알칼리 處理가 폴리에스테르 纖維의 構造에 미치는 影響

趙龍錫,金完守 대구효성가톨릭대학교 1987 연구논문집 Vol.34 No.1

Polyethylene terephthalate(PET) fibers which were drawn at the temperature of 80℃ with draw ratios of 1.5, 2.0, 2.5 and 3.0 at the rate of 1%/sec were treated with 30% aquous solution of NaOH at 40℃ for 1hr. Experimental studies on the surface photograph, weight loss, birefringence, and thermal shrinkage of PET fibers have carried out. Results form these studies are as follows: 1. In the treatment of alkali, pit shapes of fibers were altered from a round shape to a longish oval with increasing draw ratio. 2. There was a linear relationship between the weight loss and specific surface area of PET fiber. 3. The birefringence of treated PET fibers generally became hower than that of untreated. 4. The thermal shrinkage of treated PET fibers was less than that of untreated.

중국에서 이식한 종어 (Leiocassis longirostris Gunther)의 외부 형태 및 초기생활사

이완옥,김경환,김대희,조용철,김응오 한국어류학회 2004 韓國魚類學會誌 Vol.16 No.1

한국에서 절멸된 것으로 알려진 종어 (Leiocassis longifostris)를 국내에 복원하고, 양식대상종으로 개발하기 위하여 중국에서 도입하여 외부형태를 비교하고, 난발생 과정 및 부화자어의 형태를 연구하였다. 도입된 표본의 계수·계측형질을 국내와 중국에 알려진 문헌과 비교한 결과 큰 차이를 보이지 않았다. 중국에서 도입한 암수 한쌍의 성어에서 채란하였고, 습식법으로 수정하였다. 수정란의 크기는 2.01∼2.10 mm(n=10)이었으며, 알의 형태는 원반형이고, 난막은 무색투명하였으며, 강한 접착력이 있었다. 난황은 담황색이고 유구는 없었다. 수정 1시간 후에 배반이 완성되었고, 1시간 30분 후에 난할이 시작되었다. 수정란의 수온을 21.5∼23.0℃로 유지할 때 30∼50분 간격으로 이후 난할이 계속되었다. 수정 후 상실기는 6시간에 도달하였고, 낭배기는 20시간 20분 후에 완성되었다. 난황 표면에서 관찰되는 특이한 연동운동은 상실기에 시작되어 포배기 말기인 30% epiboly기까지 계속되었다. 수정 75시간 후에 부화에 이르렀고, 부화 직후 자어의 크기는 전장 5.91∼6.10 mm 이었다. 부화 3일 후에 입이 열리고, 수염과 부레가 완성되었으며, 전장 9.07 ∼9.37 mm까지 자랐다. 부화 15일후에는 모든 지느러미가 완성되어 후기자어기 상태이었고, 전장 14.80∼16.50 mm로 자랐으며, 부화 25일 후에는 체형, 체색 그리고 생활습성 등이 성체와 유사하고, 전장은 18.59∼22.35 mm까지 성장하였다. The Long-snout bullhead, Leiocassis longirostris, is an introduced fish from China which had become extinct in Korea. Its morphological characteristics and early life history was studied to obtain useful information required for restoration of the species and also for its utilization as an aquaculture fish. Measurements and counts of specimens introduced into Korea were included in the range of those taken from the known literature of Korea and China. Eggs were obtained by fertilization by wet method in the laboratory using one mature male and female adults of introduced L. longirostris. The fertilized eggs measured 2.01-2.10 ㎜ (n = 10) in diameter. The eggs were diskshaped and strongly adhesive, with colorless transparent membrane. The yolk was pale yellow in color with no oil globule. The blastodisc was formed in about 1 hour and cleavage started around 1 hour 30 minutes after fertilization. The cleavage intervals were about 30-50 minutes at 21.5-23℃. The morula stage was reached at 6 hours, and gastrulation was completed at 20 hours 20 min. after fertilization. Peristalsic movements of the yolk surface started at the morula stage and continued to the blastula stage (30% epiboly). Hatching occurred 75 hours after fertilization, and newly hatched larvae were 5.91-6.10 ㎜ (n = 10) in total length (TL). The mouth was open, and barbels and the air-bladder were completely formed 3 days after hatching, at 9.07-9.37 ㎜ TL. All the fin rays were completely formed and the larvae became a postlarva 15 days after hatching at 14.80-16.50 ㎜ in TL. Body shape, color pattern, and habitat behavior were similar to those in the adult at 25 days after hatching and a size of 18.59-22.35 ㎜ TL.

