페놀베타인 유도체합성(XI)

우성주,박예진,황순호,홍유화,김남재,김인종,김신규 慶熙大學校 1996 論文集 Vol.25 No.-

Tetrahydroberberine-13-one was treated with ethylchloroformate to give the C_8-N bond cleaved product 1. On the treatment with Lawesson's reagent (LAS), chloroketone 2 derived from the hydrolysis of 1 afforded the thioketone 3. On the other hand, spirotype-chloroketone 4 was transformed to diaziridine 8 by a reduction, chlorination and aziridine introduction. Also, spirotype-chlorothioketone 6 was obtained from chloroketone 4.

하악지시상분할절단술에서 자가수혈의 이용시 혈액학적변화에 관한 연구

김신헌,윤형기,박진혁,김우형,이희철,Park, Jin-Bae 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.4

Objective : s we has known risk of acquired immunodeficiency disease due to trans-fusion, we recognize the importance of autologous blood transfusion. Since 1990, the use of autologous blood transfusion was increased in Korea. The use of autologous blood transfusion in orthognathic surgery is common. The purpose of this research is to determine, in patients undergoing sagittal split ramus osteotomy, clinical predictive cri??eria for preoperative autologous blood donation and to propose guidelines to increase the efficiency of it. Methods and Material : This article reviewed one hundred two patient who had received bilateral sagittal split ramus osteotomy with autologous blood donation in oral and maxillofacial surgery, Paik hospital, Pusan, from January 1995 to December 1999. Hemoglobin & hematocrit change was evaluated pre- and postoperatively, and erythropoiesis, relationship between procedure time and blood loss was evaluated. Results : 1. Mean age of male patient was 23.1 years and that of female patient 22.5 years. Mean body weight was 73.7㎏ in male and 49.4㎏ in female. 2. Preoperative autologous blood donation unit was mean 1.9 unit(1unit=320㎖), and transfused unit was mean 1.3 unit. 3. Three of 102 patients had positive reaction for hapatitis B virus, but no complication were occurred. 4. The interval from initial donation of autologous blood to surgery was 19 days, and from last donation to surgery was 11 days. 5. Mean hemoglobin levels in predonation period were 15.1 g/㎗ in male and 12.7g/㎗ in female. Hemoglobin and hamatocrit levels decreased by 1.0g/㎗ and 3.2% in male and 1.1g/㎗ and 3.3% in female, respectively, after collection of 1 unit of autologous blood, and decreased by 1.8 g/㎗ and 6.4% in male and 1.9 g/㎗ and 6.9% in female after collection of 2 units. 6. Preoperative erythropoiesis from first donation to surgery showed no statistically significant difference between male and female patients. 7. Estimated blood volume(EBV) ranged from 4,100㎖ to 5,800㎖ in male and from 2,600㎖ to 3,600㎖ in female. Mean estimated blood loss(EBL) was 640㎖, and up to 32% of EBV. 8. All 25 patients with more than 20% loss of EBV were trnasfused intraoperatively, and 18 of 24 patient with 16-20% loss, 16 of 30 patient with l1~15% loss, 7 of 20 patient with less than 10% loss were transfused. Transfusion requirement was increased parallel to EBV. Conclusion : It seems that the proper unit of autologous blood donation is 1.3 unit, and autologous blood transfusion is a safe method in elective surgery that predicted large blood loss. In the future, if transfused blood was controlled based on hypotensive anesthesia, preoperative hemoglobin and hemotocrit level, the proper level of autologous blood transfusion will be accomplished.

80세 이상 노인 환자에서 시행한 슬관절 전치환술

김규현,고덕환,임신우,김동헌 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-

Purpose : The purpose of this study is whether total knee arthroplasty would be an effective procedure in the group over than eighty year-old patients. Materials and Methods : Between 1990 and 2001, 54 cases of the patients who are older than 80 year-old(group A) and 456 cases of the patients who are less than 80 year-old(group B) were treated by total knee arthroplasties and we evaluated the patients by Knee Score of American Knee Society and daily activity. Results : Pain was markedly improved in group A, and 30 of the patients(79%) participate the recreational activities, 32 patients(84%) could shop gloceries after surgery, and only 5 patients(13%) living in the house are neccessary for their family members. The mean knee score was 92 points and 91 points, pain score was 43 points in group A and 39 points in group B, and function score was 61 points in group A and 68 point in group B. Conclusion : Total knee arthroplasty still is a valuable procedure even for this elderly group, and most of these patients returned to a more functional lifestyle.

