A Comparative Study of Glottal Data from Normal Adults Using Two Laryngographs

Yang, Byung Gon,Wang, Soo Geun,Kwon, Soon Bok 한국음성과학회 2003 음성과학 Vol.10 No.1

A laryngograph was developed to meassssure the open and closed movements of vocal folds in our laboratory. This study attempted to evaluate its performance by comparing its glottal data with that of the orginal laryngograph. Ten normal Korean adults participated in the experiment. Each subject produced a sustained vowel /a/ for about five seconds. This study compared f0 values, contact quotients of the duration of closed vocal folds over one glottal pulse, and area quotients of the closed over open vocal folds derived from glottal waves using both the original and new laryngographs. Results showed that the mean and standard deviation of the two laryngographs were almost comparable with a correlation coefficient 0.662 but minor systematic shift below those fo the original laryngograph was observed. The absolute mean difference converged into 1㎐, which indicates a plssibility of adopting some threshold of rejecting inappropriate pitch values beyond a threshold value. The contact quotient of the normal subjects came out slightly over the 50% in a citation speech. Finally, the area quotient converged into 1. We will pursue further studies on the abnormal patients in the future.

An Acoustical Study on the Syllable Structures of Korean Numeric Sounds

Yang, Byung-Gon Korean Society of Speech Sciences 2007 음성과학 Vol.14 No.1

The purpose of this study was to examine the syllable structures of ten Korean numeric sounds produced by ten students. Each sound was normalized by its maximum intensity value and divided into onset, vowel, and coda sections after finding abrupt or visible changes in energy values or cumulative values of lower spectral energy at each pulse point using four Praat scripts. Then, segmental durations and cumulative intensity values of each syllable were obtained to find a statistical summary of the syllable structure. Intensity values at 100 proportional time points were also collected to compare the ten sounds. Results showed as follows: Firstly, there was not much deviation from the grand average duration and intensity for the majority of the sounds except the two diphthongal sounds on which their boundary points varied among the speakers. Secondly, the onset point for the CV or CVC category sounds and the boundary between the vowel and the nasal or lateral sound were easy to identify, which may be automatically traced later. Thirdly, there seems some tradeoff among the sections maintaining the same total duration per each syllable. Further studies on syllables with various onsets or codas would be desirable to make a general statement on the Korean syllable structure.

An Analysis of the English l Sound Produced by Korean Students

Yang, Byung-Gon Korean Society of Speech Sciences 2008 음성과학 Vol.15 No.1

The purpose of this study was to examine the English l sound in an English short story produced by 16 Korean students in order to determine various allophones of the sound using acoustic visual displays and perceptual judgments. The subjects read the story in a quiet office at normal speed. Each word included the lateral sound in onset or coda positions and before a vowel of the following word. Results showed as follows: Firstly, there was a durational difference between the two major groups. Also the majority of the subjects produced the clear l regardless of the contexts. Some students produced the sound as the Korean flap or the English glide [r]. A few missing cases were also seen. The dark l was mostly produced by the subjects of English majors in coda position with a few cases before a vowel in a phrase. Visual displays using the computer analysis were very helpful in distinguishing lateral variants but sometimes perceptual process would be necessary to judge them in fast and weak production of the target word. Further studies would be desirable to test the discrepancies between the acoustical and perceptual decisions.

An Acoustical Study of English Word Stress Produced by Americans and Koreans

Yang, Byung Gon 한국음성과학회 2002 음성과학 Vol.9 No.1

Acoustical correlates of stress can be classified asduration, intensity and fundamental frequency. This study examined the acoustical differences in the first two syllables of stressed english words produced by ten American and Korean speakers. The Korean subjects scored very high on the TOEFL. They read at a normal speed a fable from which theacoustical parameters of eight words were analyzed. In order to make the data comparison meaningful, each paramenter was collected at 100 dynamic time points proportional to the total duration of the two syllables. Then the ratio of the parameter sum of the firstrime to that of the second rime was calculated to determine the relative prominence of the syllables. Resultsshowed that the durations of the first two syllables were almost comparable between the Americans and Koreans. However, statistically significant differences showed up in the diphthong pronunciatious and in the words with the second syllable stressed. Also, remarkably high r-squared values were found between pairs of thethree acoustical parameters, which suggests that either one or a combination of two or more parameters mayaccount for the prominence of a syllable within a word.

