The Outcome of Fungal Pneumonia with Hematological Cancer

Eren Esma,Alp Emine,Cevahir Fatma,Tok Tuğba,Kılıç Ayşegül Ulu,Kaynar Leylagül,Yüksel Recep Civan 대한감염학회 2020 Infection and Chemotherapy Vol.52 No.4

Background: Fungal pneumonia is a common infectious complication of hematological cancer (HC) patients. In this retrospective study, the objective was set to identify the risk factors and outcome of fungal pneumonia in adult HC patients. Materials and Methods: This retrospective study was conducted with adult (>16 years) HC patients from January 2017 and December 2018. Results: During the study period, of 181 patients included 76 were diagnosed with fungal pneumonia. The most common HC was identified as acute myeloid leukaemia (40%). Of the participating patients, 52 (29%) were hematopoietic stem cell transplant (HSCT) recipients. The median age of patients with fungal pneumonia was significantly greater: 57 vs. 48 (odds ratio [OR]: 1.08) and they had longer hospitalization durations (OR: 1.14). Overall, 37 patients (20%) died, and 28-day mortality was significantly greater among patients with fungal pneumonia than without fungal pneumonia (33% vs. 11%). The most significant risk factors for mortality in fungal pneumonia were identified as need of intensive care unit (ICU) (OR: 191.2, P <0.001) and the need of vasopressor support (OR:81.6, P <0.012). ICU-mortality was (88%). Conclusion: Fungal pneumonia is a lethal complication in HC patients. Intensive care need is the most important predictive factor for mortality

Ginsenoside Re Protects Trimethyltin-Induced Neurotoxicity via Activation of IL-6-Mediated Phosphoinositol 3-Kinase/Akt Signaling in Mice

Tu, T. H.,Sharma, N.,Shin, E. J.,Tran, H. Q.,Lee, Y. J.,Jeong, J. H.,Jeong, J. H.,Nah, S. Y.,Tran, H. Y.,Byun, J. K. Springer Science + Business Media 2017 Neurochem Res Vol.42 No.11

Morphology and lightguide property investigation of a high quality DAST single crystal

Y.W.Chen-Yang,T.J.Sheu,S.S.Lin,Y.K.Tu 한국물리학회 2002 Current Applied Physics Vol.2 No.5

A high quality 40-dimethylamino-N-methyl-4-stilbazolium tosylate single crystal with dimension of 7. 7 . 1 m m3 was grown inthis study. The polarized optic microscopy photograph showed that the surface of this crystal was ordered and at. Three-dimensional luminance image analysis demonstrated that the intensity of a guided laser light passing through the single crystal alongits molecular structure alignment is stronger than that guided along a standard 8.5/125l m silica optic ber. The diameter of thel m, re-spectively. The FTIR spectrum implied that the single crystal is more suitable for use as a communication window than the dis-ordered polycrystalline samples. The result reveals that without further processing the single crystal can be used as a waveguide andis a promising candidate for electro-optic modulators and other active optical devices.. 2002 Elsevier Science B.V. All rights reserved.

Notch effect on creep damage for Hastelloy C276-BNi2 brazing joint

Luo, Y.,Jiang, W.,Zhang, W.,Zhang, Y.C.,Woo, W.,Tu, S.T. Scientific and Technical Press ; Elsevier Science 2015 Materials & Design Vol.84 No.-

The brazed structures have geometrical discontinuities like fillets working as notches. These notches have great effect on creep crack initiation and propagation. This paper studies the notch effect on creep damage for Hastelloy C276-BNi2 brazed joint, and the effects of notch type, notch radius and notch angle on creep damage have been investigated. The results show that the creep damage initiates in the filler metal. Different notch types bring different stress states, and generate different stress triaxialities and equivalent creep strains (CEEQs), leading to different creep damages. The maximum creep damage is generated in the notch tip for V-type notch, while the maximum creep damage is located at 0.4mm away from the notch tip for C-type notch. For U-type notch, the location of the maximum creep damage moves from the notch tip to the inside gradually as the notch radius increases. With the increase of notch radius and notch angle, the failure time of creep damage increases for U-type and V-type notches, while it decreases for C-type notch. The creep failure is prone to happen to V-type notch because it belongs to sharp notch.