AUTO-ADPT 조타시스템에 있어서 적절한 조타모드의 선택에 관한 실선실험

신호식,김우숙 木浦海洋大學校 1998 論文集 Vol.6 No.2

PR-8000 autopilot system, in the training ship SAE YU DAL, provides two kinds of steering mode for the auto steering : these are the conventional PID steering mode and the adaptive steering mode(ADPT). Free combination of these two steering modes makes it possible to establish the stable control in all variation of weather at sea. ADPT steering mode has three selection modes, that is CONFINED(CONF.), ADJ. and OPEN mode. But there are not any correct data for field officers to use. Therefore in this experiment the writer analyzed the situations and suggested the proper way of steering mode selections with detected data through on-board experiment at sea.

당뇨병과 관련된 정신병리 : 정신증상, 특히 우울증상을 중심으로 Deal with Psychiatric Symptoms, Especially Depressive Symptoms

우이혁,최신영,김정기 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.3

This study was performed to find out psychopathological characteristics related with diabetes mellitus(DM) in comparison with known DM patients, newly diagnosed DM patients, normal subjects. These three groups were examined with Beck Depression Inventory(BDI) & Symptom Check List-90-Revision(SCL-90-R). The results were as follows : 1) Known DM patients showed significantly higher scores on BDI, and all subscales of SCL-90-R than normal subjects. 2) The BDI score of known DM patients was simillar with newly diagnosed DM patients while known DM patients showed significant differences in comparison with newly diagnosed DM patients on Depression and Obsession subscale in SCL-90-R. 3) The content of depressive symptoms of known DM patients was similar with that of newly diagnosed DM patients. 4) Newly diagnosed DM patients showed higher tendency on BDI score and Interpersonal sensitivity, Depression, Anxiety, Hostility, Phobic Anxiety subscale score of SCL-90-R than normal subjects. 5) There were no differences in BDI score and all of SCL-90-R subscale score according to prevalence of DM except somatization subscale. Our study suggests that depression may be predisposed to DM and the man who has high interpersonal sensitivity, anxiety, hostility, phobic anxiety is more susceptible to DM. Futhermore, DM makes worse preivious psychopathology probably. Therefore in the management of DM, it is important to treat them according to the aspects of depression and other psychopathological characteristics.

수종의 식물섬유의 급이가 고콜레스테롤 혈증 흰쥐의 지질 대사에 미치는 영향 : 1.간장의 지질성분 및 지방산 조성 Lipid Component and Fatty Acid Composition in liver

이호신,서인숙,김우준 麗水水産大學校 産業技術硏究所 1995 産業基術硏究所 論文集 Vol.4 No.-

This study was designed to observe the effects of feeding dietary fiber on the improvement of the lipids and the fatty acid metabolism in liver in dietary hypercholesterolemic rats. Experimental groups with 5% level of cellulose(A group as control group), chinese cabbage root(B group), tora stalk(C group) and sweet potato stalk(D group) were adminstered to the male rats of the Sprague-Dawley for 4 weeks. The results obtaind are as follows. Concentrations of total cholesterol, triglyceride and phospholipid in liver were significantly lower in the all experimental groups than in the control group, particularly, the lowest in the B group. Concentrations of free cholesterol and cholesteryl ester in liver were lower in the B group than in the other groups. In the fatty acid composition of total lipid, phospholipid, triglyceride and cholesteryl ester in liver, oleic acid in the MUFA was major fatty acid. From the above result, the feeding of chinese root was effective on the improvment of the lipid composition in liver.

