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Jung-Pil Suh,Tae-Hwan Noh,Ki-Young Kim,Jeong-Ju Kim,Yeon-Gyu Kim,Kshirod K. Jena 한국작물학회 2009 Journal of crop science and biotechnology Vol.12 No.3
Bacterial blight, caused by Xanthomonas oryzae pv. oryzae (Xoo) is a destructive disease of rice in the major rice growing countries of Asia. In 2003, a serious bacterial blight epidemic occurred in the southwestern coastal areas in Korea, causing significant yield loss due to the emergence of a new race, K3a. IR24 near-isogenic lines containing Xa4, xa5, Xa7 and Xa21 genes conferred different degrees of resistance to the most virulent K3a isolate, HB01009 in an inoculation experiment in the greenhouse. Expression levels of the resistance genes, Xa4, xa5 and Xa21 were studied in two F2 populations derived from the crosses between elite japonica cultivars and an advanced backcross breeding line possessing Xa4, xa5 and Xa21 genes. F2 progenies segregated for K3a resistance (R) and susceptible (S) phenotypes in a ratio of 3(R):1(S) indicated that K3a resistance was controlled by a major dominant gene. Three PCR markers tightly linked to the resistance genes Xa4, xa5 and Xa21 confirmed the presence of the genes and their interaction with each gene. This study demonstrated that the Xa21 gene dominantly contributed to K3a resistance. However, the Xa4 gene also contributed to the full expression of resistance. The level of expression of strong resistance to K3a race was attributed to the presence of Xa21 and Xa4 genes irrespective of the presence of xa5 gene. Our results suggest that the R-gene combinations of Xa4+Xa21 could be a useful and effective strategy toward improving resistance to K3a race of Korean japonica cultivars. Bacterial blight, caused by Xanthomonas oryzae pv. oryzae (Xoo) is a destructive disease of rice in the major rice growing countries of Asia. In 2003, a serious bacterial blight epidemic occurred in the southwestern coastal areas in Korea, causing significant yield loss due to the emergence of a new race, K3a. IR24 near-isogenic lines containing Xa4, xa5, Xa7 and Xa21 genes conferred different degrees of resistance to the most virulent K3a isolate, HB01009 in an inoculation experiment in the greenhouse. Expression levels of the resistance genes, Xa4, xa5 and Xa21 were studied in two F2 populations derived from the crosses between elite japonica cultivars and an advanced backcross breeding line possessing Xa4, xa5 and Xa21 genes. F2 progenies segregated for K3a resistance (R) and susceptible (S) phenotypes in a ratio of 3(R):1(S) indicated that K3a resistance was controlled by a major dominant gene. Three PCR markers tightly linked to the resistance genes Xa4, xa5 and Xa21 confirmed the presence of the genes and their interaction with each gene. This study demonstrated that the Xa21 gene dominantly contributed to K3a resistance. However, the Xa4 gene also contributed to the full expression of resistance. The level of expression of strong resistance to K3a race was attributed to the presence of Xa21 and Xa4 genes irrespective of the presence of xa5 gene. Our results suggest that the R-gene combinations of Xa4+Xa21 could be a useful and effective strategy toward improving resistance to K3a race of Korean japonica cultivars.
Kang, Eun-Young,Jee, Sung Ju,Kim, Cuk-Seong,Suh, Kwang-Sun,Wong, Alex W.K.,Moon, Jae Young Elsevier 2018 Journal of critical care Vol.44 No.-
<P><B>Abstract</B></P> <P><B>Purpose</B></P> <P>Early cognitive assessment in the intensive care unit (ICU) is essential to monitor cognitive dysfunction after critical illness. We have implemented a Computer Cognitive Senior Assessment System–Screen (CoSAS–S) which is a brief, objective, and tablet-based cognitive screening test as a mobile platform to detect any cognitive problems in ICUs. This study aimed to evaluate the feasibility and initial validation of a tablet-based CoSAS–S in critically ill patients with sepsis.</P> <P><B>Materials and methods</B></P> <P>Thirty-six eligible patients completed CoSAS–S, Mini-Mental State Examination–Korean Version (MMSE–K) and Korean Version of Montreal Cognitive Assessment (K-MoCA) for validity testing at the ICU.</P> <P><B>Results</B></P> <P>Eighty-eight percent of programmed assessments were completed by the sample. Spearman correlations of the CoSAS–S with MMSE–K (rho=0.613–0.874, p<0.00) and K–MoCA scores (rho=0.666–0.897, p<0.001) were moderate to high. Intra-class correlation coefficient (ICC) of total CoSAS–S score between two raters was 0.93 (p<0.001; 95% CI=0.82–0.97), suggesting the inter-rater reliability of CoSAS-S was excellent.</P> <P><B>Conclusions</B></P> <P>Support was found for the feasibility and validity of CoSAS-S. The application of CoSAS-S could identify the cognitive functioning of the patients. Utility of CoSAS-S in other clinical populations should be tested.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Cognitive Senior Assessment System–Screen (CoSAS–S) is a mobile flat-form, tablet-based cognitive screening test. </LI> <LI> This study supports the feasibility and validity of tablet-based cognitive screening, ‘CoSAS-S’ in patients with sepsis. </LI> <LI> CoSAS-S could identify the critically ill patients without cognitive dysfunction in the ICUs. </LI> <LI> Utility of CoSAS-S in other clinical settings should be studied in the future study. </LI> </UL> </P>
High-Pressure Synthesis of $SmFeAsO_{1-x}F_x$(x=0.2) Single Crystals
이현숙,박재현,이재엽,김주영,조병기,정창욱,이후종,Lee, Hyun-Sook,Park, Jae-Hyun,Lee, Jae-Yeap,Kim, Ju-Young,Cho, B.K.,Jung, Chang-Uk,Lee, Hu-Jong The Korean Superconductivity Society 2009 Progress in superconductivity Vol.10 No.2
Fluorine-doped $SmFeAsO_{1-x}F_x$ single crystals with the nominal value of x=0.2 were grown at $1350-1450^{\circ}C$ under the pressure of 3.3 GPa by using the self-flux method. Plate-shaped single crystals in the range of a few-150 ${\mu}m$ in their lateral size were obtained. The detailed crystal structure was analyzed by using the x-ray diffractometry. Superconducting transition temperature, determined by the resistive transition, of a single crystal was about 49 K with a narrow resistive transition width of ${\sim}1$ K. A relatively sharp transition, a low residual resistivity, and a large residual resistivity ratio compared with those reported for $REFeAsO_{1-x}F_x$(RE=Sm, Nd) single crystals indicate the high quality of our single crystals.
