http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Yihan Pan (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Fatty acid-binding protein 5 activates cyclooxygenase-2 and promotes hypoxic injury in LO2 cells
Pan Long,Pang Yihan,Xiao Heng,Deng Xin,Chen Qingsong 대한독성 유전단백체 학회 2022 Molecular & cellular toxicology Vol.18 No.1
Background Hepatic hypoxia always results in liver inflammation and dysfunction. Fatty acid-binding protein 5 (FABP5) has been reported as a hypoxia-inducible gene and a regulator of inflammatory reaction . Objective To evaluate the effects of FABP5 on hypoxic liver injury and its potential mechanisms. Results FABP5 was hypoxia-inducible expression in liver tissues and LO2 cells. The expression levels of IL6 and TNFα were upregulated with the increasing expression of FABP5 in LO2 cells. Downregulation of FABP5 expression decreased the expression levels of ALT, AST and increased cell viability of hypoxic LO2 cells. Downregulation of FABP5 expression inhibited the cyclooxygenase-2/prostaglandin E2 (COX-2/PGE2) pathway and decreased inflammatory reaction in hypoxic LO2 cells. Conclusions FABP5 was shown to activate COX-2/PGE2 pathway and promote hypoxic injury in LO2 cells. FABP5 may be a potential target for the treatment of hypoxic liver injury.
-
Zhendong Wang,Yihan Pan,Yi Lu,Xihui Zhou Council on Tall Building and Urban Habitat Korea 2023 International journal of high-rise buildings Vol.12 No.1
Under the dual pressure of population growth and land shortage, threedimensional development is the inevitable choice for cities in China. In such a scenario, a mixed-use complex has considerable potential in its realization and research. Based on space syntax and the three-dimensional visibility graph analysis, this paper describes the spatial and functional layout of the Shanghai Super Brand Mall and studies the relationship between spatial visibility and user behaviour through linear regression analysis and correlation analysis. This paper studies three different types of user behaviour, namely, path selection, staying selection, and store selection, and finds that spatial visibility and accessibility have different effects on user behaviour depending on the type and purpose of the activity. This paper reveals the influence of spatial and functional layout on user behaviour and puts forward the corresponding design strategy under the three-dimensional environment.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