하루 콩단백질 25g 섭취를 위한 메뉴작성 및 영양성분 분석

한재숙,김정애,서봉순,이연정,서향순,조연숙,한경필,이신정,오옥희,우경자,조은자,구성자,김수진,李承彦,南出隆久 동아시아식생활학회 2002 동아시아식생활학회지 Vol.12 No.2

The purpose of this study was to develop menus for daily intake of 25g soybean protein and to analyse nutrients of these foods. Analytical values were compared to the theoretical one using the food composition table and recommended dietary allowances for Koreans (7th revision). The results are as follows. 1. Soybean curd residue stew, Soybean curd, Kimchi saute, and hard boiled soybean and lotus root were selected for the menu for January, of which the content of soy bean protein(SBP) was 33.1g, soybean stew, soybean curd and soybean sprout saute, and Italian deep fried soybean curd were for February, of which the content of SBP was 35.0g. The content of SBP in soybean paste soup with soybean curd, fried soybean curd and fried soybean curd roll, the menu for March, was 24.9g. That of April were soybean curd gratin with soymilk, soybean curd and ham with garlic dressing and the content of SBP was 26.3g. That of May were soybean porridge, soybean flour cake with honey (Dasik), soybean sprout soup and the content of SBP was 26.7g. That of June were soymilk, pan-fried soybean curd, steamed soybean curd with chicken and the content of SBP was 28.4g. That of July were noodle with soymilk, mapatofu, soybean curd salad and the content of SBP was 24.7g. That of August were soybean sprout with mustard dressing, Tossed green pepper with raw soybean flour, Tofu and Kimchi stew, soybean curd steak and the content of SBP was 26.2g. That of September were Chinese cabbage soup with raw soybean flour, sweet and sour tofu and the content of SBP was 23.2g. That of Oct. were Fermented soybean stew, soybean pan cake and the content of SBP was 24.3g. That of November were not-pressed soybean curd casserole, pan-fried mashed soybean curd with egg, stir frying deep-fried soybean curd with vegetables and the content of SBP was 22.4g. That of December were soybean curd and mushroom casserole, fried soybean curd and vegetables, hard boiled soybean curd and the content of SBP was 28.9g. 2. The ratio of the analytical value over theoretical value (A/B%) of one serving in kcal, carbohydrate, protein, fat, ash and dietary fiber were 57.7~107.7%, 42.9~131.9%, 79.2~118.3%, 54.5~100%, 40.7~80.8% and 42.1~113.2%, respectively. 3. The ratio of A/B% of one serving in Ca, K, Na, P and Fe were 44.1~93.6%, 59.0~153.1%, 53.1~117.7% 64.6%~138.8 and 33.8~77.3%, respectively. That in Fe was the lowest among minerals. 4. The ratio of analytical value over Korean R.D.A(A/C%) in Ca was relatively higher (22.0~85.9%) than that in kcal(18~63%). 5. The ratio of A/C% in Fe was 25.1~64.3% and lower than that in Ca and protein in general.

光質이 채소作物의 種子發芽와 初期生育 및 除草劑의 活性에 미치는 效果

李政明,金侊來,權臣漢,曺哉銑,朴啓仁,全尙根,李承雨 경희대학교 부설 식량자원개발연구소 1987 硏究論文集 Vol.8 No.-

Studies were conducted to investigate the response of some horticultural plants to various light qualities provided by different kind of materials such as cellophane sheets, EVA, PVC(polyvinyl chloride,. and polyethylene (FE) films of different color. Major findings are summarized as follows. White fluorescence light and red light promoted seed germination of lettuce and inhibited that of radish seeds. Blue light inhibited the seed germination of both types of light-sensitive seeds. The light sensitivity varied considerably depending upon the kind of crops, cultivars, and the seed batches of the same cultivar. The blue light was equally or more strongly effective in inhibiting the seed germination as compared to the farred light. The growth of young seedlings developed from seeds was considerably promoted when grown under orange colored plastic film coverings The growth of larger seedlings was, however. not influenced by the color of plastic films Mulching pepper field with colored PVC film did not show further advantages over the commonly -used black PE film. Herbicidal activity of oxyfluorfen was very strong under natural light or red light conditions, and weak under blue or green light conditions The degree of oxyfluorfen-induced phytotoxicity varied considerably depending upon the light quality and the kind of vegetable crops.

