Thick Tetrahedral Amorphous Carbon Films Prepared by Filtered Catholic Vacuum Arc Method

Yongqing Shen,Han Zhou,Xu Zhang 한국표면공학회 2017 한국표면공학회 학술발표회 초록집 Vol.2017 No.11

Comparative analysis of liver transcriptome reveals adaptive responses to hypoxia environmental condition in Tibetan chicken

Yongqing Cao,Tao Zeng,Wei Han,Xueying Ma,Tiantian Gu,Li Chen,Yong Tian,Wenwu Xu,Jianmei Yin,Guohui Li,Lizhi Lu,Shuangbao Gun Asian Australasian Association of Animal Productio 2024 Animal Bioscience Vol.37 No.1

Objective: Tibetan chickens, which have unique adaptations to extreme high-altitude environments, exhibit phenotypic and physiological characteristics that are distinct from those of lowland chickens. However, the mechanisms underlying hypoxic adaptation in the liver of chickens remain unknown. Methods: RNA-sequencing (RNA-Seq) technology was used to assess the differentially expressed genes (DEGs) involved in hypoxia adaptation in highland chickens (native Tibetan chicken [HT]) and lowland chickens (Langshan chicken [LS], Beijing You chicken [BJ], Qingyuan Partridge chicken [QY], and Chahua chicken [CH]). Results: A total of 352 co-DEGs were specifically screened between HT and four native lowland chicken breeds. Gene ontology and Kyoto encyclopedia of genes and genomes enrichment analyses indicated that these co-DEGs were widely involved in lipid metabolism processes, such as the peroxisome proliferator-activated receptors (PPAR) signaling pathway, fatty acid degradation, fatty acid metabolism and fatty acid biosynthesis. To further determine the relationship from the 352 co-DEGs, protein-protein interaction network was carried out and identified eight genes (ACSL1, CPT1A, ACOX1, PPARC1A, SCD, ACSBG2, ACACA, and FASN) as the potential regulating genes that are responsible for the altitude difference between the HT and other four lowland chicken breeds. Conclusion: This study provides novel insights into the molecular mechanisms regulating hypoxia adaptation via lipid metabolism in Tibetan chickens and other highland animals.

Incentive Mechanism based on Game Theory in Kad Network

왕서(Xu Wang),니영청(YongQing Ni),양대헌(DaeHun Nyang) 한국정보보호학회 2010 정보보호학회논문지 Vol.20 No.3

Kad 네트워크는 파일 공유 시스템 중 가장 널리 알려진 네트워크이다. 파일 공유 시스템은 사용자의 일방적 파일 다운로드 받기, 가짜파일 업로드하기, 바이러스 배포하기 등에 사용 되는 등의 문제를 가지고 있고, 이러한 문제점을 극복하기 위하여, 이 논문에서는 게임 이론을 바탕으로 하는 인센티브 메커니즘을 제안한다. 이 메커니즘은 Kad 사용자를 위하여 보다 안정적이고 효율적인 네트워크 환경을 만들어 준다. 즉, 쓸모 없고 위험한 파일 등을 제공하는 다른 사용자들이 처벌받는 것에 반하여, 가치 있는 리소스를 공유한 사용자는 신용이 증가하는 대가를 받는다. Kad 네트워크에서 이 인센티브 메커니즘은 사용자의 악의적인 행동을 찾거나 방지하고 사용자들 사이에서의 정직한 통신을 장려하는데 도움을 준다. The Kad network is a peer-to-peer (P2P) network which implements the Kademlia P2P overlay protocol. Nowadays, the Kad network has attracted wide concern as a popular architecture for file sharing systems. Meanwhile, many problems have been coming out in these file sharing systems such as freeriding of users, uploading fake files, spreading viruses, and so on. In order to overcome these problems, we propose an incentive mechanism based on game theory, it establishes a more stable and efficient network environment for Kad users. Users who share valuable resources receive rewards by increasing their credits, while others who supply useless or harmful files are punished. This incentive mechanism in Kad network can be used to detect and prevent malicious behaviors of users and encourage honest interaction among users.

