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RISS 인기검색어
- 검색키워드
- 저자 : Yifan Di (검색결과 2 건)
- 무료
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- 유료
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A new kind of rhodamine-based fluorescence turn-on probe for monitoring ATP in mitochondria
Liu, Yifan,Lee, Dayoung,Wu, Di,Swamy, K.M.K.,Yoon, Juyoung Elsevier 2018 Sensors and actuators. B Chemical Vol.265 No.-
<P><B>Abstract</B></P> <P>We have developed a new kind of colorimetric and fluorescence “turn-on” probe based on rhodamine derivatives for the detection of adenosine-5′-triphosphate (ATP) through hydrogen bond interactions. Upon the addition of 5 mM ATP, the probe 1 shows a 65-fold enhancement in fluorescence intensity and a color change from colorless to pink. The probe 2 also shows very obvious color and fluorescence change with the presence of ATP. The experimental results show that this kind of probe has high specificity towards ATP over other anions, metal ions, and other nucleoside polyphosphates, except ADP. The enhanced emission and naked eye changes are attributed to spirolactam ring-opening, which is pH independent (pH (4.0–7.4)). The more important finding from our results is that the electron withdrawing group in the chain decreases the binding ability to ATP. The live cell imaging experiments in Hela cells indicated that probe <B>2</B> has cell permeability, and mainly locates to mitochondria.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Three new rhodamine derivatives bearing thiourea group are synthesized and reported as chemosensors for ATP. </LI> <LI> Probe <B>1, 2</B> and <B>3</B> showed distinct colorimetric and fluorescence changes with ATP. </LI> <LI> Probe <B>2</B> was successfully applied to monitor ATP in mitochondria. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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Asynchronously Input-output Finite-time Control of Positive Impulsive Switched Systems
Leipo Liu,Hao Xing,Yifan Di,Zhumu Fu,Shuzhong Song 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.7
This paper considers asynchronously input-output finite-time control of positive impulsive switched systems(PISS). Firstly, the definition of input-output finite-time stability(IO-FTS) is introduced. By using the Lyapunov functional and average dwell time(ADT) approach, a state feedback controller is designed and new sufficient conditions are obtained to guarantee the corresponding closed-loop system is IO-FTS under asynchronous switching. Such conditions can be solved by linear programming. Finally, a practical example is provided to show the effectiveness of the proposed method.
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