유동화 재순환 반응기에서 석유의 수소첨가 반응시 이탈된 온도제어

이창우,홍영호,함영민 한국산업안전학회 1998 한국안전학회지 Vol.13 No.2

This study was carried out to investigate the effect of on temperature control from actuating method, recycling ratio and the position (top, middle and bottom) of set and controlled temperature within the reactor in adiabatic ebullated recycling condition, when the disturbance was occured. Estimation of the solution were performed numerically using the finite difference method. It was assumed that the reaction is in constant with heat of reaction and the physical properties (density, heat capacity and viscosity, etc) of the reactants are same condition within the reactor.

A Model for Computer-Aided Process Planning System in Flexible Manufacturing Systems

Kang, Young-Sig,Hahm, Hyo-Joon,Rim, Suk-Chul,Kim, Seung-Baum The Korean Society for Quality Management 1994 품질경영학회지 Vol.22 No.1

Most of computer-aided process planning(CAPP) systems have been developed to automate the process planning function. In this paper, we describe an analytical model for a CAPP system in order to improve the performance of production system in flexible manufacturing systems(FMSs) for computer intergrated manufacturing(CIM) architecture. This paper proposes an optimal process planning that minimizes the load time by minimizing the cycle time and the number of workstations using Kang and Hahm's heuristic approach so as to improve the performance of production system under the batch production of discrete products. We also perform simulation using SIMAN language to campare the line utilization of each for various product types. The proposed algorithm can be implemented in existing FMSs for on-line control of product quantity using programmable logic controllers(PLC) and communication devices.

한국과 일본 대학생의 스포츠상황에 대한 도덕적 가치판단수준 비교

함정혜(Chung Hae Hahm) 한국여성체육학회 2013 한국여성체육학회지 Vol.27 No.1

The purpose of this study was to compare the differences of moral reasoning among general students, sports related majors students, and student athletes in Korea and Japan University. We collected total 612 out of 700 (315 from Korea, 297 from Japan) and 88 questionnaires were excluded questionnaire due to incompleteness and unreliable data. For this study, Hahm-Bellar Values Choice Inventory-16(HBVCI-16), which is a Moral Reasoning Questionnaire on Sports Activities, was used. The collected data was analyzed by t-test, one way ANOVA and two way ANOVA with using SPSS Var. 17.0 statistical package program and result were as follow. First, the Japan student`s overall score of moral reasoning were lower compare to Korean university students. Second, there were 1 % higher score of moral reasoning in woman against man and in younger subjects. Sports majored university students presented 1% higher score against other related students and higher grade students presented 5% higher score against lower grade students. Third, among student athletes of Korea and Japan, although there were no significant differences, it was 0.1% higher among those who engaged in individual sports and 5% higher score in those who have less sports career.

A Study of a Diet Improvement Method for Controlling High Sodium Intake Based on Protective Motivation Theory

Hahm, Tae-Shik,Choi, Sung-Hee,Lee, Tae-Yeon The Korean Society of Food Hygiene and Safety 2018 한국식품위생안전성학회지 Vol.33 No.2

