http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Richard Webb(Richard Webb ),Alison Early(Alison Early ),Bethan Scarlett(Bethan Scarlett ),Jack Andrew Clark(Jack Andrew Clark ),Jumo Doran(Jumo Doran ),Daniel Nash(Daniel Nash ),Michael G Hughes(Micha 사피엔시아 2021 Exercise Medicine Vol.5 No.-
Objectives: Genomic markers linked to exercise-associated health benefits and/or sporting performance are increasingly used to guide decision-making in healthcare and sport/exercise science. This project investigated whether the IL-6R SNP “rs2228145” might be provisionally designated a novel physical activity/exercise marker. rs2228145 results in an Aspartate358/Alanine358 change adjacent to the site where the IL-6R protein is cleaved into two fragments, resulting in ~two-fold increases in blood-borne levels of soluble IL-6R [‘sIL-6R’]. Methods: Cohorts of staff/students at Cardiff Metropolitan University donated/completed: [i] finger-prick capillary blood samples (subjected to ELISAs for sIL-6R, the associated signalling protein sgp130, and the IL-6/sIL-6R complex); [ii] cheek-swab samples containing buccal epithelial cell DNA (subjected to PCR-based IL-6R/rs2228145 genotyping assays); [iii] International Physical Activity Questionnaires (to estimate physical activity levels in the week preceding sample donation). Results: As expected, we observed significant genotype-dependent differences in blood-borne sIL-6R levels (CC (44.1±21.7ng/mL) vs. AC (28.6±7.3ng/mL) vs. AA (19.9±6.5ng/mL; P<0.05)); Importantly, AA homozygotes undertook significantly more physical activity than AC heterozygotes (6318±899 v. 3904±2280 MET-mins/week; P<0.01). Genotype was significantly associated with physical activity levels (P<0.05), and sIL-6R (P=0.197) and sgp130 (P=0.160) showed non-significant correlations with physical activity levels. Conclusions: These data suggest that IL-6R/rs2228145 genotype may influence participation in physical activity/exercise, perhaps by impacting on abilities to tolerate activity without experiencing adverse-effects. Although more research is required to confirm these preliminary findings, designation of IL-6R/rs2228145 as a novel marker, and determination of participants’ IL-6R/rs2228145 genotypes, may in future be useful tools to aid exercise-providers in designing personalised exercise programmes matched to clients/patients.
The impact of parametrized convection on cloud feedback
Webb, Mark J.,Lock, Adrian P.,Bretherton, Christopher S.,Bony, Sandrine,Cole, Jason N. S.,Idelkadi, Abderrahmane,Kang, Sarah M.,Koshiro, Tsuyoshi,Kawai, Hideaki,Ogura, Tomoo,Roehrig, Romain,Shin, Yech The Royal Society Publishing 2015 Philosophical transactions. Series A, Mathematical Vol.373 No.2054
<P>We investigate the sensitivity of cloud feedbacks to the use of convective parametrizations by repeating the CMIP5/CFMIP-2 AMIP/AMIP + 4K uniform sea surface temperature perturbation experiments with 10 climate models which have had their convective parametrizations turned off. Previous studies have suggested that differences between parametrized convection schemes are a leading source of inter-model spread in cloud feedbacks. We find however that ‘ConvOff’ models with convection switched off have a similar overall range of cloud feedbacks compared with the standard configurations. Furthermore, applying a simple bias correction method to allow for differences in present-day global cloud radiative effects substantially reduces the differences between the cloud feedbacks with and without parametrized convection in the individual models. We conclude that, while parametrized convection influences the strength of the cloud feedbacks substantially in some models, other processes must also contribute substantially to the overall inter-model spread. The positive shortwave cloud feedbacks seen in the models in subtropical regimes associated with shallow clouds are still present in the ConvOff experiments. Inter-model spread in shortwave cloud feedback increases slightly in regimes associated with trade cumulus in the ConvOff experiments but is quite similar in the most stable subtropical regimes associated with stratocumulus clouds. Inter-model spread in longwave cloud feedbacks in strongly precipitating regions of the tropics is substantially reduced in the ConvOff experiments however, indicating a considerable local contribution from differences in the details of convective parametrizations. In both standard and ConvOff experiments, models with less mid-level cloud and less moist static energy near the top of the boundary layer tend to have more positive tropical cloud feedbacks. The role of non-convective processes in contributing to inter-model spread in cloud feedback is discussed.</P>
Webb Keane 한국외국어대학교 HK 세미오시스 연구센터 2018 Signs and Society Vol.6 No.1
This article reviews the concept of semiotic ideology and its implications. Semiotic ideology refers to people’s underlying assumptions about what signs are, what functions signs serve, and what consequences they might produce. Those assumptions vary across social and historical contexts. But semiotic ideology as such is not a kind of false consciousness, nor is it something that some people have and others do not. Rather, semiotic ideology manifests the reflexivity that is inherent to the general human sign-using capacity. It ties general semiotic processes to specific judgments of ethical and political value: to take a sign a certain way is to take seriously the world it presupposes and, often, the life that that world recommends. Two examples show how attention to semiotic ideologies sheds light on the articulation of general semiotic processes with particular social, cultural, and political ones. The analysis of social class helps show some political implications of semiotic ideologies. Clashes over the status of religious signs reveal the ontological and ethical entailments of semiotic ideologies, in which the very existence of a sign’s object may be in dispute. Such ongoing semiotic processes help endow social existence with much of its constructive, uncertain, and conflictual character.
