후두 및 하인두 편평세포암종에서 E-cadherin의 면역조직화학적 발현

도남용,나한조,이도용,허준,최지윤,이홍영,임성철 조선대학교 2000 The Medical Journal of Chosun University Vol.25 No.2

Background and Objectives : The cell-cell adhesion molecule E-cadherin is necessary for the maintenance of the epithelial cellular structure. We were designed to confirm the significance of E-cadherin as a marker for differentiation and invasiveness of squamous cell carcinoma of the larynx and hypopharynx. Materials and Methods : Our study was investigated for the immunohistochemical expression of the epithelium-specific cell adhesion molecule E-cadherin in formalin fixed paraffin embedded tissue specimen of 32 cases of squamous cell carcinoma of larynx and hypopharynx. Results : The positive expression of E-cadherin was 56.3%(18 cases) in squamous cell carcinoma of the larynx and hypopharynx. Decreased E-cadherin expression was a stastistically significant correlation with a increased grade of lymph node stage and clinical stage. Reduced expression was seen in the large tumor size and poorly differentiated tumors, but these result was not statistically significant. Conclusion : The expression of E-cadherin may be related with progression of squamous cell carcinoma of the larynx and hypopharynx. But these correlation were not sufficient for the prognostic indicators in squamous cell carcinomas of the larynx and hypopharynx.

자궁경부의 선암종에서 Polymerase Chain Reaction에 의한 Human Papillomavirus DNA 16/18의 검색

이상숙,박남조,윤종국 대한병리학회 1995 Journal of Pathology and Translational Medicine Vol.29 No.4

초등학교 교육과정과 교과서에 농업·농촌의 기능 및 가치 반영 방안

서우석,강대구,정남용,김재호,이윤조 한국농업교육학회 2006 농업교육과 인적자원개발 Vol.38 No.4

이 연구는 농업ㆍ농촌의 기능과 가치를 재정립하고 이를 초등학교 교육과정 및 교과서에 반영시킬 수 있는 방안을 제시하는데 그 목적이 있었다. 이를 위하여 먼저 선행연구 고찰을 통하여 농업ㆍ농촌의 기능과 가치를 재개념화하고, 이를 토대로 내용 분석 틀을 개발하여 초등학교 교육과정 및 교과서를 분석 하고, 그 결과를 토대로 교육과정 및 교과서에 반영시키기 위한 방안을 제시하였다. 그 주요 결과는 다음과 같다. 첫째, 농업ㆍ농촌의 기능과 가치는 크게 자연환경적 기능(수자원 함양 기능, 환경정화 기능, 생태계 보전기능, 자연재해 방지 기능), 사회문화적 기능(전통문화 보전 기능, 정서의 순화 기능, 자연학습의장 제공 기능), 사회경제적 기능(농산물 공급 기능, 직업 기회 제공 기능, 국토의 균형발전 기능, 타 산업에의 기여 기능)으로 분류하였다. 둘째, 농업ㆍ농촌의 기능과 가치를 바탕으로 초등학교 교육과정 및 교과서를 분석한 결과, 전 학년에 걸쳐서 자연학습의 장 제공 기능과 전통문화 보전 기능이 높게 나타났고, 그 다음으로는 농산물 공급기능과 정서순화기능이 높게 나타났다. 반면에 수자원함양기능과 환경정화기능은 상대적으로 낮게 나타났다. 셋째, 내용분석을 토대로 교과의 성격을 고려하여 각 교과별로 농업ㆍ농촌의 기능과 가치를 반영시킬 수 있는 방안을 제시하였다. 마지막으로, 각 교과별로 농업ㆍ농촌의 기능과 가치 반영 방안을 체계적으로 이행하기 위한 행ㆍ재정적 지원 방안을 교육과정 개발 측면, 교과서 개발 측면, 교육과정 운영측면, 정책적 지원 측면으로 구분 하여 제시하였다. The purpose of the study is to suggest the strategies for incorporating the roles and values of agriculture & rural areas as a part of the national curriculum and elementary school textbooks. For this purpose, this study was conducted as follows; First, we reclassified the roles and values of agriculture & rural areas after critically reviewing literature: environmental conservation functions, socio-cultural functions and socio-economic functions. Second, based on the new classification, we develop a framework for analyzing the national curriculum and elementary school textbooks. The functions of rural areas as places for learning about nature and purifying emotion and the importance of agriculture in providing agricultural product were frequently presented but the functions of sustaining water resources and environmental purification were relatively less presented in the national curriculum and elementary school textbooks. Third, we suggested strategies for incorporating the roles and values of agriculture & rural areas in the national curriculum and elementary school textbook based on the analysis. Finally, we suggested necessary administrative and financial assistance to systematically and effectively implement the suggested strategies for developing a new curriculum and textbooks as well as implementing the curriculum.