고염식식습관은 다양한 질병을 일으키고 공중보건을 위협할 수 있다. 그 동안 고염식식습관을 통제하기 위한 다양한 시도가 이루어져 왔으나 건강커뮤니케이션을 통해 고염식식습관을 변화시킬 수 있는지에 대한 연구는 아직 이루어지지 못하였다. 본 연구는 고염식의위험성과 식습관의 통제가능성에 대한 인식이 고염식식습관을 얼마나 예측하는지를 검토함으로써 식습관 개선 교육을 위한 시사점을 찾고자 하였다. 이러한 연구목적을 달성하기 위해 보호동기 이론의 하위요인인심각성, 취약성, 효율성, 효능 및 행동 경향을 측정하기 위한 설문지를 개발하였으며 설문지를 충남소재 대학의 대학생들과 그들의 가족을 대상으로 배포하였다. 설문결과를 SPSS프로그램으로 분석한 결과를 보면 다음과 같다. 첫째, 청년층은 장년층보다 나트륨섭취가 더 많았다. 둘째, 상관관계분석에서 장년층은 고염식으로 인한 위험에 취약하다는 것을 알고 있지만 고염식을 억제할 수 있다고 확신할 때 까지는 식습관을 바꾸지 않는다. 셋째, 구조모델분석에 따르면 대처지각이 높을수록 고염식식습관의 경향성이 낮아지는 경향을 보인다. 이 결과는 고염식식습관을 줄이기 위해서는 실행 가능한 정보를 제공하고 저염식을 하였을 때 어떤 변화가 발생하는지를 인식 시킴으로써 대처지각을 높이는 방안이 더 효과적임을 시사한다. High sodium dietary habits may cause various diseases, thereby threatening the public health. Various efforts have been made to control high sodium use in diets, but few studies have been conducted on health communication efforts to modify such habits. This study looks for suggestions for diet improvement education by examining whether or not high sodium dietary habits can be predicted by a consumer's perception on the threat and controllability of high sodium diets. In this study, a questionnaire was developed to measure the severity, vulnerability, efficiency, efficacy, and behavioral tendencies of the consumer, which were subscales of the protective motivation theory. The questionnaire was given to university students and their families in Chungnam Province. The results of a statistical analysis were as follows: First, more young people preferred high-sodium diets than older people. Second, the correlation analysis showed that older people knew that they were vulnerable to the negative effects of high sodium diets, but they would not change their dietary habits until they were confident that they could control the high-sodium diet. Third, the structural model analysis showed that the higher the coping perception was, the lower was the tendency to consume a high-sodium diet. These results suggest that in the effort to reduce high-sodium diets, it is more effective to provide viable information and improve efficacy.

Secretory Expression of Human Growth Hormone in Saccharomyces cerevisiae Using Three Different Leader Sequences

Hahm, Moon-Sun,Chung, Bong-Hyun The Korean Society for Biotechnology and Bioengine 2001 Biotechnology and Bioprocess Engineering Vol.6 No.4

A recombinant human growth hormone(hGH) was expressed as a secretory product in the yeast Saccharomyuces cerevisiae. There different leader sequences derived from the mating fac-tor $\alpha$1(MF$\alpha$1) inulinase and invertase were used to direct the secretion of hGH into the extracel-lular medium. Among three leader sequences tested, the inulinase leader sequence was found to be the most efficient in the secretory expression of hGH. In contrast, no hGH was detected in the ex-tracellular medium with the invertase leader sequence. After 48 h shake-flask culture, the yields of hGH secreted into th emedium by the invertase. MF$\alpha$1 inulinase and invertase leader sequences were approximately 0, 0.3 and 0.9 mg/L, respectively. The secretion efficiencies were also found to be 0, 3.8 and 13% for the invertase , MG$\alpha$1 and inulinase leader sequences, respectively.

Chemoprevention of Helicobacter pylori-associated Gastric Carcinogenesis in a Mouse Model; Is It Possible?

Hahm, Ki-Baik,Song, Young-Joon,Oh, Tae-Young,Lee, Jeong-Sang,Surh, Young-Joon,Kim, Young-Bae,Yoo, Byung-Moo,Kim, Jin-Hong,Ha, Sang-Uk,Nahm, Ki-Taik,Kim, Myung-Wook,Kim, Dae-Yong,Cho, Sung-Won Korean Society for Biochemistry and Molecular Biol 2003 Journal of biochemistry and molecular biology Vol.36 No.1

Although debates still exist whether Helicobacter pylori infection is really class I carcinogen or not, H. pylori has been known to provoke precancerous lesions like gastric adenoma and chronic atrophic gastritis with intestinal metaplasia as well as gastric cancer. Chronic persistent, uncontrolled gastric inflammations are possible basis for ensuing gastric carcinogenesis and H. pylori infection increased COX-2 expressions, which might be the one of the mechanisms leading to gastric cancer. To know the implication of long-term treatment of antiinflammatory drugs, rebamipide or nimesulide, on H. pylori-associated gastric carcinogenesis, we infected C57BL/6 mice with H. pylori, especially after MNU administration to promote carcinogenesis and the effects of the long-term administration of rebamipide or nimesulide were evaluated. C57BL/6 mice were sacrificed 50 weeks after H. pylori infection. Colonization rates of H. pylori, degree of gastric inflammation and other pathological changes including atrophic gastritis and metaplasia, serum levels and mRNA transcripts of various mouse cytokines and chemokines, and NF-${\kappa}B$ binding activities, and finally the presence of gastric adenocarcinoma were compared between H. pylori infected group (HP), and H. pylori infected group administered with long-term rebamipide containing pellet diets (HPR) or nimesulide mixed pellets (HPN). Gastric mucosal expressions of ICAM-1, HCAM, MMP, and transcriptional regulations of NF-${\kappa}B$ binding were all significantly decreased in HPR group than in HP group. Multi-probe RNase protection assay showed the significantly decreased mRNA levels of apoptosis related genes and various cytokines genes like IFN-$\gamma$, RANTES, TNF-$\alpha$, TNFR p75, IL-$1{\beta}$ in HPR group. In the experiment designed to provoke gastric cancer through MNU treatment with H. pylori infection, the incidence of gastric carcinoma was not changed between HP and HPR group, but significantly decreased in HPN group, suggesting the chemoprevention of H. pylori-associated gastric carcinogenesis by COX-2 inhibition. Long-term administration of antiinflammatory drugs should be considered in the treatment of H. pylori since they showed the molecular and biologic advantages with possible chemopreventive effect against H. pylori-associated gastric carcinogenesis. If the final concrete proof showing the causal relationship between H. pylori infection and gastric carcinogenesis could be obtained, that will shed new light on chemoprevention of gastric cancer, that is, that gastric/cancer could be prevented through either the eradication of H. pylori or lessening the inflammation provoked by H. pylori infection in high risk group.

