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      • KCI등재

        백서에서 신경절단과 절치부 기능 상실에 따른 교근 및 악관절의 변화에 관한 연구

        양규호,김동민 大韓小兒齒科學會 1994 大韓小兒齒科學會誌 Vol.21 No.1

        This study was performed to evaluate, in growing rats, the changes of the masseter muscle and medibular joint to loss of incisal function and/or unilateral resection of the masseteric nerve. The animals were divided into two groups. The group I was received unilateral masseteric nerve resection only. The group II was received unilateral masseteric nerve resection and loss of incisal function with soft diet The results were as follows: 1. Denervated atrophy was identified in the first week after denervation. Nuclear migration into central portion of sarcoplasm, angulation of muscle fiber and ring fiber formation were also observed. The degree of denervation atrophy was more marked in group Ⅱ than in group Ⅰ. 2. The proportion muscle fiber types was variable, but type Ⅰ fiber was increased in group Ⅰ at SDH stain and group Ⅱ showed the largest proportion of type Ⅰ fiber at mtosin-ATPase stain. 3. The cross sectional area of masseter muscle after denervation was significantly reduced. The area of group Ⅰ was reduced in about 1/2 size than the control side, and group Ⅱ was reduced in about 1/3 size. 4. The cartilage capping of the surface of the mandibular condyle was composed of five layers at the first week after denervation. But the thickness of prechondroblastic layer was reduced in the second week after denervation in both groups, and the fourth week prechondroblastic and proliferative layer were reduced in group Ⅱ. The denervation of masseteric nerve altered the morphology of masseter, and active changes in muscle function influenced on temporomandibular jointmorphology. It suggested that continuous adjustment between the soft and hard tissue is preserved for balancing.

      • KCI등재

        데페록사민 전처치가 토끼 심근경색 크기의 감소에 미치는 효과

        양관모,오동렬,박승현,박규남,이원재,김형국,황두영,최승필,채장성 대한응급의학회 1998 대한응급의학회지 Vol.9 No.4

        Background: Reperfusion of ischemic myocardium has been postulated to result in a specific oxygen radical mediated tissue injury. Iron may liberate during ischemia and we hypothesized that administration of the iron chelator, deferoxamine during ischemia would result in improved recovery after postischemic reperfusion. Purpose: To test whether iron-catalyzed processes contribute to myocardial necrosis during ischemia and reperfusion, deferoxamine was administered to block iron catalyzed hydroxyl radical formation in rabbits. Methods: Eleven rabbits were divided into two groups : control group (n=5) and deferoxamine pretreatment group (n=6). The left circumflex coronay artery was ligated for 30 minutes and reperfused for 180 minutes. Area at risk (AR) was measured by non-stained area with methylene blue injection into left atrium after left circumflex coronary artery ligation. Infarct size was measured by weighing after triphenyltetrazolium chloride staining. Heart rate was measured using electrocardiographic recording and systemic blood pressure was monitored by pressure transducer connected to the catheter in the left ventricle. Results: 1. There was no significant difference of heart rate and blood pressure in deferoxamine pretreatment group compared with control group. 2. There was significant decrease of serum iron concentration after continuous infusion of deferoxamine compared with serum iron concentration before ligation of coronary artery(P<0.05). 3. There was no significant difference of area at risk between control and deferoxamine pretreatment group. 4. Area at necrosis to area at risk was significantly reduced in deferoxamine pretreatment group compared with control group(P<0.05). The results suggest that deferoxamine infusion prior to coronary artery occlusion has a significant benefit in reducing infarct size in this model.

      • KCI등재
      • KCI등재

        左則 上두骨 및 頰骨에 發生한 殲維性 骨異形成症의 治驗例

        梁棟奎,朴相俊,金秉民,金基元,金鍾烈 大韓顎顔面成形再建外科學會 1990 Maxillofacial Plastic Reconstructive Surgery Vol.12 No.3