The Effect of Extraction Conditions and Film Side on the Molecular Conformation of Silk Sericin Film

( Yoon Nam Jo ),( Do Gyu Bae ),( In Chul Um ) 한국잠사학회 2013 International Journal of Industrial Entomology Vol.26 No.2

In this study, silk sericin films were prepared using different extraction methods, and the molecular conformation of sericin was examined using Fourier-transform infrared spectroscopy with attenuated total reflection geometry. Additionally, the effect of the film side (air-facing side or plate-facing side) on the molecular conformation of the sericin films was investigated. Interestingly, the molecular conformation of the sericin film depended on the film side. The molecular conformation of air-facing side of the sericin film was significantly influenced by extraction solution and time. The b-sheet crystallization and the crystallinity index of the sericin film markedly increased with an increase in the extraction time in hot water. The order of the crystallinity indices for the sericin films obtained with different extraction solutions was as follows: citric acid solution > urea solution >> hot water. In contrast, no remarkable differences were observed in the molecular conformation of the plate-facing side of the sericin film after extraction in hot water for different time periods. Urea and citric acid solution extractions showed remarkably higher crystallinity indices for sericin than those obtained after hot water extraction. However, no significant differences were observed in the crystallinity index of sericin between urea and citric acid solution extraction in plate-facing side of the film.

The Effect of Extraction Conditions and Film Side on the Molecular Conformation of Silk Sericin Film

Jo, Yoon Nam,Bae, Do Gyu,Um, In Chul Korean Society of Sericultural Science 2013 International Journal of Industrial Entomology Vol.26 No.2

In this study, silk sericin films were prepared using different extraction methods, and the molecular conformation of sericin was examined using Fourier-transform infrared spectroscopy with attenuated total reflection geometry. Additionally, the effect of the film side (air-facing side or plate-facing side) on the molecular conformation of the sericin films was investigated. Interestingly, the molecular conformation of the sericin film depended on the film side. The molecular conformation of air-facing side of the sericin film was significantly influenced by extraction solution and time. The ${\beta}$-sheet crystallization and the crystallinity index of the sericin film markedly increased with an increase in the extraction time in hot water. The order of the crystallinity indices for the sericin films obtained with different extraction solutions was as follows: citric acid solution > urea solution >> hot water. In contrast, no remarkable differences were observed in the molecular conformation of the plate-facing side of the sericin film after extraction in hot water for different time periods. Urea and citric acid solution extractions showed remarkably higher crystallinity indices for sericin than those obtained after hot water extraction. However, no significant differences were observed in the crystallinity index of sericin between urea and citric acid solution extraction in plate-facing side of the film.

Effect of the Extract of Herbal Drugs Mixture on Brain Function in Rats

Yoon Jo Oh,Ah-ram Lee,Jin-Joo Hue,Yea Eun Lee,Lan Li,Jung-Su Lee,Min-hang Cho,Sang Yoon Nam,Young Won Yun,Byungwoo Ahn,Jae-Hwang Jeong,Sang-Hwa Lee,Beom Jun Lee 한국실험동물학회 2006 Laboratory Animal Research Vol.22 No.4