SHAPE-SELECTIVE ISOPROPYLATION OF BIPHENYL OVER DEALUMINATED H-MORDENITES

Sugi, Y,Kim, J.H,Matsuzaki, T,Hanaoka, T,Kubota, Y,Tu, X,Matusmoto, M 전남대학교 촉매연구소 1993 촉매학술발표회 Vol.- No.10

Shape-selective alkylation using zeolitc is a useful way to introduce functional groups symmeetrically to aromatic hydrocarbons. One of important development on shape-selective catalysis achieved recently is the success in isopropylation of polynuclear aromatics, such as biphinyl and naphthalene over H-mordenite[1-5]. However, the mechanism of the catalysis related to solid acid sites and steric requirement in zeolite pores have not been fully understood. In this paper, we examine the isopropylation of biphenyland the ismerization of 4,4'-diisopropylbiphenyl over highly dealuminated H-mordenites, and discuss the mechanism of the catalysis.

Growth and residual stresses in the bonded compliant seal of planar solid oxide fuel cell: Thickness design of window frame

Jiang, W.,Zhang, Y.C.,Zhang, W.Y.,Luo, Y.,Woo, W.,Tu, S.T. Elsevier Ltd 2016 Materials & Design Vol.93 No.-

<P>Bonded compliant seal (BCS) is a new sealing method for planar solid oxide fuel cell. The BCS design uses a thin foil to bond the cell and window frame, which generates a multilayer structure. However, the high temperature bonding generates large residual stresses that greatly affect the fracture. This paper presents a numerical method and neutron diffraction measurement to study the residual stress, and effect of window frame thickness has been discussed. A grain boundary diffusion model incorporated with a power-law creep constitutive model is developed to calculate the growth stress in the oxide film. Then, the thermal elasto-plastic finite element method is applied to calculate the thermal stress. A neutron diffraction experiment is performed to measure the through thickness stresses. A good agreement is found between the calculation results and the neutron diffraction measurements. Compressive stress is generated in the oxide scale because of the substrate constraint. Furthermore, a competition exists between the generation of growth stress and the creep relaxation in the oxide layer. The residual stresses in the oxide layer decrease with the decrease in the substrate thickness. The thicknesses of the window frame and foil are designed to be 500 and 50 mu m, respectively. (C) 2015 Elsevier Ltd. All rights reserved.</P>

Genetic Diversity of 14 Indigenous Grey Goose Breeds in China Based on Microsatellite Markers

Tu, Yunjie,Chen, K.W.,Zhang, S.J.,Tang, Q.P.,Gao, Y.S.,Yang, N. Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.1

This experiment first cloned some microsatellite sequences for goose species by magnetic beads enriched method and studied the genetic structure research of 14 indigenous grey goose breeds using 19 developed and 12 searched microsatellite markers with middle polymorphism. According to the allele frequencies of 31 microsatellite sites, mean heterozygosity (H), polymorphism information content (PIC) and $D_A$ genetic distances were calculated for 31-microsatellite sites. The results showed that 25 of 31microsatellite sites were middle polymorphic, so the 25 microsatellite markers were effective markers for analysis of genetic relationship among goose breeds. The mean heterozygosity was between 0.4985 and 0.6916. The highest was in the Xupu (0.6916), and in the Yan was the lowest (0.4985) which was consistent with that of PIC. The phylogenetic tree was completed through analysis of UPGMA. Fencheng Grey, Shoutou, Yangjiang and Magang were grouped firstly, then Xongguo Grey, Wugang Tong, Changle and Youjiang were the second group; Gang, Yan Xupu and Yili were the third group; Yongkang Grey and Wuzeng were the fourth group. The results could provide basic molecular data for the research on the characteristics of local breeds in the eastern China, and a scientific basis for the conservation and utilization of those breeds.