코자 정(로자탄 칼륨 50mg)에 대한 로자르탄 정의 생물학적 동등성

김용원,박완수,김성수,서지형,조성희,이헌우,류재환,이경태 한국약제학회 2006 Journal of Pharmaceutical Investigation Vol.36 No.2

共同住宅 中央 集中 煖房設備의 信賴度에 관한 硏究

김동완,정순성,조용수 동아대학교 건설기술연구소 1997 硏究報告 Vol.21 No.1

The purpose of this study is to obtain reliability of heating equipments in apartment building. Field data concerning the failure of heating equipments recorded at the apartments constructed 14 years ago are used. As a result of the field data analysis, failure time distribution and cumulative hazard function of boiler, heat exchanger, steam header and various pumps are expressed in Weibull probability graph. The scale and shape parameters, MTBF of each equipments are presented by regression line of Weibull probability graph. Presented parameter wi31 be come into use a reference data to evaluate the reliability, to plan the maintenance scheme, and to evaluate economic renewal of equipments.

6개 원소로 이루어진 짝이중결합화합물과 R_2AsCI와의 반응

주완철,이용암,유응철 성균관대학교 기초과학연구소 1986 論文集 Vol.37 No.2

From the reactions of orthohydroxy-6-membered conjugated system, benzil-mono-orthohydroxyanil, with Me_2AsCl and chloro [Toluene-(2, 3)-dithiolato(2)] arsenic (Ⅲ), reaction products was isolated. From the IR and NMR-spectroscopic analysis for these reaction products, it is confirmed that reaction products are charge-transfer complexes of As. From these results, we found that the chemical behaviour of trivalent As is not analogous to trivalent P.

共同住宅 中央 集中 煖房設備의 信賴度에 관한 硏究

김동완,정순성,조용수 東亞大學校 建設技術硏究所 1997 硏究論文集 Vol.21 No.1

The purpose of this study is to obtain reliability of heating equipment’s in apartment building. Field data concerning the failure of heating equipment’s recorded at the apartments constructed 14 years ago are used. As a result of the field data analysis, failure time distribution and cumulative hazard function of boiler, heat exchanger, steam header and various pumps are expressed in Weibull probability graph. The scale and shape parameters, MTBF of each equipment’s are presented by regression line of Weibull probability graph. Presented parameter will be come into use a reference data to evaluate the reliability, to plan the maintenance scheme, and to evaluate economic renewal of equipment’s.

토양에서 분리한 Bacillus sp. G1으로부터 혈전 용해 효소의 순수 분리 및 그 유전자 크로닝

갈상완,조용운,김홍출,이상원,권득남 진주산업대학교 1998 산업과학기술연구소보 Vol.- No.5

토양으로부터 새로운 혈전 용해효소 생성 미생물을 순수 분리하였으며, 그 미생물의 특성을 조사하여 Bacillus종으로 확인하였다. 이 미생물로부터 혈전 용해 효소를 cthanol precipitation, DEAE-Sephadex G-50 column 그리고 Sephadex G-75 gel filteration column chromatography를 통하여 순수 분리하였다. 이 enzyme은 핏덩어리를 분해시키는데 고도로 특이적이며, 직접 분해시키는 type이었다. 이 효소의 분자 무게는 28 kDa 정도였으며, N-terminal amino acid sequence는 Gln-Thr-Gly-Gly-Ser-Ile-Ile-Asp-Pro-Ile-Asn-Gly-Tyr-Asn-Ser-Gly-Ile-Thy-Gln-Ala였다. 이 효소를 암호화하는 유전자를 위 미생물의 chromo-some으로부터 short-gun방법에 의해 크로닝하였으며 현지 DNA 연결순서 결정 중이다. 여러 가지 알려진 혈전 용해 효소와의 N-terminal amino acid 연결 순서 비교에서 이 효소는 Bacillus가 생성하는 새로운 혈전 용해 효소임을 확인하였다. A Bacillus sp. strain producing a new fibrinolutic enzyme was isolated from soil. The fibrinolytic enzyme was purified to electrophoretic homogeneity through consecutive procedures including ethanol precipitation, DEAE-sephadex A-50 column and Sephadex G-75 gel filtration column. The enzyme was highly specific forward fibrin clots and their direct degarder. The molecular weight of the enzyme was 28 kDa and the first 20 amino acids of the N-terminal sequence were Gln-Thr-Gly-Gly-Ser-Ile-Ile-Asp-Pro-Ile-Asn-Gly-Tyr-Asn-Ser-Gly-Ile-Thy-Gln-Ala. The gene encoding the fibrinolytic enzyme was cloned from chromosomal DNA of the bacillus sp. GI by the shot gun method. In comparison of the N-terminal amino acid sequence with those of several fibrinolytic enzymes the GK is a novel fibrinolytic enzyme of Bacillus sp. strain.

