Research on the Digital Multimedia Technology and Urban Landscape Design based on Multimedia Art Perspective

Wang Aiqing,Wang Xitong,Hou Fengwu 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.10

21st century is the era of information technology, in this context, form and expression form of art also changed accordingly. The application of multimedia technology can enrich the morphological characteristics and color of different factors. In this paper, we research on the digital multimedia technology application in the urban landscape design, with the rapid development of computer technology, more technical conditions are provided for the multimedia interactive devices. In the design of urban landscape, the use of multimedia technology has also changed the past audio-visual experience, thus creating a novel landscape style. At the same time, we also analyze the computer assisted multimedia technology as CAD, 3D MAX and GIS, these soft wares can help the designer to complete the landscape design more effective, and under the condition of a virtual visualization .

Identification of Hub Genes in the Pathogenesis of Ischemic Stroke Based on Bioinformatics Analysis

Xitong Yang,Shanquan Yan,Pengyu Wang,Guangming Wang 대한신경외과학회 2022 Journal of Korean neurosurgical society Vol.65 No.5

Objective : The present study aimed to identify the function of ischemic stroke (IS) patients’ peripheral blood and its role in IS, explore the pathogenesis, and provide direction for clinical research progress by comprehensive bioinformatics analysis. Methods : Two datasets, including GSE58294 and GSE22255, were downloaded from Gene Expression Omnibus database. GEO2R was utilized to obtain differentially expressed genes (DEGs). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis of DEGs were performed using the database annotation, visualization and integrated discovery database. The protein-protein interaction (PPI) network of DEGs was constructed by search tool of searching interactive gene and visualized by Cytoscape software, and then the Hub gene was identified by degree analysis. The microRNA (miRNA) and miRNA target genes closely related to the onset of stroke were obtained through the miRNA gene regulatory network. Results : In total, 36 DEGs, containing 27 up-regulated and nine down-regulated DEGs, were identified. GO functional analysis showed that these DEGs were involved in regulation of apoptotic process, cytoplasm, protein binding and other biological processes. KEGG enrichment analysis showed that these DEGs mediated signaling pathways, including human T-cell lymphotropic virus (HTLV)-I infection and microRNAs in cancer. The results of PPI network and cytohubba showed that there was a relationship between DEGs, and five hub genes related to stroke were obtained : SOCS3, KRAS, PTGS2, EGR1, and DUSP1. Combined with the visualization of DEG-miRNAs, hsa-mir-16-5p, hsa-mir-181a-5p and hsa-mir-124-3p were predicted to be the key miRNAs in stroke, and three miRNAs were related to hub gene. Conclusion : Thirty-six DEGs, five Hub genes, and three miRNA were obtained from bioinformatics analysis of IS microarray data, which might provide potential targets for diagnosis and treatment of IS.

Model-free Controls of Manipulator Quadrotor UAV Under Grasping Operation and Environmental Disturbance

Xitong Guo,Xia Li,Shan Wang,Pingjuan Niu,Di Zhao,An Chang 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.11

Quadrotor unmanned aerial vehicle (UAV) is an ideal carrier for air transportation because of its simple structure and strong maneuverability that can complete vertical take-off and landing and hover operations. In recent years, the combination of quadrotor UAV and manipulator has attracted the most extensive attention. However, the quadrotor UAV will be significantly interfered with installing the manipulator, making control difficult. In this paper, a complete mathematical model of the manipulator quadrotor UAV is established. The model describes the interference of the manipulator and its operation to the quadrotor UAV. In order to suppress the interference caused by the manipulator, it is necessary to select the appropriate controller. Three model-free control algorithms are designed: proportional-integral-derivative (PID), sliding mode control based on RBF neural network (RBF-based SMC), and high order differential feedback controller (HODFC) and the derivation of RBF-based SMC and HODFC and the proof of closed-loop system are given. The PID controller has the worst anti-interference performance through the analysis of simulation experiments. On the other hand, RBF-based SMC has a time delay, HODFC has the strongest robustness to disturbance and excellent rapidity, which is an ideal method to control manipulator quadrotor UAV.

