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- 저자 : Wen Shan YEW (검색결과 1 건)
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Repurposing Biology through Synthetic Enzymology
Wen Shan YEW 한국생물공학회 2021 한국생물공학회 학술대회 Vol.2021 No.4
Synthetic Enzymology has been increasingly used to engineer enzymes within biological systems for the repurposing of biology for purposeful function. On that note, the talk will touch on the Synthetic Cannabinoid Biology Programme (SCBP) that is part of the National Research Foundation’s (NRF) Synthetic Biology R&D Programme. The SCBP aims to discover new biosynthetic pathways that produce cannabinoid compounds in a sustainable manner. The SCBP does not study the psychoactive compounds of the cannabis plant, such as tetrahydrocannabinol (THC), which is illegal in Singapore. Instead, it identifies cannabinoid genes for the sustainable production of cannabinoids, such as cannabidiol (CBD). The SCBP does not use the cannabis plant as the aim is to produce non-psychoactive cannabinoids through synthetic biology, so that benefits of cannabinoid pharmaceuticals can be reaped without the use of the plant. In this talk, we will highlight some recent efforts in the sustainable production of cannabinoids using synthetic biology. In addition, the use of mechanistic and engineering principles in enzymology will also be highlighted to demonstrate the utility of synthetic enzymology in a range of applications from therapeutics to sustainable manufacturing to bioremediation.
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