Jung Min Hong) 대구가톨릭대학교 자연과학연구소 1995 응용과학연구논집 Vol.4 No.-

초압 복귀시간 측정을 통한 MK 507과 Timolol 의 방수 생성 억제 효과의 비교

최영미(Young Mi Choi),오중협(Jung Hyub Oh) 대한안과학회 1996 대한안과학회지 Vol.37 No.5

영월 방언의 거성형과 성조 변화

최영미(Choi Young-mi) 한글학회 2020 한글 Vol.- No.327

이 연구는 영월 방언 체언의 성조를 분석하고 약 30년이라는 시간차를 두고 거성형의 성조 실형을 비교하여 영월 방언 성조 변화를 설명하고자 했다. 그 결과, 영월 방언의 성조체계는 두 가지 성조 변화가 진행중임을 확인할 수 있었다. 하나는 성조체계 내에 영향을 주지 않는 단순한 음성 변화이고 다른 하나는 성조형 분포의 변화로 말미암아 성조체계 내에 재구조화가 일어나는 변화이다. 먼저, 단순한 음성 변화는 평복형과 상성형의 음조 변화이다. 최명옥(1999)의 자료에서는 평복형과 상성형의 음조는 어절의 둘째음절과 셋째음절에 어절에서 가장 높은 고조 [H]가 실현되었다. 그러나 30년 후인 현재 자료에서는 평복형과 상성형의 음조는 어절 끝에서 둘째음절에 어절에서 가장 높은 고조 [H]가 실현되었다. 다음, 영월 방언 성조체계 내에 재구조화를 촉발하는 성조형 분포의 변화이다. 30년 전 자료에서는 거성형이 분포의 제약 없이 안정적인 성조 실현을 보인다. 하지만, 현재 필자의 자료에서는 거성형이 매우 불안정한 성조 실현을 보인다. 즉, 영월 방언 거성형은 3음절 이상 어절에서 평2형(□□, □□ · □)에 합류해서 거성형이 존재하지 않고, ‘·말(斗)/M/[Mˉ ]’과 같이 1음절 단독형과 ‘·춤·이/M²/[HH]’처럼 2음절 어절에서도 첫소리가 강자음으로 시작하는 단어에서만 실현된다. 결국, 성조형 분포의 변화로 인해서 2음절 어절에서 거성형은 A유형(·춤·이/M²/[HH]), B유형(·풀·이/M²/[HH]~풀이/H²/[MH]), C유형(물이/H²/[MH]) 등이 공존한다. This study described the tone of substantive words and the tone changes of the departing pitch pattern in the Yeongwol dialect. In this study, two states of pitch patterns in the same region were studied over a more than 30-year interval. The results of this study indicate that the tonal system of the Yeongwol dialect has undergone two tone changes. One is a phonetic change that does not impact the tonal system. The other is a phonological change that is still in progress that is caused by the change in the distribution of X. These changes can be summarized as follows. First, the phonetic changes are the results of the pitch changes in the plain and rising pitch patterns. Thirty years ago, the highest peak was placed on the second syllable in a word, but now the highest pitch appears on the second-to-last syllable in a word. Second, the distribution of the departing pitch pattern that triggers the reconstruction in the tonal system of the Yeongwol dialect has changed. Thirty years ago, the departing pitch pattern was stable, but it has since become significantly unstable in the tonal system of the Yeongwol dialect. There are two main reasons why the tone of the departing pitch pattern has undergone some noticeable changes. One is that, in words of more than three syllables, the departing pitch pattern merges into the plain pitch pattern, resulting in no departing pitch pattern in the Yeongwol dialect tone patterns. The other is that the departing pitch patterns are realized in a limited way, even in the context of two-syllable words. There are three types of departing pitch patterns. Type A is realized as [HH], I would write this in A, B, C order depending on the speaker. Only type A is realized in words whose initial sounds start with strong consonants like /k<SUP>h</SUP>,t<SUP>h</SUP>,p<SUP>h</SUP>,tʃ<SUP>h</SUP>/. Therefore, it is likely that departing pitch patterns will gradually disappear from the tonal system, mainly due to their instability.