Association between Histone Deacetylase 9 Gene Polymorphism and Stroke in Chinese Han Population

Yang, Xitong,Xu, Hongyang,Liu, Dan,Ma, Rong,Zhang, Yuanyuan,Wang, Guangming The Korean Neurosurgical Society 2021 Journal of Korean neurosurgical society Vol.64 No.2

Objective : To explore the correlation between the polymorphism of histone deacetylase 9 gene (rs1060499865, rs723296, rs957960) and ischemic stroke (IS) in Chinese Han population in Dali region. Methods : This study included 155 IS patients and 128 healthy physical examinees. TaqMan-polymerase chain reaction technology and multivariate logistic regression were performed. Results : In the case group, there was no polymorphism of rs1060499865 observed in the two groups; whereas on the rs723296 locus the frequencies of C allele and TC genotype were significantly higher than that in the control group, alleles C and T were associated with a 2.158-fold increase in IS risk, and genotypes TC and TT were associated with a 2.269-fold increase in IS risk. The locus rs957960 exhibited no significant difference between the two groups. Conclusion : An association between rs723296 and the risk of IS was found in the Chinese Han population in Dali region. No significant association was found between rs1060499865, rs957960 and IS in the Chinese Han population in Dali region.

The Correlation between E-Selectin S128R Gene Polymorphism and Ischemic Stroke in Chinese Population : A Meta-Analysis

Yang, Xitong,Ma, Rong,Zhang, Yuanyuan,Wang, Guangming The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.5

To perform a systematic review of the data collected from case-control studies conducted earlier to investigate the correlation between E-selectin S128R polymorphism and ischemic stroke (IS) risk among the Chinese population. The PubMed, Web of Science, Chinese biomedical literature database (CBM), Chinese databases China National Knowledge Infrastructure (CNKI), WanfangData knowledge service platform (Wanfang Data), and information resource integration service platform (VIP) Databases were searched to retrieve case-control studies on the correlation between E-selectin gene S128R polymorphism and IS from the inception of the database till June 2019. The literature was screened, data were extracted, the risk of bias was reviewed, and the studies included were assessed independently by two reviewers. Stata ver. 12.0 software (Stata Corp LLC, College Station, TX, USA) was used to perform the meta-analysis. A total of 2907 cases from eight case-control studies involving 1478 IS patients and 1429 controls were included in this study. The R allele and RS genotype in E-selectin were found to be associated with the risk of IS as per the results of the meta-analysis (R vs. S : odds ratio [OR], 2.75; 95% confidence interval [CI], 2.15-3.51; p<0.00001; RS vs. SS : OR, 2.50; 95% CI, 1.95-3.19; p<0.00001; RR+RS vs. SS : OR, 2.85, 95% CI, 2.21-3.67; p<0.00001). The E-selectin gene S128R polymorphism is likely related to IS based on the results of a meta-analysis in the Chinese population, and the R allele and RS genotype of E-selectin may be IS risk factors.

Parallel Gene Loss and Acquisition Among Strains of Different Brucella Species and Biovars

Zhijun Zhong,Yufei Wang,Jie Xu,Yanfen Chen,Yuehua Ke,Xiaoyan Zhou,Xitong Yuan,Dongsheng Zhou,Yi Yang,Ruifu Yang,Guangneng Peng,Hai Jiang,Jing Yuan,Hongbin Song,Buyun Cui,Liuyu Huang,Zeliang Chen 한국미생물학회 2012 The journal of microbiology Vol.50 No.4

The genus Brucella is divided into six species; of these, B. melitensis and B. abortus are pathogenic to humans, and B. ovis and B. neotomae are nonpathogenic to humans. The definition of gene loss and acquisition is essential for understanding Brucella’s ecology, evolutionary history, and host relationships. A DNA microarray containing unique genes of B. melitensis Type strain 16MT and B. abortus 9-941 was constructed and used to determine the gene contents of the representative strains of Brucella. Phylogenetic relationships were inferred from sequences of housekeeping genes. Gene loss and acquisition of different Brucella species were inferred. A total of 214 genes were found to be differentially distributed,and 173 of them were clustered into 15 genomic islands (GIs). Evidence of horizontal gene transfer was observed for 10GIs. Phylogenetic analysis indicated that the 19 strains formed five clades, and some of the GIs had been lost or acquired independently among the different lineages. The derivation of Brucella lineages is concomitant with the parallel loss or acquisition of GIs, indicating a complex interaction between various Brucella species and hosts.