Green tea, Crataegus oxycantha fruit, gingko leaves and tangleweed were known to increase blood circulation and improve brain function. The mixture containing green tea (50 g), Crataegus oxycantha fruit (50 g), gingko leaves (20 g), and tangleweed (20 g) was water-extracted and freeze-dried to powder. The pharmacological effect of the extract of herbal drugs on acetylcholinesterase (AChE) in an in vitro enzyme system and in rats was investigated. The extract of herbal drugs at the doses of 10, 25, 50 and 100 ㎍/㎖ decreased activity of AChE by 8.8, 22.1, 43.1 and 63.0%, respectively. The treatment of the extract of herbal drugs at the dose of 0.1 g/㎏ b.w. to rats for 5 and 10 consecutive days reduced AChE activity in the brain by 12.8 and 26.9 %, respectively, corresponding to increases by 26.4 and 59.7% in the concentration of acetylcholine (ACh) in the brain of rats, compared with the control rats. The levels of ATP in the brain also increased in treatment group in a time-dependent manner. The liver toxicity was not shown as determined by serum biochemistry. These results suggest that a composition of these herbal drugs may improve brain function by increasing the levels of acetylcholine and ATP.

Structural characteristics and properties of silk sericin solution and film prepared using different solvent

Yoon Nam Jo,Do Gyu Bae,In Chul Um 한국응용곤충학회 2013 한국응용곤충학회 학술대회논문집 Vol.2013 No.10

In this study, silk sericin solutions and films were prepared with different solvents: formic acid and water. Also, silk sericin film from aqueous solution was prepared at different casting temperature. Regardless of solvent type, silk sericin solutions showed a shear thinning implying highly molecular entangled state of silk sericin. Silk sericin aqueous solution showed a higher turbidity than that of formic acid solution. Silk sericin aqueous solution showed shorter gelation time than formic acid. FTIR results showed β-sheet crystallization of silk sericin was affected by casting solvent and temperature. Silk sericin film from aqueous solution showed more β-sheet conformation as the casting temperature was decreased. Silk sericin film from formic acid showed higher crystallinity index than silk sericin films cast from aqueous solution. XRD diffraction measurement showed similar results to those of FTIR. In case of mechanical properties, tensile strength of sericin film from formic acid was higher than sericin films from aqueous solution.

Genetic Stock Identification of Common Carp (Cyprinus carpio) by Detection of Intraspecific DNA Sequence Variation in the Mitochondrial 12S rRNA Gene

남윤권(Yoon Kwon Nam),주수동(Su Dong Chu),정창화(Chang Hwa Jeong),노충환(Choong Hwan Noh),조재윤(Jae-Yoon Jo),김동수(Dong Soo Kim) 한국수산과학회 양식분과 1997 韓國養殖學會誌 Vol.10 No.4

잉어(Cyprinus carpio)와 붕어(Carassius auratus)간 잡종의 세포유전학적 분석

남윤권(Yoon Kwon Nam),오승용(Sung-Yong Oh),조재윤(Jae-Yoon Jo),김동수(Dong Soo Kim) 한국수산과학회 양식분과 1998 韓國養殖學會誌 Vol.11 No.1

Activation 메커니즘 기반의 RMI API 설계 및 구현

조희남(Hee-Nam Jo),윤기현(Gi-Hyun Yoon),정명조(Myoung-Jo Jung),이철훈(Cheol-Hoon Lee) 한국정보과학회 2002 한국정보과학회 학술발표논문집 Vol.29 No.2Ⅱ

객체 지향 분산 시스템에서 어느 한 객체가 메모리를 차지하게 되면 그 객체를 Active 하다고 하며 그 반대를 Passive 하다고 말한다. Activation 이란 Passive 한 객체를 Active 하게 해주는 전환 과정을 뜻한다. 자바의 RMI(Remote Method Invocation)는 Activation 메커니즘을 JDK1.2.x 버전부터 채택해 사용하고 있는데, Activation 메커니즘이 지원되지 않는 JDK1.1X의 RMI에 Activation 메커니즘을 덧붙이는 형태로 API를 제공하고 있기 때문에 그 뼈대는 Activation 메커니즘 기반이 아니므로 그 효율성 및 성능이 떨어진다 볼 수 있다. 본 논문은 이를 개선 Activation 메커니즘 기반의 API를 설계 구현한다.