光質이 채소作物의 種子發芽와 初期生育 및 除草劑의 活性에 미치는 效果

李政明,金侊來,權臣漢,曺哉銑,朴啓仁,金尙根,李承雨 慶熙大學校 1987 論文集 Vol.16 No.-

Studies were conducted to investigate the response of some horticultural plants to various light qualities provided by different kind of materials such as cellophane sheets, EVA, PVC(polyvinyl chloride, and polyethylene (PE) films of different color. Major findings are summarized as follows. White fluorescence light and red light promoted seed germination of lettuce and inhibited that of radish seeds. Blue light inhibited the seed germination of both types of light-sensitive seeds. The light sensitivity varied considerably depending upon the kind of crops, cultivars, and the seed batches of the same cultivar. The blue light was equally or more strongly effective in inhibiting the seed germination as compared to the farred light. The growth of young seedlings developed from seeds was considerably promoted when grown under orange colored plastic film coverings. The growth of larger seedlings was, however, not influenced by the color of plastic films. Mulching pepper field with colored PVC film did not show further advantages over the commonly-used black PE film. Herbicidal activity of oxyfluorfen was very strong under natural light or red light conditions' and weak under blue or green light conditions. The degree of oxyfluorfen-induced phytotoxicity varied considerably depending upon the light quality and the kind of vegetable crops.

고령의 불안정성 대퇴 전자간 골절시 대퇴거 대치형 주대를 이용한 양극성 고관절 반치환술

고덕환,김규현,신주용,임신우,김동현 대한골절학회 2003 대한골절학회지 Vol.16 No.1

목 적 : 고령의 대퇴골 전자간 불안정성 분쇄골절시 대퇴거 대치형 주대를 사용하여 인공관절 치환술을 시행한 후 수술 시간, 보행 시기, 및 그 기능적 결과와 합병증을 분석하고자 하였다. 대상 및 방법 : 1991년 8월부터 2001년 1월까지 본원에서 대퇴 전자간 불안정성 분쇄골절로 수술받은 75세 이상 환자중 대퇴거 대치형 주대를 이용한 양극성 고관절 반치환술을 시행받은 후 2년 이상 추시가 가능하였던 환자 20례를 대상으로 하였다. 결 과 : 수술 시간은 평균 45분이었고, 임상적 결과 분석에서 Harris Hip Score는 평균 84.7점이었다. 사각보행의 시기는 평균 8일이었으며, 전체중 부하는 평균 6.9주였다. 합병증으로 수술부위 감염 2례, 고도의 대퇴부 동통 1례 및 탈구 1례가 발생하였다. 결 론 : 고령의 환자에서 발생한 대퇴 전자간 불안정성 분쇄 골절의 치료에 있어서 대퇴거 대치형 주대를 이용한 양극성 고관절 반치환술은 비교적 조기 체중부하와 기능적 회복이 가능하고 낮은 합병증으로 좋은 치료법의 하나로 사료된다. Purpose : The purpose of this paper is to analyze the operating time, timing of ambulation, functional results and complications using the calcar replacement stem for the severely comminuted unstable intertrochanteric fractures in the eldertly patients. Materials and Methods : From August 1991 through January 2001, 20 elderly patients over the 75 year old patients had undergone bipolar hemiarthroplasty with calcar replacement stem for the treatment of unstable intertrichanteric fractures. Results : The mean operating time was 45 minutes and mean Harris Hip Score was 84.7. Ambulation with walker was started at post-operative 8 days and full weight bearing was 6.9 weeks, each. Complications were 2 cases of wound infection, 1 case of severe thigh pain and 1 case of dislocation. Conclusion : Early ambulation, functional restoration and decrease of the complications with bipolar hemiarthroplasty using calcar replacement stem for severely comminuted unstable intertrochanteric fractures in elderly patients, therefore this methods seems to be one of the effective treatments.