농촌지역 중학생들의 체력과 정신건강에 관한 연구

장봉우,김태완,조경욱,김용인 忠北大學校 平生體育硏究所 1997 平生體育硏究所 論文集 Vol.9 No.-

This study was performed to investigate the relationship between the physical fitness and mental health state of the rural middle school students. Two-hundred thirty-four middle school students were placed into two gender groups(boys and girls) and/or three age groups(14, 15, and 16 yrs). All subjects completed the physical fitness tests and the mental health questionnaire. After those tests, the data was collected and analyzed by MANOVA and ANOVA, and Pearson's correlation and multiple regression. The conclusions were as follows. First, in consequence of the physical fitness comparison by gender and age, while aging, boys did not show a significant difference in power, balance, ability, and flexibility, having significant improvements in muscle strength, muscular endurance, and cardiovascular endurance. Second, in consequence of the analysis of mental health state by gender, results showed that boys were better than girls in the mental health state, especially boys were better in Somatization, Anxiety, Photic Anxiety, and Psychotism. Third, in consequence of the analysis of mental health status by age, results showed a significant difference in Obsession and Interpersonal Sensitivity among nine symptom check-up lists. The older the students were, the more they were suffering from Obession, and Interpersonal Sensitivity. Finally, in consequence of the analysis of the relationship between physical fitness and mental health status by gender, the physical fitness factors of boy students had no meaningful relationship with mental health factors. On the other hand, girl students had a meaningful relationship between muscle strength and mental health factors-Anxiety, Interpersonal Sensitivity, Hostility, Phobic Anxiety, Paranoid Adaption, and Psycotism. Also girl students had a significant relationship between flexibility and mental health factors-Obsessive, Somatization, Depression, Hostility, Phobic Anxiety, Paranoid Ideation and Psychotism.

부산지역 사무소 건물의 연면적에 따른 냉방설비 시스템의 라이프 사이클 코스트 분석

정순성,김동완,조용수 동아대학교 건설기술연구소 1997 硏究報告 Vol.21 No.1

This study is aimed at proposing an economic Cooling System by total area using Life Cycle Costing, a general economical efficiency analysis method considering total amount of investment, service life, salvage value and the change of price caused by interest rate or inflation. LCC elements of Cooling System are Initial costs, Operations costs, Maintenance costs, Replacement/Alteration costs, Tax costs, Salvage costs etc., and considerable factors are Discount or Interrest rate, Escalation, Service life etc. In order to compare design alternatives, both present and future costs for each alternative must be brought to a common point in time. Costs may be converted to today's cost by the present-worth method, or may be converted to an annual series of payments by the annualized method.

