교잡종 찰옥수수에 대한 연구 : Ⅱ. 새로 육성된 찰옥수수 교잡종 "대덕찰"에 대한 농업적 특성 Ⅱ. Agronomic Characteristics of the New Waxy Hybrids "Daedukchals"

이희봉,김효기,김동욱,김준표,정재영,최현구,강윤규 충남대학교 농업과학연구소 2002 농업과학연구 Vol.29 No.2

1. 새로 육성된 4개의 대덕찰 찰옥수수 교잡종에 대한 간장은 대조구인 찰옥 1호보다 큰 반면에 개화기는 약 4∼7일 늦었으며, 모든 공시 교잡종의 주당 분얼수는 한 개이하의 무효분얼로 나타났다. 2. 새로 육성된 대덕찰옥수수의 이삭길이와 직경은 대조구인 찰옥 1호보다 크게 나타났으며, 특히 대덕찰옥수수 1호와 2호의 과피두께는 대구조보다 얇았고, 당도 역시 높게 나타나 우수 교잡종으로 평가되었다. Stem height of the new developed "Daedekchals" waxy hybrids were higher than check hybrid. Chalok #1, while days to tasseling were delayed about four to seven days. Number of tillers per plant of the these new hybrids including check were appeared to be one less as non-effective tiller. Ear length and diameter of the new waxy hybrids were longer and thicker than check, respectively. In addition pericarp thickness of the Daedekchal #1 and #2 among new developed waxy hybrids were thinner and sugar content were higher than check.

40세 이하 관상동맥 질환자에서 장기적 임상 관찰

이승욱,정명호,박종철,박형욱,조상희,김원,김계훈,이상현,강경태,조장현,김남호,김건형,안영근,조정관,박종춘,강정채 全南大醫大 2001 전남의대학술지 Vol.37 No.2

Clozapine 투여후 설사와 혈소판 감소증이 나타난 환자 1례

김진희,이창욱,김정진,김우선,백인호 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.3

The clozapine has been used to the treatment of schizophrenic patients unresponsive to conventional antipsychotics, but to administration of clozapine has been restricted because of its propensity to cause agranuloytosis. So side effects associated with the administration of clozapine have probably not been fully elucidated. The authors describe a case of a male schizophrenic who developed prefuse diarrhea, spiking fever and thrombocytopenia associated with the administration of clozapine. Discontinuance of clozapine therapy resulted in improvement of diarrhea and fever followed by normalization of the platelet count. Previous reports of adverse hematologic side effects and gastroenteric reaction induced by clozapine administration are also discussed. We suggest that the physician must keep in mind these side effects and administer clozapine cautiously.

유색미에 관한 연구 : Ⅰ. 감마선 처리에 의해 유래된 Dohoku 유색미 돌연변이체의 주요 특성 Ⅰ. Characteristics of Dohoku color rice mutants derived by Gamma-ray Mutagenesis

이희봉,최현구,김동욱,김준표,정재영,정종태 충남대학교 농업과학연구소 2002 농업과학연구 Vol.29 No.2

1. 돌연변이체 DM-1과 DM-2의 간장은 양친인 Dohoku나 대구조인 흑진주벼보다 짧은 반면에 출수기는 7일내지 20일가량 늦어졌다. 2. 이들 DM-1과 DM-2의 수장은 대조구와 비슷하였으나 주당 이삭수는 대조구와 같이 DM-2에서 매우 많았다. 3. 선발된 계통들에 대한 주당 영화수는 대조구보다 적었으나 영색은 갈색내지 짙은 자주색으로 다양한 변이를 보였고 까락길이 역시 변이가 컸다. 4. 안토치안 색소에 대한 공시계통간 차이를 optical density(OD_(530))값으로 나타낸 결과 DM-2 변이계통에서 2.23, DM-3 변이계통에서 2.26으로 나타나 대조구인 흑진주벼의 2.59보다 크게 낮았다. Culm length of Dohoku mutant 1(DM 1) and mutant 2(DM 2) were shorter than Dohuko parent and Heukjinjubyo check, while days to heading were delayed seven to 20 days Panicle length of these were similar to check and number of panicle per plant of DM 2 was highly appeared than check. Spikelets per plant of the selected lines were lower than check, and glume color of these were varied from brown to dark purple and awn length was also varied according to line used. Anthocyanin content of each mutant line as measured by 530㎚ were lower than that of check in that OD 2.23 and OD 2.26 for DM 1 and DM 2, respectively, and 2.59 for check.

예술전공(무용, 음악, 미술) 대학생과 비예술전공 대학생의 성격 특성에 관한 연구

이종희,안정욱 경희대학교 체육과학연구소 2000 體育學論文集 Vol.28 No.-

This thesis is purposed to find what influences the art exercise on the principle of the personality shoping guidance. This processes in this way to research how the arts form an individual personality through investigating a differentia of the personality shaping in the female arts majors(dance, music, art) from one in the female general majors as a comparative group. The result of this research by using questionnaire for the female arts majors with over 5 years experience and the female general majors in a senior college located in Seoul follows The arts majors make no sensible differences between themselves on the point of the personality shaping factors (leadership, stability, brightness, adaptability, correspondency, sociality Ⅰ, sociality Ⅱ).