Discrimination of Synthesized English Vowels by American and Korean Listeners

Yang, Byung-Gon Korean Society of Speech Sciences 2006 음성과학 Vol.13 No.1

This study explored the discrimination of synthesized English vowel pairs by twenty-seven American and Korean, male and female listeners. The average formant values of nine monophthongs produced by ten American English male speakers were employed to synthesize the vowels. Then, subjects were instructed explicitly to respond to AX discrimination tasks in which the standard vowel was followed by another one with the increment or decrement of the original formant values. The highest and lowest formant values of the same vowel quality were collected and compared to examine patterns of vowel discrimination. Results showed that the American and Korean groups discriminated the vowel pairs almost identically and their center formant frequency values of the high and low boundary fell almost exactly on those of the standards. In addition, the acceptable range of the same vowel quality was similar among the language and gender groups. The acceptable thresholds of each vowel formed oval to maintain perceptual contrast from adjacent vowels. The results suggested that nonnative speakers with high English proficiency could match native speakers' performance in discriminating vowel pairs with a shorter inter-stimulus interval. Pedagogical implications of those findings are discussed.

반폐쇄 순환여과식 넙치양식장의 수질제어에 관한 연구

양병수(Byung-Soo YANG),이헌모(Heon-Mo LEE),정병곤(Byung-Gon JEONG) 군산대학교 수산과학연구소 1994 군산대학교 수산과학연구소 연구논문집 Vol.2 No.-

넙치양식장의 수질관리 및 제어 방안을 검토하기 위하여 같은 조건에서 양식되고 있는 유수식 및 순환여과식 양식장을 선택하여 상호수질의 비교 평가를 행하였다. 두양식장 공히 COD, PO₄-P 및 SS의 최대농도느,ㄴ 급이와 동시에 나타났고 2시간 이내에 평상농도로 회복되어 일정한 농도로 거의 유지되었다. NH₄-N의 경우 유수식에는 금이후 시간 경과에 따라 농도차이가 별로 없으나 순환식의 경우는 금이후 2시간 이후에 다소 증가하는 경향을 보였다. NH₄-N을 제외한 COD, PO₄-P, SS 및 TIN의 농도는 순환여과식에서 다소 높은 경향을 보였다. 이는 처리 시스템내에 축적된 유기부유물이 무기화에 기인된 것을 평가되었으며, 이것이 질산화율을 떨어뜨리는 결과를 초래한 것으로 사려되었다. 유수식 및 순환여과식의 수질에 직접적인 영향을 주는 해수 교환율이 양식장마다 크게 다르게 나타나 이에 대한 최적화가 시급한 것으로 나타났다. A comparative evaluation of water quality in the existing semiclosed fish culture system was made to improve the system management. From the comparison of water quality quality between the flow-through mode and the recycle mode of the semiclosed system, the malfunctioning of the settling channel deteriorated water Quality and reduce the nitrification rate in the recycle mode. The peak concentrations of COD, PO₄-P and SS in the fish tanks appeared just after feeding, and then decreased to normal levels within two hours. However, the NH₄-N concentration increased slightly after two hours of feeding in the recycle mode. The water exchange rate was directly related to the water quality in the semiclosed fish culture system.

수소기질 결핍 환경하에서 수소분압이 슬러지 입상화에 미치는 영향

정병곤(Byung Gon Jeong),정형숙(Hyung Sook Chung),양병수(Byung Soo Yang) 大韓環境工學會 1996 대한환경공학회지 Vol.18 No.7

