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Sadiq Muhammad,Wen Fenghua,Dagestani Abd Alwahed 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.10
This study investigates the environmental footprint impacts of nuclear energy consumption in the presence of environmental technology and globalization of the ten largest ecological footprint countries from 1990 up to 2017. By considering a set of methods that can help solve the issue of cross-sectional dependence, we employ the Lagrange multiplier bootstrap cointegration method, Driscoll-Kraay standard errors for long-run estimation and feasible generalized least squares (FGLS) and panel-corrected standard errors (PCSE) for robustness. The finding revealed significant negative effects of nuclear energy consumption, environmental-related technology, population density and significant positive effects of globalization and economic growth on ecological footprint. These results are also robust by assessing the long-run impacts of predictors on carbon footprint and CO2 emissions as alternate ecological measures. These conclusions provide the profound significance of nuclear energy consumption for environmentally sustainable development in the top ten ecological footprint countries and serve as an important reference for ecological security for other countries globally.
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EMP3 Overexpression in Primary Breast Carcinomas is not Associated with Epigenetic Aberrations
Wei Zhou,Jinming Yu,Zheng Jiang,Xingang Li,Fenghua Xu,Yanbing Liu,Peie Wen,Li Kong,Ming Hou,Jinming Yu 대한의학회 2009 Journal of Korean medical science Vol.24 No.1
Epithelial membrane protein 3 (EMP3) is a trans-membrane signaling molecule with important roles in the regulation of apoptosis, differentiation and invasion of cancer cells, but the detailed is largely still unknown. We analyzed the mRNA levels and methylation statuses of EMP3 in 63 primary breast carcinomas and assessed their correlations with clinicopathologic variables. The expression of EMP3 mRNA in primary breast carcinomas was significantly higher than the expression of 20 normal breast tissues (p<10-7). EMP3 overexpression in breast carcinomas was significantly related to histological grade III (p=3.9×10-7), lymph node metastasis (p= 0.003), and strong Her-2 expression (p=3.3×10-6). Hypermethylation frequencies of EMP3 were detected in 36.5% of breast carcinomas by methylation-specific polymerase chain reaction. However, no significant correlations were found between methylation status of EMP3 and mRNA expression levels as well as other clinical parameters. In conclusion, EMP3 may be a novel marker of tumor aggressiveness. Overexpression of EMP3 in primary breast carcinoma is not associated with DNA methylation.
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