단감의 이용성 증대를 위한 protopectinase처리 가공기술 개발

하정욱,이대희,김기운,황용일 慶南大學校 附設 基礎科學硏究所 2002 硏究論文集 Vol.16 No.-

가공식품의 개발에 있어서 식품의 맛과 더불어 저장성, 열 안정성 및 색조유지는 소비자의 기호도에 중요한 영향을 미친다. B. subtilis EK11 유래의 protopectinase(PPase)는 식물조직 중엽부의 주성분인 불용성 protopectin을 분해하여 단세포화하는 효소이다. PPase를 단감에 작용시켜 단감 고유의 세포 속에 함유되어 있는 세포내 성분들의 파손 없이 단세포를 유리하였다. PPase처리된 단감 단세포화물의 착즙 후 회수율과 잔사율은 각각 95%와 5%로서, 기계적 마쇄물에서의 85%와 15%에 비하여 높은 회수율과 낮은 잔사율을 나타내었다. 총당, 환원당, 자당, 조단백질, 조지방 및 조섬유의 함량변화는 큰 차이가 없었으며, 이는 단세포 처리에 의하여 이들 성분이 안정하게 유지됨을 알 수 있었다. 식품중 열 또는 빛에 가장 불안정한 비타민 C의 경우 단감 단세포화물은 1일 경과 후에도 50% 이상이 보존되는 것으로 보아 단세포에 의한 일반적인 구성성분이 안정하게 유지 보호됨을 알 수 있다. PPase로 처리된 단감 단세포화물을 4℃에서 9일간 저장하며 색조를 관찰한 결과, 단세포화물에서는 뚜렷한 색조의 차이가 없었고 기계적 마쇄물에서는 변색이 일어났다. 또한 단감 단세포화물을 100℃에서 60분간 열처리한 후 관찰한 결과, 기계적 마쇄물의 경우 짧은 처리에도 변화를 보였으나 단세포화물에서는 그다지 큰 변화가 없었으며 이는 효소적 단세포화물의 높은 열 안정성을 의미한다. PPase를 이용한 단감의 단세포화는 음료제조 및 원료보존에 유용하게 응용가능하며, 나아가 단감 단세포화물의 폭넓은 식품소재화 가능성과 고부가가치 기능성 식품제조에 이용될 수 있음을 의미한다. In development of the processed food, it is important not only to make the food delicious but to enhance its storage span and thermal stability without change of the food quality in color, which greatly affects the tastes of customers. Protopectinase (PPase) from Bacillus subtilis EK11 hydrolyses or dissolves protopectin in the middle lamella of plant tissues with the resultant separation of plant cells from each other, called enzymatic maceration. With the PPase, persimmon was enzymatically macerated to separate cells to primary cell wall without damage. Yields of persimmon treated with PPase and mechanical maceration were 95% and 85%, respectively. Total and reducing sugars, crude protein and fat in the enzymatic maceration were well preserved as in the mechanical maceration. Importantly, over 50% of vitamin C, which is the most unstable component in application of the mechanical maceration, remained with intact form for one day after the enzymatic treatment. When the suspensions of persimmon macerated with both treatments had been stored at 4℃ for 9 days, the suspension of mechanically macerated persimmon was decolorized. Whereas decolorization was not found in the enzymatically macerated persimmon. Moreover, the mechanically macerated persimmon was greatly deteriorated after heat treatment at 100℃ for 60 min; the cell suspension of the enzymatically separated persimmon appeared to be stable, indicating the thermal stability. Thus, the PPase treatment of persimmon could be a better choice for preparation of the highly valuable and functional processed food as well as for prolonging the preservation period.

