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- 저자 : Uyan, Mikail (검색결과 2 건)
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Uyan, Mikail,Koca, Bulent,Yuruker, Savas,Ozen, Necati Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.3
Background: The aim of this study is to compare the numbers of axillary lymph nodes (ALN) taken out by dissection between patients with breast cancer operated on after having neoadjuvant chemotherapy (NAC) treatment and otherswithout having neoadjuvant chemotherapy, and to investigate factors affecting lymph node positivity. Materials and Methods: A total of 49 patients operated due to advanced breast cancer after neoadjuvant chemotherapy and 144 patients with a similar stage of the cancer having primary surgical treatment without chemotherapy at the general surgery clinic of Ondokuz Mayis University Medicine Faculty between the dates 01.01.2006 and 31.10.2012 were included in the study. The total number of lymph nodes taken out by axillary dissection (ALND) was categorized as the number of positive lymph nodes and divided into <10 and ${\geq}10$. The variables to be compared were analysed using the program SPSS 15.0 with P<0.05 accepted as significant. Results: Median number of dissected lymph nodes from the patient group having neoadjuvant chemotherapy was 16 (16-33) while it was 20 (5-55) without chemotherapy. The respective median numbers of positive lymph nodes were 5 (0-19) and 10 (0-51). In 8 out of 49 neoadjuvant chemotherapy patients (16.3%), the number of dissected lymph nodes was below 10, and it was below 10 in 17 out of 144 primary surgery patients. Differences in numbers of dissected total and positive lymph nodes between two groups were significant, but this was not the case for numbers of <10 lymph nodes. Conclusions: The number of dissected lymph nodes from the patients with breast cancer having neoadjuvant chemotherapy may be less than without chemotherapy. This may not always be attributed to an inadequate axillary dissection. More research to evaluate the numbers of positive lymph nodes are required in order to increase the reliability of staging in the patients with breast cancer undergoing neoadjuvant chemotherapy.
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Mechanical, Wear and Thermal Behaviors of Graphene Reinforced Titanium Composites
Mevlüt Gürbüz,Tuğba Mutuk,Pınar Uyan 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.4
In this study, the effects of graphene content (0.15, 0.30, 0.45 and 0.60 wt%) on the mechanical, tribological and thermalproperties of titanium matrix composites were investigated. The experimental results showed that the highest ultimatecompressive strength (845 MPa), tensile strength (613 MPa), lowest mass loss (0.6 mg for 10 N), and lowest wear rate(WR = 286 × 10−5 mm3/Nm for10 N) were obtained for Ti-0.15GNPs compared with pure titanium (652 MPa, 413 MPa,1 mg and 5 × 10−5 mm3/Nm, respectively). The wear rate of composites deteriorates with increasing applied load. Fromthe thermal analysis results, the best thermal conductivity (16 W/mK) and diffusivity (7.1 mm2/s) were performed for Ti-0.30GNPs composites at room temperature. The thermal behavior of the composites was decreased with increasing graphenecontent and temperature. It concluded that graphene is an effective reinforcement to develop the mechanical, wear and thermalbehavior of titanium matrix composites.
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