Topic modeling and improvement of image representation for large-scale image retrieval

Tu, N.A.,Dinh, D.L.,Rasel, M.K.,Lee, Y.K. North-Holland [etc ; Elsevier Science Ltd 2016 Information sciences Vol.366 No.-

<P>In this paper, we present a new visual search system for finding similar images in a large database. However, there are a number of challenges regarding the robustness of the image representations and the efficiency of the retrieval framework. To tackle these challenges, we first propose an encoding technique based on soft-assignment of local features to convert an entire image into a single vector, which is a compact and discriminative representation. This encoded vector is suitable for most types of efficient indexing methods to produce an initial result. To compensate for the lack of incorporating geometric and object-related information during the encoding scheme, we then propose a probabilistic topic model to formalize the spatial structure among the local features. Moreover, the topic model allows us to effectively extract the object and background regions from the image. This is performed by a Markov Chain Monte Carlo algorithm for approximate inference. Finally, benefiting from the extracted objects in each image, we present a re-ranking scheme to automatically refine the initial search results. Our proposed retrieval framework has two major advantages: i) an aggregation strategy through soft-assignment improves the discriminative power of the representation, which has a determinative effect on the retrieval precision; and ii) the probabilistic latent topic model enables us to not only gain insight into the spatial structure of the image, but also handle a large variation in the object appearance. The experimental results from four benchmark datasets show that our approach provides competitive accuracy, and runs about ten times faster. Our studies also verify that proposed approach works effectively on large-scale databases of millions of images. (C) 2016 Elsevier Inc. All rights reserved.</P>

Levels of 4-1BB transcripts and soluble 4-1BB protein are elevated in the adipose tissue of human obese subjects and are associated with inflammatory and metabolic parameters

Tu, T H,Kim, C-S,Kang, J-H,Nam-Goong, I S,Nam, C W,Kim, E S,Kim, Y I,Choi, J I,Kawada, T,Goto, T,Park, T,Yoon Park, J H,Choi, M-S,Yu, R Macmillan Publishers Limited 2014 International journal of obesity Vol.38 No.8

Background:4-1BB, a member of the TNF receptor superfamily, has a role in various inflammatory pathologies through its interaction with 4-1BB ligand. We previously demonstrated that it participates in initiating and promoting obesity-induced adipose inflammation in a rodent model.Objective:In this study, we examined whether 4-1BB is related to obesity-induced adipose inflammation and metabolic parameters in humans.Methods:A total of 50 subjects, 25 obese (body mass index (BMI)⩾25 kg m<SUP>−2</SUP>) and 25 lean (BMI<23 kg m<SUP>−2</SUP>) participated in the study. The levels of 4-1BB transcripts and soluble 4-1BB protein (s4-1BB) in subcutaneous adipose tissue were measured by quantitative real-time PCR and enzyme-linked immunosorbent assay, respectively. Inflammatory and metabolic parameters were measured by enzymatic analysis and immunoassay.Results:Obese subjects had higher levels of both 4-1BB transcripts and s4-1BB protein in subcutaneous adipose tissue than lean controls, and the levels were correlated with BMI and the expression of inflammatory markers, as well as with serum metabolic parameters. Moreover, s4-1BB was released from human adipocytes, and elicited chemotactic responses from human monocytes/T cells as well as enhancing their inflammatory activity, indicating that it may promote human adipose inflammation.Discussion:Our data demonstrate that elevated levels of 4-1BB transcripts and s4-1BB in adipose tissue are closely associated with obesity-induced inflammation and metabolic dysregulation. They suggest that both 4-1BB transcripts and s4-1BB could serve as novel biomarkers and/or therapeutic targets for obesity-induced inflammation and metabolic syndrome in humans.

An Investigation of Mild Steel with Nitrogen-containing Inhibitor in Hydrochloric Acid

( Y. T. Horng ),( Yi Liang Tsai ),( Tu Ching Fang ),( Chien Ming Lee ),( F. I. Wei ),( H. C. Shih ) 한국부식방식학회 2003 Corrosion Science and Technology Vol.2 No.5