금속가공유 사용 근로자에서 발생한 과민성폐장염 1예

이선웅,고동희,진구원,박동욱,이정탁,송윤희,이상윤 大韓産業醫學會 2008 대한직업환경의학회지 Vol.20 No.1

서론: 과민성폐장염의 원인물질로 금속가공유는 외국의 경우 작업장의 집단발병 사례들을 중심으로 많은 보고가 되어 왔으나 우리나라에서는 아직 보고되지 않았으며,저 자들은 금속가공유에 1년간 노출된 근로자에서 발생한 과민성폐장염 1예를 발견하였기에 작업환경측정을 시행한 후 작업관련성을 평가하여 보고하는 바이다. 증례: 64세 남자 환자가 1년간 강관을 절단하는 작업을 한 후 호흡곤란을 주소로 내원하였다 노출력,임상적 소견 및 방사선학적 소견을 토대로 과민성폐장염으로 진단되었다. 작업환경 측정결과 공기 중 금속가공유,엔도 톡신,총 세균 및 곰팡이는 각각 0.531 mg/m³, 6.33 EU/m³ 100 CFU/m³ 및 75 CFU/m³이었고,금속가 공유 내 엔도톡신,총세균 및 곰팡이는 각각 1.5x10⁴EU/mL,4.6x10^(5) CFU/mL 및 1.8×10^(5) CFU/mL이었다. 고찰: 금속가공유 내의 원인항원에 대한 침강항체를 검사하지 못했으나,작업환경 측정결과 금속가공유가 일반적인 허용가능 수준 이상으로 오염되었으며,기존의 과민성폐장염 발생 사례들과 비슷한 수준 또는 그 이상으로 오염되어 있었다. 공기 중 금속가공유 농도 역사 NIOSH의 REL과 ACGIH의 NIC를 초과하고,기존의 사례들에 비해서도 대체적으로 높은 수준 이었다. 금속가공유 이외의 다른 원인에 대한 감별과 기존의 발생사례들과의 노출수준 비교를 통하여,저자들은 환자가 금속가공유에 의한 미생물 항원에 노출되어 과민성폐장염이 발생한 것으로 판단하였다. Introduction: There have been no reports of hypersensitivity pneumonitis caused by metal working fluids in Korea, despite their existence in other countries. Here, we report the first such case, along with an assessment of work-relatedness through exposure assessment. Case report: A 64-year old male patient visited the hospital with dyspnea after metal pipe cutting for about a year. He was diagnosed with hypersensitivity pneumonitis from the evidence of specific exposure history, clinical symptoms, and radiologic findings. The air exposure levels of the oil mist, endotoxin, total bacteria and fungus in the work environment was TWA(8-hr) 0.531 mg/m³, 6.33 EU/m³, 100 CFU/m₃ and 75 CFU/m³, respectively. The concentrations of the endotoxin, total bacteria and fungus within the metal working fluid was 1.5 X 10⁴EU/mL, 4.6 X 10^(5) CFU/mL and 1.8 X 10^(5) CFU/mL, respectively. Discussion: Although the patient did not receive a specific precipitating antibody test, the microbial concentration within the metal working fluid was higher than normal and similar to previous case reports, The oil mist level in the air exceeded the NIOSH REL and ACGIH NIC, and were similar or higher than previous cases. By excluding other causes of hypersensitivity pneumonitis, we concluded that the disease developed from exposure to microbial antigens in the metal working fluid.

보건관리 대행사업 평가도구의 타당성, 신뢰도 및 인과관계 검증에 관한 연구

박정일,조병희,구정완,김광종,김현욱,원종욱,이명숙,정문희 가톨릭대학교 산업의학센터 2001 韓國의 産業醫學 Vol.40 No.1

In order to verify the validity, reliability and relativeness of preliminary evaluation tool for the group occupational health services(GOHS), a questionnaire survey for doctors, nurses and hygienists of 18 GOSH institutions, and employers, health managers and employees of 340 enterprises was conducted. A factor analysis and correlation test for the statistical validity of the variables in the evaluation tool, a Chronbach's Alpha value for the reliability in the evaluation indices and a regression analysis for the relations of the evaluation model were performed. The results were as follows: 1.In factor analysis, thirty-three variables among 43 variables were selected as significant variables, ie 9 out of 11 for input index, 11 out of 14 for throughout index and 13 out of 18 for out put index. 2.Three evaluation(outcome) scales(evaluation by employer, health manager and employee) which composed of 16 identical items were used. 3.The Chronbach's Alpha values of input, throughout, out put and outcome indices were 0.5221, 0.5473, 0.7122 and 0.8546 respectively. 4.Regression equations of independent variables on the evaluation scales of employer, health manager and employee were all statistically significant.

EM알고리즘에 의한 다변량 혼합정규분포하의 분류방법

황강진,박정욱,유희경 三陟大學校 2000 論文集 Vol.33 No.1

Cluster analysis is a technique for unsuoervised classification which the group information is not available. General cluster analysis uses euclidean distance as a measure of group similarity. However, it might cause some problem such as ignoring the pattern of the groups which is characterized by the relationships between variables. Hence general clustering method can lead to misclassification problem. It is worth considering mixture distributions for the classification. That is each cluster or group has its own distribution and they are mixed together. The main purpose here is to find which group has the maximum probability for each observation to be classified. EM algorithm is a useful technique to find the maximum likelifood estimator from incomplete data. In this paper, we assume that each group follows multivariate normal distribution and consider that the given data are incomplete because there is not the group information. We introduce new variable which indicates the group information. Then the augmented data becomes complete data. EM algorithm is used to estimated conditional expection for group information variable from the complete likelifood function. The effect of EM algorithm is compared to k-means clustering by misclassification probability.

Antimicrobial Effects of Flavone Analogues and Their Structure-Activity Relationships

( Jung Mo Young ),( Young Hee Park ),( Yong Uk Lee ),( Ho Jung Kim ),( Yhong Hee Shim ),( Joong Hoon Ahn ),( Yoong Ho Lim ) 한국미생물생명공학회 2007 Journal of microbiology and biotechnology Vol.17 No.3