        Fibrous dysplasia is an idiopathic skeletal disorder in which medullary bone is replaced and disturbed by poorly organized, structually unsound fibroosseous tissue, which may produce cortical expansion. When facial bones are involed, considerable esthetic deformity may result. The term monostotic fibrous dysplasia has been applied when one bone is involved : when more than one bone is affected, the term polyostotic used. The polyostotic form may be accomplished by pigmented skin lesion (Jaffe type), or by pigmented skin lesions with endocrine disturbance (Albright syndrome). No general agreement exists on the cause of fibrous dysplasia. A few authors have suggested that fibrous dysplasia arises as a resujlt of trauma. It occurs predominantly in infant, adolescent females and runs a variable clinical course. When several bones are involed, it tends to be unilateral. Involements of alveolar bone may produce displacement of teeth with malocclusion, or loss of teeth, or both. Radiographycally, ti shows an indistinctly delimited osteolytic defect with a bubble - like pattern, but without a sclerotic rim. The preferred treatment is almost always surgery. If the lesion is extensive, surgical intervention with use of recontouring procedures aimed at the correction of esthetic or funtional disturbances is preferred treatment. Now, we present a case of fibrous dysplasia on the left maxilla and the zygoma treated by bony contourign via hemicoronal flap and intraoral approach with good results.

      • 한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

        양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

        The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

      • KCI등재

        경부도상 피판을 이용한 구강내 결손부의 재건

        양동규,신상훈,서종천,이성근,김종렬 大韓顎顔面成形再建外科學會 1995 Maxillofacial Plastic Reconstructive Surgery Vol.17 No.3

        Various cutaneous as well as myocutaneous flaps have been designed for the reconstruction of tissue defects caused by the excision of oral cancer. Among these flaps, cervical island skin flap have been introduced by Farr et al and more have developed by Tashiro et al. This flap has many advantages. The flap minimizes donor size by use of cervical operation wound, flap size available is adequate for most oral defects and the procedure is relatively simple and time saving. However, this flap is not applicable in patients where there are large tissue defects and metastasis is suspected. We used this flap for it's rapid simple, and effective, primary closure of oral defects after cancer ablation and we have found this flap very useful for the reconstruction of relatively small oral defects.

      • SCOPUSKCI등재
      • 유두체-시상로의 신경종말에 관한 연구

        양남길,심동원,김종규,안의태 순천향대학교 1985 논문집 Vol.8 No.1

        This experiment was performed to define the ultrastructural character of axon terminal of mammillothalamic tract. The rats weighing 250∼300 gm were stereotaxically lesioned in the mammillary body. 2,7 and 14 days following the lesion, animals were sacrificed and perfused with 1% glutaraldehyde-1% paraformaldehyde solution(pH 7.2∼7.4), and anterior thalamic nuclei were punched out from the successfully lesioned brain. Tissue punchings were fixed in the same fixative as perfusion liquid overnight, immersed in the 2% osmic acid (pH 7.2∼7.4), dehydrated through alhcohol series, and embedded in the Araldite mixture. Degenerated axon terminals within the anterior thalamic nucleus following the mammillary lesion show two kinds of patterns, i,e., dark degeneration and lucent degeneration. Boutons of both types were asymmetrically synapsed with dendritic spine. Some boutons were synapsed directly with dendritic body, but from the correlative serial readings they showed the impression that they were originally synapsed with the spine. The result was contrasted with the former report that the synaptic type was defined as axo-dendritic one. The evidence suggests that axon-terminals of mammillothalamic tract make asymmetric axo-spinous synapses within anterior thalamic nucleus.

      • KCI등재

        OK-432(Picibanilⓡ)와 외과적 절제술을 이용한 선천성 림프관종의 치험례

        김일규,이성호,오성섭,최진호,오남식,김왕식,임영일,양동환 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.3

        Lymphangiomas are relatively rare benign tumors of the lymphatic system, characterized by congenital lymphatic malformation such as anastomosis or obstuction of the lymphatic channels. There are most frequently diagnosed in children younger than 3years. In contrast to that of the hemangioma, the sex distribution of the lymphangioma is nearly evenly divided. The head and neck lymphangioma represents about 70∼75% of all lymphangiomas, and they are difficult to manage. Spontaneous regression is rare, and rapid intermittent enlargement occurs secondary to infection or trauma. Enlargement may cause serious sequelae such as airway obstruction, feeding difficulties, and cosmetic problems. Treatments previously used for lymphangiomas include surgical excision and intralesional injection of sclerosants. Problems associated with surgical excision include the risk of cosmetically unacceptable scarring and the risk of damage to surrounding vital stricture and the high risk of incomplete excision. The sclerosants previously used have numerous other local and systemic side effects. This report describes a case that was successfully treated using OK-432 as a new sclerosant drug and secondary surgical excision for congential cavenous lymphangioma extensively enlarged to tongue, mouth floor and submandibular region.

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