Endogenous cGMP regulates adult longevity via the insulin signaling pathway in <i>Caenorhabditis elegans</i>

Hahm, Jeong-Hoon,Kim, Sunhee,Paik, Young-Ki Blackwell Publishing Ltd 2009 AGING CELL Vol.8 No.4

<P>Summary</P><P>G-proteins, including GPA-3, play an important role in regulating physiological responses in <I>Caenorhabditis elegans</I>. When confronted with an environmental stimulus such as dauer pheromone, or poor nutrients, <I>C</I>. <I>elegans</I> receives and integrates external signals through its nervous system (i.e. amphid neurons), which interprets and translates them into biological action. Here it is shown that a suppressed neuronal cGMP level caused by GPA-3 activation leads to a significant increase (47.3%) in the mean lifespan of adult <I>C. elegans</I> through forkhead transcription factor family O (FOXO)-mediated signal. A reduced neuronal cGMP level was found to be caused by an increased cGMP-specific phosphodiesterase activity at the transcriptional level. Our results using <I>C. elegans</I> mutants with specific deficits in TGF-&bgr; and FOXO RNAi system suggest a mechanism in that cGMP, TGF-&bgr;, and FOXO signaling interact to differentially produce the insulin-like molecules, <I>ins-7</I> and <I>daf-28</I>, causing suppression of the insulin/IGF-1 pathway and promoting lifespan extension. Our findings provide not only a new mechanism of cGMP-mediated induction of longevity in adult <I>C. elegans</I> but also a possible therapeutic strategy for neuronal disease, which has been likened to brain diabetes.</P>

Occurrence of Bacterial Soft Rot of Lily Bulb Caused by Pectobacterium carotovorum subsp. carotovorum and Pseudomonas marginalis in Korea

Hahm, Soo-Sang,Han, Kwang-Seop,Shim, Myoung-Yong,Park, Jong-Jin,Kwon, Kyeong-Hak,Park, Jae-Eul The Korean Society of Plant Pathology 2003 Plant Pathology Journal Vol.19 No.1

Soft rot symptom was observed on lily bulb in the fields and at a low temperature storage house from 1999 to 2000 in Korea. The small dark-brown lesion appeared on the bulb, and enlarged and developed into the inner scales of the bulb. The bulb became water soaked and gave out unpleasant odor. Two different pathogenic bacteria were isolated from infected tissues. The causal bacteria were identified as Pectobacterium carotovorum subsp. carotovorum (Erwinia carotovora subsp. carotovora) and Pseudomonas marginalis based on bacteriological characteristics. Pathogenicity of the bacteria was proven by Koch's postulations. This is the first report of bacterial soft rot of lily bulb in Korea caused by the two bacteria.

Eclectic Global Marketing Strategy for the Multinational Companies(MNC) in the Hospitality Industry

Hahm Sung-Pil(함성필),Kim See-Hyung(김시형) 한국관광레저학회 2005 관광레저연구 Vol.17 No.1

Co-branding as an Alternative Franchising Strategy in the Restaurant Industry

Hahm Sung-Pil(함성필),Jun Jae-Kyun(전재균) 한국관광레저학회 2003 관광레저연구 Vol.14 No.3