요로감염증 환자의 치료에서 메로페넴(Meropenem)과 이미페넴/실라스타틴(Imipenem/Cilastatin)의 임상효과 및 안정성

김세웅,이승주,이지열,조용현,신완식,윤문수 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.1

목적 :메로페넴은 실라스타틴을 복합투여하지 않아도 되는 새로운 계열의 카바페넴계 항생물질이다. 요로감염 치료에 있어서의 메로페넴의 효과와 안전성을 평가하기 위하여 기존의 카바페넴계 항생물질인 이미페넴/실라스타틴과 동시에 비교임상실험을 실시하였다. 방법 : 본 임상시험은 전향적, 무작위 방법을 통하여 시행하였다. 1996년 10월부터 1998년 2월까지 가톨릭대학교 의과대학 부속 성모병원 및 울산대학교 외과대학 부속 중앙병원 비뇨기과에 입원한 신우신염과 복잡성방광염 환자 115명을 대상으로 하였고, 연속적 무작위 배정방법을 통하여 메로페spa군 58명과 이미페넴/실라스타틴군 57명으로 분류하였다. 두가지 약제는 모두 0.5 g을 12시간 간격으로 정맥주사 하였고, 평균 투약기간은 4일 (3-8일) 이었다. 임상효과, 세균학적 평가 및 부작용을 비교 관찰하였다. 결과 : 총 67명의 환자가 시험을 완료하여 평가가 가능하였고, 이 중 메로페넴군은 34명이었고, 이미페넴/실라스타틴군은 33명이었다. 증상의 치료 및 개선을 임상적 유효성이 있는 경우로 하였을 때, 메로페넴투여군은 34례중 32례 (94.1%)에서, 이미페넴/실라스타틴투여군은 33례중 29례 (87.9%)에서 유효율을 보였다. 세균학적 평가에서 메로페넴 투여군은 34례중 32례 (94.1%)에서, 이미페spa/실라스타틴투여군은 33례중 29례 (87.9%)에서 세균학적 소실율을 보였다. 세균학적 재발 은 각각 4명과 7명이 나타났고, 재감염은 메로페넴군은 나타나지 않았지만, 이미페넴/실라스타틴군은 2명이 나타났다. 임상효과와 세균학적 평가에서는 두 약제간의 통계학적 차이는 없었다. 부작용은 메로페spa투여군 56례중 1례 (1.8%)에서, 이미페넴/실라스타틴투여군 53례중 1례 (1.9%)에서 나타났으며, 임상검사치 이상은 메로페넴투여군 45례중 10례 (22.2%)에서, 이미페넴 실라스타틴투여군 44례중 8례 (18.2%)에서 나타났으나 전체적으로 특별히 문제가 된 증례는 없었다. 결론 :결론적으로 메로페spa은 신우신염 및 복잡성방광염과 같은 요로감염에 대하여 이미페넴/실라스타틴과 동등한 효과를 나타내는 유용한 약제라고 생각된다. Background : Metopenem is the first of a new class carbapenems which may be administered without cilastatin. The clinical study was carried out to assess efficacy and safety of metopenem in the treatment of urinary tract infections, in comparison to imipenem/cilastatin. Methods : This was a controlled, two-center, prospective, randomized study with two parallel groups. From October 1996 until February 1998, a total of 115 consecutive patients with urinary tract infections, such as pyeolonephritis and complicated cystitis, were randomly allocated into two groups, 58 in the meropenem group and 57 in the imipenem/cilastatin group. Both drugs were administered intravenously, at a dose of 0.5 g every 12 hours. The mean duration of therapy was 4 days (3-8 days) for both treatment. Clinical and bacteriological reponses were assessed at the begining of treatment, during treatment, at the end of treatment, and follow-up (1-2 weeks). Results : A total of 67 patients, 34 of meropenem and 33 of imipenem/cilastatin, were evaluable for response. Overall, a positive clinical response (recovery and improvement) was observed in 32 (94.1%) of 34 patients treated with meropenem and in 29 (87.9%) of 33 patients with imipenem/cilastin and the corresponding eradication rates of the primary pathogens were 32 (94.1%) of 34 patients and 29 (87.9%) of 33 patients, respectively. The microbiological relapse after the treatment completion was recorded in 4 patients treated with meropenem and 7 patients given imipenem/cilastath and superinfections occurred in none and 2 patients, respectively. No statistically significant differences in the clinical or bacteriological outcome were observed between the treatment groups. Both drugs were well tolerated with adverse events considered to be related to therapy being recorded for 1 (1.8%) of 56 patients treated with meropenem and 1 (1.9%) of 53 of those who had been given imipenenjcilastatin. Conclusion : Empirial monotherapy with meropenem was therefore as effective and as well tolerated as that with imipenem/cilastatin for the treatment of urinary tract infections.