김영권 ; 이찬주 ; 민재기 ; 최영학 김천대학교 1992 김천대학교 논문집 Vol.13 No.-
In September 1989, a 32 year old man visited the eye clinic of the Shilla Hospital, Kon Kuk University at Chung Ju, complaining of foreign body sensation and itching ca-used by an actively moving worm in his right eye. He was a farmer and lived near Chung Ju, chungbug conjunctival congstion was fo-und in the right eye, but the findings of other physical examinations were normal. Two thread like moving worms were removed from his eye and examined of their morphology They were observed microscopically after alchol-glycerin clearing. One was male which was slender, 9.6ra in length and had a coiled tail. The other was female of 8.1mm in length with a vaginal pore anterior to the esopha-gointestinal junction. The ovary or uterus was full will lots of unembryonated or c-mbryonated eggs. Its tail was round but the cuticle was intact. The anal pore was not distinctive. The number of transverse cuticular striations was 120-280per mm. These worms compatible with the descriptions of Thelazia callipaeda except for the tail of the female worm. The female worm looked with the anomalous tail., This is the 20th case record of thelaziasis in Korea.
New 7-Hydroxycoumarin-Based Fluorescent Chemosensors for Zn(II) and Cd(II)
Swamy, K.M.K.,Kim, Min-Jung,Jeon, Hye-Ryeong,Jung, Ji-Young,Yoon, Ju-Young Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.12
Five new 4- or 8-substituted-7-hydroxycoumarin derivatives (1-5) were synthesized as fluorescent sensors for metal ions. Fluorescent changes and selectivity for metal ions were compared based on the introduction of different ligands and/or testing with different substitution positions of 7-hydroxycoumarin in aqueous solution. Especially, probes 2, 3 and 5 displayed large fluorescence enhancements with $Zn^{2+}$ and $Cd^{2+}$. Probes 2 and 3 showed moderate selectivity for $Zn^{2+}$ over $Cd^{2+}$. On the other hand, probe 4 showed large fluorescence quenching effects upon the addition of $Ag^+$ and $Hg^{2+}$.
Sanjeewa, K.K. Asanka,Jayawardena, Thilina U.,Kim, Hyun-Soo,Kim, Seo-Young,Ahn, Ginnae,Kim, Hak-Ju,Fu, Xiaoting,Jee, Youngheun,Jeon, You-Jin The Korean Society of Fisheries and Aquatic Scienc 2019 Fisheries and Aquatic Sciences Vol.22 No.2
Background: This study is aimed at identifying the anti-inflammatory properties of 70% ethanol extract produced from an edible brown seaweed Sargassum horneri (SJB-SHE) with industrial-scale production by Seojin Biotech Co. Ltd. S. horneri is a rich source of nutrient and abundantly growing along the shores of Jeju, South Korea. Methods: Here, we investigated the effect of SJB-SHE on LPS-activated RAW 264.7 macrophages. The cytotoxicity and NO production of SJB-SHE were evaluated using MTT and Griess assays, respectively. Additionally, protein expression and gene expression levels were quantified using ELISA, Western blots, and RT-qPCR. Results: Our results indicated that pre-treatment of RAW 264.7 macrophages with SJB-SHE significantly inhibited LPS-induced NO and $PGE_2$ production. SJB-SHE downregulated the proteins and genes expression of LPS-induced iNOS and COX2. Additionally, SJB-SHE downregulated LPS-induced production of pro-inflammatory cytokines (tumor necrosis factor-${\alpha}$, interleukin (IL)-6, and IL-$1{\beta}$). Furthermore, SJB-SHE inhibited nuclear factor kappa-B (NF-${\kappa}B$) activation and translocation to the nucleus. SJB-SHE also suppressed the phosphorylation of mitogen-activated protein kinases (ERK1/2 and JNK). Conclusions: Collectively, our results demonstrated that SJB-SHE has a potential anti-inflammatory property to use as a functional food ingredient in the future.