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- 저자 : Xingping Zhang (검색결과 3 건)
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Xingping He,Dan Chen,Yan Guo,Xi Zhang,Yage Ma,Shenglan Zhao 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.6
Walnut kernel is a traditional Chinese herb recorded in the Chinese Pharmacopoeia with the efficacies of invigorating kidney, tonifying lung, and relaxing bowel. However, the potential mechanisms were unclear. This article aims to uncover the interdict mechanisms of walnut meal extracts (WMP) on high-fat diet (HFD) induced metabolic disorders in rats and reveal how the WMP benefits are associated with changes in the intestinal flora. Sprague-Dawley (SD) rats were fed a standard chow diet or an HFD for 18 weeks. After 6 weeks, the HFD rats were supplemented with 750 mg WMP/kg body weight or the vehicle for 12 weeks. The structure of gut microbiota was assessed by analyzing 16S rDNA sequences. WMP suppressed the weight gain and visceral obesity. WMP treatment also improved lipid profiles and increased antioxidative activities. WMP fully reversed hepatic steatosis with the upregulation of adipocytokines involved in lipid catabolism (e.g., adiponectin, PPAR-γ, visfatin, CEBPα) and the increased activities of lipoprotein lipase and hormone-sensitive lipase, which were associated with glucose tolerance improvement and insulin resistance (IR) mitigation. As revealed by 16S rDNA sequencing, WMP restored the diversity of intestinal flora reduced by HFD. WMP dramatically reduced the abundance of Gram-negative bacteria, especially Fusobacterium varium and Bacteroides vulgatus, and sharply increased the abundance of Lactobacillus animalis decreased by HFD. Our findings demonstrated that WMP suppressed the weight gain and adiposity in HFD-fed rats and fully reversed HFD induced IR and hepatic steatosis while dramatically reducing the abundance of Fusobacteriaceae and Enterobacteriaceae, underscoring the gut-liver axis as a primary target of walnut polyphenols.
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Jia Sun,Yimin Huang,Jun Han,Xingping Zhang 한국기상학회 2021 Asia-Pacific Journal of Atmospheric Sciences Vol.57 No.3
The Western Pacific Subtropical High (WPSH) is a principal component of the East Asian summer monsoon system. This study was to compare the relationship between theWPSH and summer precipitation in Dongting Lake basin (24°35′-30°27′N, 107°13′- 114°18′E) based on different datasets by employing the multivariate regression analysis. The observed precipitation data was from China Meteorological Data (CMD) sharing service system and the six gridded precipitation datasets were CFSR, ERA– Interim, CMAP, GPCP, CRU, and PREC/L, respectively. The WPSH exerted different influences on the precipitation of summer months. The indexes including westward extension ridge point index and northern boundary index in June, ridge line index and northern boundary index in July and August had important effect on the precipitation over Dongting Lake Basin. The gridded data could generally reproduce the relationship between the ridge line index and precipitation in July. The relationship between the northern boundary and the precipitation from gridded data was similar to that from observed data in June and July, while the relationship between the western extension ridge index and the precipitation in June could be reproduced by the gridded data except CFSR and ERA-Interim. Only in part area, the relationship between the intensity index and the CMD precipitation could be reproduced by gridded precipitation. The fitness of correlation in some area from the CMDcould be reproduced by the gridded data. General speaking, GPCP precipitation data was more applicable to the Dongting Lake Basin in studying on the relationship between the precipitation and a single index of WPSH.
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