The Use of Enzymes to Diagnoses the Deficiency Copper in Plants
Webb, John 생화학분자생물학회 1988 BMB Reports Vol.15 No.4
Recently, much attentions have been paid on lipid peroxides in human body, mainly because of their involvement in pathogenesis of many degenerative diseases such as atherosclerosis and the aging. In the present lecture, a micro-method for the assay of serum lipid peroxide level, which was devised by the lecturer, will be introduced first. Then, the intervention of lipid peroxides in pathogenesis of some diseases will be mentioned. The relation to the vascular disorders will be described from both experimental and clinical observations. The role of lipid peroxides in provoking cataract will be proposed. It will be emphasized that the pathological increase of lipid peroxides in any tissue or organ results in their leakage to the blood serum, which in turn injures an intact tissue or organ.
LEARNING - BY - TRADING AND COMMERCIAL POLICY
WEBB, MICHAEL 한국국제경제학회 1993 International Economic Journal Vol.7 No.4
I first review the evidence that trade directly promotes technological progress, and of the roles of preparing-b-doing and adapting-by-doing. I use a simple model to show that when trade directly promotes progress, there may be a first-best argument for temporarily subsidizing trade. In analyze learning-by-trading in combination with preparing-by-doing or adapting-by-doing, plus the intersectoral spread of acquired technology. Two policy conflicts can occur that reverse policy prescriptions over time, calling for the sequential use of trade impediments and subsidies or production taxes and subsidies. [F13]
Anti-inflammatory Compounds from New Zealand Marine Organisms
Webb, Victoria L.,Pearce, A. Norrie,Maas, Elizabeth W. The Korean Society for Marine Biotechnology 2006 한국해양바이오학회지 Vol.1 No.3
The market for anti-inflammatory drugs is large and is expanding rapidly as populations age. Key to the development of new drugs are novel chemotypes. Marine organisms harbour a diverse range of unique compounds with applications in a multitude of disease indications. This review looks at anti-inflammatory compounds isolated from New Zealand marine organisms.
Advances In Air-Cooled Heat Exchanger Technology for Residential Air-Conditioning
Webb Ralph L.,Kim Nae-Hyun The Society of Air-Conditioning and Refrigerating 2005 International Journal of Air-Conditioning and Refr Vol.13 No.4
This paper describes the recent work on advanced technology concepts applied to air cooled heat exchangers for residential air-conditioning. The concepts include vortex generators for the air-side, micro-fin or flat tubes for the refrigerant-side. Advances in understanding of heat transfer mechanisms, predictive models are discussed.
Actantial Insights: Making Sense of Sport for Development Performance Account Management
Andrew Webb 글로벌지식마케팅경영학회 2022 Journal of Global Sport Management Vol.7 No.2
The purpose of this paper is to improve one proven method for understanding the management of performance accounts. This is important as there is currently a need for obtaining insights on how, what, and why performance accounts are used in both for profit and non-profit organisations in general, as well as in the more specific field of sport for development. To this end, I propose to add a second move to how previous management research operationalised Greimas and Courtés’ actantial model. A case study that ‘test-drives’ the two combined moves completes this study and raises important ethical questions regarding the translation of readers into actors through manipulation and sanctioning.