Two cases of actinic cheilitis treated with ingenol mebutate gel

( Byung Gon Choi ),( Min Seok Hur ),( Hye In Cheon ),( Song Hee Han ),( Hae Jeong Youn ),( Min Jung Kim ),( Nam Kyung Roh ),( Soo Young Kim ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Actinic cheilitis (AC) is considered as a precancerous disease that has potential to progress to invasive squamous cell carcinoma. Its treatment, therefore, should be radical, but the optimal therapy is not well established. Ingenol mebutate is a new topical drug extracted from plant Euphorbia peplus, which was approved by the US Food and Drug Administration for field therapy of actinic keratosis (AK) in 2012. Although it was approved for treatment of AK there are attempts of applying it on other lesions such as Bowen’s disease, squamous cell carcinoma and basal cell carcinoma. There is only one case report, however, of AC treatment with ingenol mebutate in Spain, and no report in Korean literature. We applied ingenol mebutate 0.015% gel to two 65-year-old patients (one is female and the other is male) diagnosed with AC by punch biopsy. We made a barrier surrounding the accurate lesion by antimicrobial ointment and conducted spot therapy for reducing local skin reaction (LSR) and drug inflow into intraoral cavity. Eight weeks after the treatment, the size of lesions was much decreased in both patients. The female patient showed almost complete clearance, and less than 50% of lesions remained of the male patient. Erosion, discharge and mild pain were accompanied as LSR, and resolved in 2 weeks. We report our experience and suggest that ingenol mebutate 0.015% gel could be an effective and safe treatment option for AC.

Characterization of a new ScbR-like γ-butyrolactone binding regulator (SlbR) in Streptomyces coelicolor

Yang, Yung-Hun,Song, Eunjung,Kim, Ji-Nu,Lee, Bo-Rahm,Kim, Eun-Jung,Park, Sung-Hee,Kim, Woo-Seong,Park, Hyung-Yeon,Jeon, Jong-Min,Rajesh, Thangamani,Kim, Yun-Gon,Kim, Byung-Gee Springer-Verlag 2012 Applied microbiology and biotechnology Vol.96 No.1

<P>gamma-Butyrolactones in Streptomyces are well recognized as bacterial hormones, and they affect secondary metabolism of Streptomyces. gamma-Butyrolactone receptors are considered important regulatory proteins, and various gamma-butyrolactone synthases and receptors have been reported in Streptomyces. Here, we characterized a new regulator, SCO0608, that interacted with SCB1 (gamma-butyrolactone of Streptomyces coelicolor) and bound to the scbR/A and adpA promoters. The SCO0608 protein sequences are not similar to those of any known gamma-butyrolactone binding proteins in Streptomyces such as ScbR from S. coelicolor or ArpA from Streptomyces griseus. Interestingly, SCO0608 functions as a repressor of antibiotic biosynthesis and spore formation in R5 complex media. We showed the existence of another type of gamma-butyrolactone receptor in Streptomyces, and this SCO0608 was named ScbR-like gamma-butyrolactone binding regulator (SlbR) in S. coelicolor.</P>

Effects of NASHA(non-animal stabilized hyaluronic acid) for facial skin rejuvenation: a randomized clinical trial, a split-face study

( Byung Gon Choi ),( Song Hee Han ),( Min Jung Kim ),( Hae Jeong Youn ),( Soo Young Kim ),( Nam Kyung Roh ),( Ho Jung Jung ),( Yu Ri Kim ),( Yang Won Lee ),( Yong Beom Choe ),( Kyu Joong Ahn ) 대한피부과학회 2015 대한피부과학회 학술발표대회집 Vol.67 No.2

Background: The mid-dermal injection of NASHA has been shown to be an effective method for skin rejuvenation. The previous manual technique made it difficult to precisely control the injection into themid-dermal layers and to achieve an even distribution of gel across the area. Objectives: This single-center, evaluator-blinded, prospective, split-face randomized clinical trial investigated the efficacy and safety of NASHA using a stamp-type electronic multi-needle injector, and analyzed the earlier skin physiological changes than previous trials.Methods: Twenty-five patients were recruited to this study. Each participant submitted to a single treatment with a NASHA injection to one side of the lower cheek. The skin hydration, melanin content, erythema, and elasticity of both cheeks were evaluated at each follow-up visit. Results: Stratum corneum hydration was significantlyimproved after NASHA injection. The corneometer readings for the treated side were significantly higher than for untreated side after the 2-, 4-, 8-, and 12-week treatment visits. Skin elasticity was also significantly improved during the course of the study. There is no significant effect on the melanin and erythema. Conclusion: NASHA treatment resulted in an improvement in the hydration and elasticity of the facial skin. The specialized stamp-type electronic multineedle injector enables the HA filler to rejuvenate the skin effectively and safely.