Application of the Multi-Source Data Fusion Algorithm in the Hail Identification

Yonghua Zhu,Yongqing Wang,Zhiqun Hu,Fansen Xu,Renqiang Liu 한국기상학회 2022 Asia-Pacific Journal of Atmospheric Sciences Vol.58 No.3

In this study, the canonical correlation analysis algorithm (CCA) is used to fuse the two-dimensional wind field retrieved from the single-Doppler weather radar, the three-dimensional wind field retrieved from the dual-Doppler weather radars, the observations from the ground automatic weather stations and the meteorological reanalysis data in three hail episodes (“0625” episode in Beijing, “0330” and “0801” episodes in Guangdong). During the hail episode in Beijing on June 25, 2020, an evident and long-lasting three-body scatter spike was observed, which played an important role in the hail identification and warning. In the three-dimensional wind field retrieved from the dual-Doppler weather radars, there is horizontal convergence of northeasterly and northwesterly winds and that of northwesterly and southeasterly winds in the low-level strong echo area, and there are obvious updrafts in the vertical wind field structure. Such a circulation configuration is favorable for the development and maintenance of hail storm. The multi-source data fusion of the wind fields can effectively improve the identification of the low-level convergence. The data fusion for the other two hail episodes (“0330” and “0801” episodes in Guangdong) yields the same conclusion. It is revealed that the dual-radar fusion performs better than the single-radar fusion in the identification of the meso-γ scale vortices. It can visually illustrate the characteristics of the cyclonic convergent flow fields which is more consistent with the near-surface observation. It can be concluded that the multi-source data fusion technique is practicable in the three severe convection processes.

Cyclic CO2 capture characteristics of a pellet derived from sol-gel CaO powder with Ca12Al14O33 support

Cong Luo,Ying Zheng,Yongqing Xu,Haoran Ding,Chuguang Zheng,Changlei Qin,Bo Feng 한국화학공학회 2015 Korean Journal of Chemical Engineering Vol.32 No.5

A novel calcium-based pellet was prepared by extrusion of sol-gel CaO powder and cement with high aluminum- based content. Limestone was used for comparison. The cyclic CO2 capture performance and carbonation kinetics of the sorbents were investigated in a thermogravimetric analyzer (TGA). The changes in phase and microstructure were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and Brunauer Emmet Teller (BET) surface area, respectively. The results indicate that the pellet consisted of CaO and Ca12Al14O33 after initial calcination. Limestone reactivity decreased dramatically with the increase in the cycle number, whereas the pellet showed a relatively stable cyclic CO2 capture performance with high reactivity. The CO2 capture capacity of the pellet achieved 0.43 g CO2/g sorbent after 50 cycles at 650 oC and 850 oC for carbonation and calcination, respectively. Moreover, the pellet obtained fast carbonation rates with slight decay after multiple cycles. The porous microstructure of the pellet contributed to the high reactivity of the sorbent during high temperature reactions, and the support material of Ca12Al14O33, enhanced the cyclic durability of the calcium-based sorbents.

Performance of Homologous and Heterologous Prime-Boost Immunization Regimens of Recombinant Adenovirus and Modified Vaccinia Virus Ankara Expressing an Ag85B-TB10.4 Fusion Protein against Mycobacterium tuberculosis

( Yiming Kou ),( Mingming Wan ),( Wei Shi ),( Jie Liu ),( Zhilei Zhao ),( Yongqing Xu ),( Wei Wei ),( Bo Sun ),( Feng Gao ),( Linjun Cai ),( Chunlai Jiang ) 한국미생물생명공학회(구 한국산업미생물학회) 2018 Journal of microbiology and biotechnology Vol.28 No.6

Tuberculosis (TB) remains a serious health issue around the word. Adenovirus (Ad)-based vaccine and modified vaccinia virus Ankara (MVA)-based vaccine have emerged as two of the most promising immunization candidates over the past few years. However, the performance of the homologous and heterologous prime-boost immunization regimens of these two viral vector-based vaccines remains unclear. In the present study, we constructed recombinant Ad and MVA expressing an Ag85B-TB10.4 fusion protein (AdH4 and MVAH4) and evaluated the impact of their different immunization regimens on the humoral and cellular immune responses. We found that the viral vector-based vaccines could generate significantly higher levels of antigen-specific antibodies, IFN-γ-producing splenocytes, CD69⁺CD8⁺ T cells, and IFN-γ secretion when compared with bacillus Calmette-Guerin (BCG) in a mouse model. AdH4-containing immunization regimens (AdH4-AdH4, AdH4-MVAH4, and MVAH4-AdH4) induced significantly stronger antibody responses, much more IFN-γ-producing splenocytes and CD69⁺CD8⁺ T cells, and higher levels of IFN-γ secretion when compared with the MVAH4-MVAH4 immunization regimen. The number of IFN-γ-producing splenocytes sensitive to CD8⁺ T-cell restricted peptides of Ag85B (9-1p and 9-2p) and Th1-related cytokines (IFN-γ and TNF-α) in the AdH4-MVAH4 heterologous prime-boost regimen immunization group was significantly higher than that in the other viral vector-based vaccine- and BCG-immunized groups, respectively. These results indicate that an immunization regimen involving AdH4 may have a higher capacity to induce humoral and cellular immune responses against TB in mice than that by regimens containing BCG or MVAH4 alone, and the AdH4-MVAH4 prime-boost regimen may generate an ideal protective effect.