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RISS 인기검색어
- 검색키워드
- 저자 : Vira Kchorng (검색결과 2 건)
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Vira Kchorng,Md. Habibur Rahman,Johny Bajgai,Ailyn Fadriquela,Subham Sharma,Cheol-Su Kim,Kyu-Jae Lee 한국물학회 2021 한국물학회지 Vol.9 No.1
Vulvar area is susceptible to bacterial and fungal infection especially due to low pH environment. Thus, disruption of pH on skin (pH 5.5) and vagina (pH 3.5-4.5) can affect normal vaginal flora such as lactobasilli and lead to genitourinary infection by the growth of harmful bacteria. Currently the feminine cleanser is required to have further functions such as protection and improvement of a specific woman's diseases beside cleaning. The feminine cleanser (CellZyme Secret Therapy Plus, Pharmacal International Co. Ltd., Seoul, Korea) used in this study contains the functional substances such as human stem cell-conditioned media and various kinds of plants extract. we conducted this experiment to investigate the effects of the feminine cleanser on pathogenic bacteria and fungus. Three bacterial strains (Pseudomonas aeruginosa, Escherichia coli and Staphylococcus aureus), and one fungus (Candida albicans) were cultured in the blood agar, treated with a feminine cleanser, and incubated for 24 h at 37℃. Results demonstrated that a time-dependent treatment with a feminine cleanser markedly suppressed bacterial and fungal growth. In conclusion, the feminine cleanser containing stem cell-conditioned media and plants extract (CellZyme Secret Therapy Plus) showed anti-bacterial and anti-fungal effect, which is expected to help protection of genitourinay infection.
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Customer satisfaction of feminine cleanser containing human stem cell conditioned media
Vira Kchorng,Subham Sharma,Johny Bajgai,Ailyn Fadriquela,Md. Habibur Rahman,Cheol-Su Kim,Kyu-Jae Lee 한국물학회 2021 한국물학회지 Vol.9 No.1
Feminine cleanser is widely used for feminine hygiene because the vulva and vaginal surface are the most sensitive and fragile area. In particular, decreased estrogen level during menopause can cause genital symptoms (e.g., dryness, burning and irritation), sexual symptoms (e.g., lack of lubrication, pain, and impaired function) and urinary symptoms (e.g., urinary incontinence and urinary tract infection). Recently, commercial feminine cleanser shows the enhanced functions related with feminine health such as moisturizing, elasticity and anti-bacterial effect as well as cleaning. The aim of this study was to investigate the effect of the feminine cleanser (CellZyme Secret Therapy Plus, Pharmacal International Co. Ltd., Seoul, Korea) on various female-related symptoms in the women who have used this cleanser for over 1 month. The feminine cleanser used in this study was jelly-type formulation and it contains functional substances including human mesenchymal stem cell conditioned media (150,000ppm), peptides and various natural plant extract. The questionaire items were odor, leukorrhea, itching, dryness, vaginal contractile force, urinary incontinence and menstrual cramps. We divided into 5 grades according to the improvement degree of symptom: none (1), a little (2), moderate (3), good (4), and very good (5). Data was analyzed by using the IBM® SPSS® statistics tool. A total of 46 women responded on the survey, among them 28.26% was involved in the menopausal stage and 84% responded to be satisfied with the effect of the cleanser. According to the symptoms, respondents replied to have experienced positive effect (2 - 5 grades) as follows: foul smell 87%, leukorrhea 90%, and itching 96%, vaginal dryness 87%, vaginal contractile force 83%, urinary incontinence 61% and menstruation cramp (58%). In conclusion, the use of feminine cleanser is expected to useful for feminine hygiene and women's health through improvement of vulvar and vaginal environment such as pH and microflora.
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