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        Comparative Effects and Safety of Full-Endoscopic Versus Microscopic Spinal Decompression for Lumbar Spinal Stenosis: A Meta-Analysis and Statistical Power Analysis of 6 Randomized Controlled Trials

        Zechuan Yang,Huan Wang,Wenkai Li,Weihua Hu 대한척추신경외과학회 2022 Neurospine Vol.19 No.4

        Objective: This meta-analysis with statistical power analysis aimed to evaluate the difference between full-endoscopic and microscopic spinal decompression in treating spinal stenosis. Methods: We searched PubMed, Embase, CENTRAL (Cochrane Central Register of Controlled Trials), and CNKI (China National Knowledge Infrastructure) for relevant randomized controlled trials (RCTs) regarding the comparison of full-endoscopic versus microscopic spinal decompression in treating lumbar spinal stenosis through February 28, 2022. Two independent investigators selected studies, extracted information, and appraised methodological quality. Meta-analysis was conducted using RevMan 5.4 and STATA 14.0, and statistical power analysis was performed using G*Power 3.1. Results: Six RCTs involving 646 patients met selection criteria. Meta-analysis suggested that, compared with microscopic decompression, full-endoscopic spinal decompression achieved more leg pain improvement (mean difference [MD], -0.20; 95% confidence interval [CI], -0.30 to -0.10; p = 0.001), shortened operative time (MD, -12.71; 95% CI, -18.27 to -7.15; p < 0.001), and decreased the incidence of complications (risk ratio, 0.43; 95% CI, 0.22–0.82; p = 0.01), which was supported by a statistical power of 98.57%, 99.97%, and 81.88%, respectively. Conclusion: Full-endoscopic spinal decompression is a better treatment for lumbar spinal stenosis, showing more effective leg pain improvement, shorter operative time, and fewer complications than microscopic decompression.

      • SERVICE TYPE AND CUSTOMER PRIVACY CONCERNS AFFECT ROBOT ADOPTION INTENTIONS

        Qi Yao,Chao Hu,Wenkai Zhou 글로벌지식마케팅경영학회 2023 Global Marketing Conference Vol.2023 No.07

        The proliferation of service robots has led to a growing concern about the impact of these technological advancements on privacy. Despite the development, quantitative research on the influence mechanism of privacy concerns on service robot adoption intentions is still limited. This research explores the influencing mechanism and boundary conditions of the interaction effect between customer privacy concerns and service type on customers’ service robot adoption intentions.

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        Efficiency of gerAa, tupA and ca transformation in Bacillus subtilis for self-healing of concrete cracks

        Hanxing He,Gefei Li,Jiantao Zhang,Jinlong Zhang,Mingyue Luo,Wenkai Hu,Yamin Lin,Ziyu Deng,Zhicheng Liu,Weizhao Chen,Xu Deng 한양대학교 세라믹연구소 2019 Journal of Ceramic Processing Research Vol.20 No.5

        A genetic approach was proposed to modify the characteristics of Bacillus subtilis strain WB800 (B. subtilis WB800) for selfhealing of concrete cracks. Three genes, namely gerAa which encodes germination receptors activated by L-alanine, tupA which is responsible for the synthesis of teichuronopeptide, and ca which encodes carbonic anhydrase (CA) catalyzing the synthesis of carbonate ion, were separately transformed into WB800. To protect bacterial cells from being squeezed, microspheres were produced with microcrystal cellulose (MCC) before the introduction of bacteria into the specimens. The results showed that the modified B. subtilis expressing GerA achieved 39.9% of germination ratio compared to 17% by the original host cells. With the transformation of tupA, the modified strain demonstrated higher resistance to alkaline environments, tolerating pH as high as 11, while the original strain only tolerated pH 9. The modified strain expressing CA induced more calcium carbonate than the original cells. Energy dispersive spectroscopy (EDS) identified the produced precipitate to be calcite (CaCO3). Moreover, a mathematical model was developed to optimize the influential factors of calcium precipitation process. Finally, based on the above results, an effective self-healing of concrete crack was achieved. This study may provide a promising strategy to improve the efficiency of bacterial self-healing of concrete cracks.

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